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Journal Abstract Search

222 related items for PubMed ID: 28107521

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  • 4. Tankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin Puncta.
    Martino-Echarri E, Brocardo MG, Mills KM, Henderson BR.
    PLoS One; 2016; 11(3):e0150484. PubMed ID: 26930278
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  • 6. Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells.
    Ma L, Wang X, Jia T, Wei W, Chua MS, So S.
    Oncotarget; 2015 Sep 22; 6(28):25390-401. PubMed ID: 26246473
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  • 7. Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines.
    Wang W, Liu P, Lavrijsen M, Li S, Zhang R, Li S, van de Geer WS, van de Werken HJG, Peppelenbosch MP, Smits R.
    Sci Rep; 2021 Apr 02; 11(1):7470. PubMed ID: 33811251
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  • 8. Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex.
    Li VS, Ng SS, Boersema PJ, Low TY, Karthaus WR, Gerlach JP, Mohammed S, Heck AJ, Maurice MM, Mahmoudi T, Clevers H.
    Cell; 2012 Jun 08; 149(6):1245-56. PubMed ID: 22682247
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  • 9. The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2.
    Croy HE, Fuller CN, Giannotti J, Robinson P, Foley AVA, Yamulla RJ, Cosgriff S, Greaves BD, von Kleeck RA, An HH, Powers CM, Tran JK, Tocker AM, Jacob KD, Davis BK, Roberts DM.
    J Biol Chem; 2016 Jun 10; 291(24):12747-12760. PubMed ID: 27068743
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  • 10. Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling.
    Callow MG, Tran H, Phu L, Lau T, Lee J, Sandoval WN, Liu PS, Bheddah S, Tao J, Lill JR, Hongo JA, Davis D, Kirkpatrick DS, Polakis P, Costa M.
    PLoS One; 2011 Jun 10; 6(7):e22595. PubMed ID: 21799911
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  • 11. A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.
    Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S.
    Cancer Res; 2012 Jun 01; 72(11):2822-32. PubMed ID: 22440753
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  • 12. Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.
    Koirala S, Klein J, Zheng Y, Glenn NO, Eisemann T, Fon Tacer K, Miller DJ, Kulak O, Lu M, Finkelstein DB, Neale G, Tillman H, Vogel P, Strand DW, Lum L, Brautigam CA, Pascal JM, Clements WK, Potts PR.
    Cell Rep; 2020 Jul 21; 32(3):107922. PubMed ID: 32698014
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  • 13. Targeting Tankyrase to Fight WNT-dependent Tumours.
    Thorvaldsen TE.
    Basic Clin Pharmacol Toxicol; 2017 Aug 21; 121(2):81-88. PubMed ID: 28371398
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  • 14. APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.
    Tanaka N, Mashima T, Mizutani A, Sato A, Aoyama A, Gong B, Yoshida H, Muramatsu Y, Nakata K, Matsuura M, Katayama R, Nagayama S, Fujita N, Sugimoto Y, Seimiya H.
    Mol Cancer Ther; 2017 Apr 21; 16(4):752-762. PubMed ID: 28179481
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  • 15. Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells.
    Bao R, Christova T, Song S, Angers S, Yan X, Attisano L.
    PLoS One; 2012 Apr 21; 7(11):e48670. PubMed ID: 23144924
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  • 16. Coordinated action of Axin1 and Axin2 suppresses β-catenin to regulate muscle stem cell function.
    Figeac N, Zammit PS.
    Cell Signal; 2015 Aug 21; 27(8):1652-65. PubMed ID: 25866367
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  • 17. Wnt signalling induces accumulation of phosphorylated β-catenin in two distinct cytosolic complexes.
    Gerlach JP, Emmink BL, Nojima H, Kranenburg O, Maurice MM.
    Open Biol; 2014 Nov 21; 4(11):140120. PubMed ID: 25392450
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  • 18. RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.
    Mizutani A, Yashiroda Y, Muramatsu Y, Yoshida H, Chikada T, Tsumura T, Okue M, Shirai F, Fukami T, Yoshida M, Seimiya H.
    Cancer Sci; 2018 Dec 21; 109(12):4003-4014. PubMed ID: 30238564
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