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Journal Abstract Search

571 related items for PubMed ID: 28055960

  • 1. Genetic disruption of the pHi-regulating proteins Na+/H+ exchanger 1 (SLC9A1) and carbonic anhydrase 9 severely reduces growth of colon cancer cells.
    Parks SK, Cormerais Y, Durivault J, Pouyssegur J.
    Oncotarget; 2017 Feb 07; 8(6):10225-10237. PubMed ID: 28055960
    [Abstract] [Full Text] [Related]

  • 2. Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia.
    McDonald PC, Chafe SC, Brown WS, Saberi S, Swayampakula M, Venkateswaran G, Nemirovsky O, Gillespie JA, Karasinska JM, Kalloger SE, Supuran CT, Schaeffer DF, Bashashati A, Shah SP, Topham JT, Yapp DT, Li J, Renouf DJ, Stanger BZ, Dedhar S.
    Gastroenterology; 2019 Sep 07; 157(3):823-837. PubMed ID: 31078621
    [Abstract] [Full Text] [Related]

  • 3. Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.
    Chiche J, Ilc K, Laferrière J, Trottier E, Dayan F, Mazure NM, Brahimi-Horn MC, Pouysségur J.
    Cancer Res; 2009 Jan 01; 69(1):358-68. PubMed ID: 19118021
    [Abstract] [Full Text] [Related]

  • 4. ZEB1 transcriptionally regulated carbonic anhydrase 9 mediates the chemoresistance of tongue cancer via maintaining intracellular pH.
    Zheng G, Peng C, Jia X, Gu Y, Zhang Z, Deng Y, Wang C, Li N, Yin J, Liu X, Lu M, Tang H, He Z.
    Mol Cancer; 2015 Apr 15; 14():84. PubMed ID: 25890268
    [Abstract] [Full Text] [Related]

  • 5. The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths.
    Swietach P, Patiar S, Supuran CT, Harris AL, Vaughan-Jones RD.
    J Biol Chem; 2009 Jul 24; 284(30):20299-310. PubMed ID: 19458084
    [Abstract] [Full Text] [Related]

  • 6. Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma.
    Said HM, Hagemann C, Carta F, Katzer A, Polat B, Staab A, Scozzafava A, Anacker J, Vince GH, Flentje M, Supuran CT.
    Bioorg Med Chem; 2013 Jul 01; 21(13):3949-57. PubMed ID: 23706268
    [Abstract] [Full Text] [Related]

  • 7. Role of the HBx oncoprotein in carbonic anhydrase 9 induction.
    Holotnakova T, Tylkova L, Takacova M, Kopacek J, Petrik J, Pastorekova S, Pastorek J.
    J Med Virol; 2010 Jan 01; 82(1):32-40. PubMed ID: 19950233
    [Abstract] [Full Text] [Related]

  • 8. CREB is a key negative regulator of carbonic anhydrase IX (CA9) in gastric cancer.
    Wang G, Cheng Z, Liu F, Zhang H, Li J, Li F.
    Cell Signal; 2015 Jul 01; 27(7):1369-79. PubMed ID: 25843777
    [Abstract] [Full Text] [Related]

  • 9. Elevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomas.
    Guan X, Luo L, Begum G, Kohanbash G, Song Q, Rao A, Amankulor N, Sun B, Sun D, Jia W.
    J Exp Clin Cancer Res; 2018 Oct 17; 37(1):255. PubMed ID: 30333031
    [Abstract] [Full Text] [Related]

  • 10. Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion.
    Robertson N, Potter C, Harris AL.
    Cancer Res; 2004 Sep 01; 64(17):6160-5. PubMed ID: 15342400
    [Abstract] [Full Text] [Related]

  • 11. Extracellular acidosis elevates carbonic anhydrase IX in human glioblastoma cells via transcriptional modulation that does not depend on hypoxia.
    Ihnatko R, Kubes M, Takacova M, Sedlakova O, Sedlak J, Pastorek J, Kopacek J, Pastorekova S.
    Int J Oncol; 2006 Oct 01; 29(4):1025-33. PubMed ID: 16964400
    [Abstract] [Full Text] [Related]

  • 12. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer.
    Giatromanolaki A, Koukourakis MI, Sivridis E, Pastorek J, Wykoff CC, Gatter KC, Harris AL.
    Cancer Res; 2001 Nov 01; 61(21):7992-8. PubMed ID: 11691824
    [Abstract] [Full Text] [Related]

  • 13. Tumor microenvironment conditions alter Akt and Na+/H+ exchanger NHE1 expression in endothelial cells more than hypoxia alone: implications for endothelial cell function in cancer.
    Pedersen AK, Mendes Lopes de Melo J, Mørup N, Tritsaris K, Pedersen SF.
    BMC Cancer; 2017 Aug 14; 17(1):542. PubMed ID: 28806945
    [Abstract] [Full Text] [Related]

  • 14. Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival.
    Logsdon DP, Shah F, Carta F, Supuran CT, Kamocka M, Jacobsen MH, Sandusky GE, Kelley MR, Fishel ML.
    Sci Rep; 2018 Sep 13; 8(1):13759. PubMed ID: 30214007
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells.
    Meehan J, Ward C, Turnbull A, Bukowski-Wills J, Finch AJ, Jarman EJ, Xintaropoulou C, Martinez-Perez C, Gray M, Pearson M, Mullen P, Supuran CT, Carta F, Harrison DJ, Kunkler IH, Langdon SP.
    Oncotarget; 2017 Jun 27; 8(26):42857-42875. PubMed ID: 28476026
    [Abstract] [Full Text] [Related]

  • 16. JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice.
    Song X, Zhu S, Xie Y, Liu J, Sun L, Zeng D, Wang P, Ma X, Kroemer G, Bartlett DL, Billiar TR, Lotze MT, Zeh HJ, Kang R, Tang D.
    Gastroenterology; 2018 Apr 27; 154(5):1480-1493. PubMed ID: 29248440
    [Abstract] [Full Text] [Related]

  • 17. Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths.
    Swietach P, Wigfield S, Cobden P, Supuran CT, Harris AL, Vaughan-Jones RD.
    J Biol Chem; 2008 Jul 18; 283(29):20473-83. PubMed ID: 18482982
    [Abstract] [Full Text] [Related]

  • 18. Evaluation of CAIX and CAXII Expression in Breast Cancer at Varied O2 Levels: CAIX is the Superior Surrogate Imaging Biomarker of Tumor Hypoxia.
    Tafreshi NK, Lloyd MC, Proemsey JB, Bui MM, Kim J, Gillies RJ, Morse DL.
    Mol Imaging Biol; 2016 Apr 18; 18(2):219-31. PubMed ID: 26276155
    [Abstract] [Full Text] [Related]

  • 19. Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells.
    Silagi ES, Schoepflin ZR, Seifert EL, Merceron C, Schipani E, Shapiro IM, Risbud MV.
    J Bone Miner Res; 2018 Feb 18; 33(2):338-355. PubMed ID: 28940640
    [Abstract] [Full Text] [Related]

  • 20. Expression of carbonic anhydrase IX is associated with poor prognosis through regulation of the epithelial‑mesenchymal transition in hepatocellular carcinoma.
    Hyuga S, Wada H, Eguchi H, Otsuru T, Iwgami Y, Yamada D, Noda T, Asaoka T, Kawamoto K, Gotoh K, Takeda Y, Tanemura M, Umeshita K, Doki Y, Mori M.
    Int J Oncol; 2017 Oct 18; 51(4):1179-1190. PubMed ID: 28849188
    [Abstract] [Full Text] [Related]

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