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Journal Abstract Search

386 related items for PubMed ID: 28033363

  • 1. Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype.
    Gabriel D, Gordon LB, Djabali K.
    PLoS One; 2016; 11(12):e0168988. PubMed ID: 28033363
    [Abstract] [Full Text] [Related]

  • 2. Sulforaphane enhances progerin clearance in Hutchinson-Gilford progeria fibroblasts.
    Gabriel D, Roedl D, Gordon LB, Djabali K.
    Aging Cell; 2015 Feb; 14(1):78-91. PubMed ID: 25510262
    [Abstract] [Full Text] [Related]

  • 3. Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture.
    Rivera-Torres J, Acín-Perez R, Cabezas-Sánchez P, Osorio FG, Gonzalez-Gómez C, Megias D, Cámara C, López-Otín C, Enríquez JA, Luque-García JL, Andrés V.
    J Proteomics; 2013 Oct 08; 91():466-77. PubMed ID: 23969228
    [Abstract] [Full Text] [Related]

  • 4. All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype.
    Pellegrini C, Columbaro M, Capanni C, D'Apice MR, Cavallo C, Murdocca M, Lattanzi G, Squarzoni S.
    Oncotarget; 2015 Oct 06; 6(30):29914-28. PubMed ID: 26359359
    [Abstract] [Full Text] [Related]

  • 5. Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts.
    Eisch V, Lu X, Gabriel D, Djabali K.
    Oncotarget; 2016 Apr 26; 7(17):24700-18. PubMed ID: 27015553
    [Abstract] [Full Text] [Related]

  • 6. Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells.
    Aveleira CA, Ferreira-Marques M, Cortes L, Valero J, Pereira D, Pereira de Almeida L, Cavadas C.
    J Gerontol A Biol Sci Med Sci; 2020 May 22; 75(6):1073-1078. PubMed ID: 32012215
    [Abstract] [Full Text] [Related]

  • 7. Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome.
    Finley J.
    Med Hypotheses; 2018 Sep 22; 118():151-162. PubMed ID: 30037605
    [Abstract] [Full Text] [Related]

  • 8. Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells.
    Cao K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, Collins FS.
    Sci Transl Med; 2011 Jun 29; 3(89):89ra58. PubMed ID: 21715679
    [Abstract] [Full Text] [Related]

  • 9. Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways.
    Clements CS, Bikkul MU, Ofosu W, Eskiw C, Tree D, Makarov E, Kill IR, Bridger JM.
    Biogerontology; 2019 Jun 29; 20(3):337-358. PubMed ID: 31041622
    [Abstract] [Full Text] [Related]

  • 10. Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition.
    Glynn MW, Glover TW.
    Hum Mol Genet; 2005 Oct 15; 14(20):2959-69. PubMed ID: 16126733
    [Abstract] [Full Text] [Related]

  • 11. Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome.
    Capell BC, Erdos MR, Madigan JP, Fiordalisi JJ, Varga R, Conneely KN, Gordon LB, Der CJ, Cox AD, Collins FS.
    Proc Natl Acad Sci U S A; 2005 Sep 06; 102(36):12879-84. PubMed ID: 16129833
    [Abstract] [Full Text] [Related]

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  • 13. Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decrease DNA damage respectively, in Hutchinson-Gilford progeria syndrome fibroblasts.
    Bikkul MU, Clements CS, Godwin LS, Goldberg MW, Kill IR, Bridger JM.
    Biogerontology; 2018 Dec 06; 19(6):579-602. PubMed ID: 29907918
    [Abstract] [Full Text] [Related]

  • 14. Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation.
    Yang SH, Bergo MO, Toth JI, Qiao X, Hu Y, Sandoval S, Meta M, Bendale P, Gelb MH, Young SG, Fong LG.
    Proc Natl Acad Sci U S A; 2005 Jul 19; 102(29):10291-6. PubMed ID: 16014412
    [Abstract] [Full Text] [Related]

  • 15. Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.
    McClintock D, Gordon LB, Djabali K.
    Proc Natl Acad Sci U S A; 2006 Feb 14; 103(7):2154-9. PubMed ID: 16461887
    [Abstract] [Full Text] [Related]

  • 16. Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment.
    Columbaro M, Capanni C, Mattioli E, Novelli G, Parnaik VK, Squarzoni S, Maraldi NM, Lattanzi G.
    Cell Mol Life Sci; 2005 Nov 14; 62(22):2669-78. PubMed ID: 16261260
    [Abstract] [Full Text] [Related]

  • 17. Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes.
    Kreienkamp R, Croke M, Neumann MA, Bedia-Diaz G, Graziano S, Dusso A, Dorsett D, Carlberg C, Gonzalo S.
    Oncotarget; 2016 May 24; 7(21):30018-31. PubMed ID: 27145372
    [Abstract] [Full Text] [Related]

  • 18. Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson-Gilford Progeria Syndrome.
    Wheaton K, Campuzano D, Ma W, Sheinis M, Ho B, Brown GW, Benchimol S.
    Mol Cell Biol; 2017 Jul 15; 37(14):. PubMed ID: 28483909
    [Abstract] [Full Text] [Related]

  • 19. Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.
    Chojnowski A, Ong PF, Wong ES, Lim JS, Mutalif RA, Navasankari R, Dutta B, Yang H, Liow YY, Sze SK, Boudier T, Wright GD, Colman A, Burke B, Stewart CL, Dreesen O.
    Elife; 2015 Aug 27; 4():. PubMed ID: 26312502
    [Abstract] [Full Text] [Related]

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