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Journal Abstract Search


222 related items for PubMed ID: 28107521

  • 21. Tankyrase Sterile α Motif Domain Polymerization Is Required for Its Role in Wnt Signaling.
    Riccio AA, McCauley M, Langelier MF, Pascal JM.
    Structure; 2016 Sep 06; 24(9):1573-81. PubMed ID: 27499439
    [Abstract] [Full Text] [Related]

  • 22. An aggregon in conductin/axin2 regulates Wnt/β-catenin signaling and holds potential for cancer therapy.
    Bernkopf DB, Brückner M, Hadjihannas MV, Behrens J.
    Nat Commun; 2019 Sep 18; 10(1):4251. PubMed ID: 31534175
    [Abstract] [Full Text] [Related]

  • 23. The Anti-Tumor Activity of Succinyl Macrolactin A Is Mediated through the β-Catenin Destruction Complex via the Suppression of Tankyrase and PI3K/Akt.
    Regmi SC, Park SY, Kim SJ, Banskota S, Shah S, Kim DH, Kim JA.
    PLoS One; 2015 Sep 18; 10(11):e0141753. PubMed ID: 26544726
    [Abstract] [Full Text] [Related]

  • 24. Evidence for tankyrases as antineoplastic targets in lung cancer.
    Busch AM, Johnson KC, Stan RV, Sanglikar A, Ahmed Y, Dmitrovsky E, Freemantle SJ.
    BMC Cancer; 2013 Apr 28; 13():211. PubMed ID: 23621985
    [Abstract] [Full Text] [Related]

  • 25. Thr160 of Axin1 is critical for the formation and function of the β-catenin destruction complex.
    Koyama-Nasu R, Hayashi T, Nasu-Nishimura Y, Akiyama T, Yamanaka R.
    Biochem Biophys Res Commun; 2015 Apr 10; 459(3):411-5. PubMed ID: 25735981
    [Abstract] [Full Text] [Related]

  • 26. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.
    Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F.
    Nature; 2009 Oct 01; 461(7264):614-20. PubMed ID: 19759537
    [Abstract] [Full Text] [Related]

  • 27. Wnt/β-catenin signaling via Axin2 is required for myogenesis and, together with YAP/Taz and Tead1, active in IIa/IIx muscle fibers.
    Huraskin D, Eiber N, Reichel M, Zidek LM, Kravic B, Bernkopf D, von Maltzahn J, Behrens J, Hashemolhosseini S.
    Development; 2016 Sep 01; 143(17):3128-42. PubMed ID: 27578179
    [Abstract] [Full Text] [Related]

  • 28. CCAAT/enhancer-binding protein-β functions as a negative regulator of Wnt/β-catenin signaling through activation of AXIN1 gene expression.
    Park S, Lee MS, Gwak J, Choi TI, Lee Y, Ju BG, Kim CH, Oh S.
    Cell Death Dis; 2018 Oct 03; 9(10):1023. PubMed ID: 30283086
    [Abstract] [Full Text] [Related]

  • 29. Cell cycle control of Wnt/β-catenin signalling by conductin/axin2 through CDC20.
    Hadjihannas MV, Bernkopf DB, Brückner M, Behrens J.
    EMBO Rep; 2012 Apr 03; 13(4):347-54. PubMed ID: 22322943
    [Abstract] [Full Text] [Related]

  • 30. USP25 regulates Wnt signaling by controlling the stability of tankyrases.
    Xu D, Liu J, Fu T, Shan B, Qian L, Pan L, Yuan J.
    Genes Dev; 2017 May 15; 31(10):1024-1035. PubMed ID: 28619731
    [Abstract] [Full Text] [Related]

  • 31. mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer.
    Mashima T, Taneda Y, Jang MK, Mizutani A, Muramatsu Y, Yoshida H, Sato A, Tanaka N, Sugimoto Y, Seimiya H.
    Oncotarget; 2017 Jul 18; 8(29):47902-47915. PubMed ID: 28615517
    [Abstract] [Full Text] [Related]

  • 32. TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer.
    Solberg NT, Waaler J, Lund K, Mygland L, Olsen PA, Krauss S.
    Mol Cancer Res; 2018 Mar 18; 16(3):543-553. PubMed ID: 29222171
    [Abstract] [Full Text] [Related]

  • 33. Discovery of a Novel Triazolopyridine Derivative as a Tankyrase Inhibitor.
    Ryu H, Nam KY, Kim HJ, Song JY, Hwang SG, Kim JS, Kim J, Ahn J.
    Int J Mol Sci; 2021 Jul 08; 22(14):. PubMed ID: 34298950
    [Abstract] [Full Text] [Related]

  • 34. Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.
    Waaler J, Mygland L, Tveita A, Strand MF, Solberg NT, Olsen PA, Aizenshtadt A, Fauskanger M, Lund K, Brinch SA, Lycke M, Dybing E, Nygaard V, Bøe SL, Heintz KM, Hovig E, Hammarström C, Corthay A, Krauss S.
    Commun Biol; 2020 Apr 24; 3(1):196. PubMed ID: 32332858
    [Abstract] [Full Text] [Related]

  • 35. Tankyrase Inhibition Blocks Wnt/β-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer.
    Arqués O, Chicote I, Puig I, Tenbaum SP, Argilés G, Dienstmann R, Fernández N, Caratù G, Matito J, Silberschmidt D, Rodon J, Landolfi S, Prat A, Espín E, Charco R, Nuciforo P, Vivancos A, Shao W, Tabernero J, Palmer HG.
    Clin Cancer Res; 2016 Feb 01; 22(3):644-56. PubMed ID: 26224873
    [Abstract] [Full Text] [Related]

  • 36. Axin1 and Axin2 are regulated by TGF- and mediate cross-talk between TGF- and Wnt signaling pathways.
    Dao DY, Yang X, Chen D, Zuscik M, O'Keefe RJ.
    Ann N Y Acad Sci; 2007 Nov 01; 1116():82-99. PubMed ID: 18083923
    [Abstract] [Full Text] [Related]

  • 37. The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology.
    Norum JH, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, Sørlie T.
    Biol Res; 2018 Jan 09; 51(1):3. PubMed ID: 29316982
    [Abstract] [Full Text] [Related]

  • 38. WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling.
    James RG, Davidson KC, Bosch KA, Biechele TL, Robin NC, Taylor RJ, Major MB, Camp ND, Fowler K, Martins TJ, Moon RT.
    PLoS One; 2012 Jan 09; 7(12):e50457. PubMed ID: 23227175
    [Abstract] [Full Text] [Related]

  • 39. LEF1 and B9L shield β-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors.
    de la Roche M, Ibrahim AE, Mieszczanek J, Bienz M.
    Cancer Res; 2014 Mar 01; 74(5):1495-505. PubMed ID: 24419084
    [Abstract] [Full Text] [Related]

  • 40. Human Cytomegalovirus Inhibits the PARsylation Activity of Tankyrase--A Potential Strategy for Suppression of the Wnt Pathway.
    Roy S, Liu F, Arav-Boger R.
    Viruses; 2015 Dec 29; 8(1):. PubMed ID: 26729153
    [Abstract] [Full Text] [Related]


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