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354 related items for PubMed ID: 28038482

  • 1. Microsomal Metabolism of Prochiral Polychlorinated Biphenyls Results in the Enantioselective Formation of Chiral Metabolites.
    Uwimana E, Maiers A, Li X, Lehmler HJ.
    Environ Sci Technol; 2017 Feb 07; 51(3):1820-1829. PubMed ID: 28038482
    [Abstract] [Full Text] [Related]

  • 2. 2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) is enantioselectively oxidized to hydroxylated metabolites by rat liver microsomes.
    Wu X, Pramanik A, Duffel MW, Hrycay EG, Bandiera SM, Lehmler HJ, Kania-Korwel I.
    Chem Res Toxicol; 2011 Dec 19; 24(12):2249-57. PubMed ID: 22026639
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  • 3. Microsomal oxidation of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) results in species-dependent chiral signatures of the hydroxylated metabolites.
    Wu X, Kammerer A, Lehmler HJ.
    Environ Sci Technol; 2014 Feb 18; 48(4):2436-44. PubMed ID: 24467194
    [Abstract] [Full Text] [Related]

  • 4. Gas chromatographic analysis with chiral cyclodextrin phases reveals the enantioselective formation of hydroxylated polychlorinated biphenyls by rat liver microsomes.
    Kania-Korwel I, Duffel MW, Lehmler HJ.
    Environ Sci Technol; 2011 Nov 15; 45(22):9590-6. PubMed ID: 21966948
    [Abstract] [Full Text] [Related]

  • 5. Oxidation of polychlorinated biphenyls by liver tissue slices from phenobarbital-pretreated mice is congener-specific and atropselective.
    Wu X, Duffel M, Lehmler HJ.
    Chem Res Toxicol; 2013 Nov 18; 26(11):1642-51. PubMed ID: 24107130
    [Abstract] [Full Text] [Related]

  • 6. Human Liver Microsomes Atropselectively Metabolize 2,2',3,4',6-Pentachlorobiphenyl (PCB 91) to a 1,2-Shift Product as the Major Metabolite.
    Uwimana E, Li X, Lehmler HJ.
    Environ Sci Technol; 2018 May 15; 52(10):6000-6008. PubMed ID: 29659268
    [Abstract] [Full Text] [Related]

  • 7. 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) Is Atropselectively Metabolized to para-Hydroxylated Metabolites by Human Liver Microsomes.
    Uwimana E, Li X, Lehmler HJ.
    Chem Res Toxicol; 2016 Dec 19; 29(12):2108-2110. PubMed ID: 27989147
    [Abstract] [Full Text] [Related]

  • 8. Chiral polychlorinated biphenyls are biotransformed enantioselectively by mammalian cytochrome P-450 isozymes to form hydroxylated metabolites.
    Warner NA, Martin JW, Wong CS.
    Environ Sci Technol; 2009 Jan 01; 43(1):114-21. PubMed ID: 19209593
    [Abstract] [Full Text] [Related]

  • 9. Stereoselective formation of mono- and dihydroxylated polychlorinated biphenyls by rat cytochrome P450 2B1.
    Lu Z, Kania-Korwel I, Lehmler HJ, Wong CS.
    Environ Sci Technol; 2013 Jan 01; 47(21):12184-92. PubMed ID: 24060104
    [Abstract] [Full Text] [Related]

  • 10. Effects of thiol antioxidants on the atropselective oxidation of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) by rat liver microsomes.
    Wu X, Lehmler HJ.
    Environ Sci Pollut Res Int; 2016 Feb 01; 23(3):2081-8. PubMed ID: 26155892
    [Abstract] [Full Text] [Related]

  • 11. Identification of a novel hydroxylated metabolite of 2,2',3,5',6-pentachlorobiphenyl formed in whole poplar plants.
    Ma C, Zhai G, Wu H, Kania-Korwel I, Lehmler HJ, Schnoor JL.
    Environ Sci Pollut Res Int; 2016 Feb 01; 23(3):2089-98. PubMed ID: 26676542
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  • 15. Metabolism of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) atropisomers in tissue slices from phenobarbital or dexamethasone-induced rats is sex-dependent.
    Wu X, Kania-Korwel I, Chen H, Stamou M, Dammanahalli KJ, Duffel M, Lein PJ, Lehmler HJ.
    Xenobiotica; 2013 Nov 01; 43(11):933-47. PubMed ID: 23581876
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  • 16. In vitro hepatic metabolism of polychlorinated biphenyls with different chlorine-substituted structures in rats and humans: Kinetics, metabolism, and potential nuclear receptor affinities.
    Chenchen H, Keqi H, Yanhong Z, Yiye J, Yankuan T, Xiaojun L, Bixian M.
    Sci Total Environ; 2023 Mar 15; 864():161043. PubMed ID: 36549545
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  • 18. 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) and its hydroxylated metabolites are enantiomerically enriched in female mice.
    Kania-Korwel I, Barnhart CD, Stamou M, Truong KM, El-Komy MH, Lein PJ, Veng-Pedersen P, Lehmler HJ.
    Environ Sci Technol; 2012 Oct 16; 46(20):11393-401. PubMed ID: 22974126
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  • 19. Human hepatic microsomal sulfatase catalyzes the hydrolysis of polychlorinated biphenyl sulfates: A potential mechanism for retention of hydroxylated PCBs.
    Duffel MW, Tuttle K, Lehmler HJ, Robertson LW.
    Environ Toxicol Pharmacol; 2021 Nov 16; 88():103757. PubMed ID: 34688910
    [Abstract] [Full Text] [Related]

  • 20. Comparative metabolism of polychlorinated biphenyls and tissue distribution of persistent metabolites in rats, hamsters, and Guinea pigs.
    Haraguchi K, Koga N, Kato Y.
    Drug Metab Dispos; 2005 Mar 16; 33(3):373-80. PubMed ID: 15608140
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