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174 related items for PubMed ID: 28116619

  • 1. HDAC6 regulates sensitivity to cell death in response to stress and post-stress recovery.
    Ryu HW, Won HR, Lee DH, Kwon SH.
    Cell Stress Chaperones; 2017 Mar; 22(2):253-261. PubMed ID: 28116619
    [Abstract] [Full Text] [Related]

  • 2. JNK1 mediates degradation HIF-1alpha by a VHL-independent mechanism that involves the chaperones Hsp90/Hsp70.
    Zhang D, Li J, Costa M, Gao J, Huang C.
    Cancer Res; 2010 Jan 15; 70(2):813-23. PubMed ID: 20068160
    [Abstract] [Full Text] [Related]

  • 3. Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.
    Schoepflin ZR, Shapiro IM, Risbud MV.
    J Bone Miner Res; 2016 Jun 15; 31(6):1287-99. PubMed ID: 26765925
    [Abstract] [Full Text] [Related]

  • 4. Arsenite stabilizes HIF-1α protein through p85α-mediated up-regulation of inducible Hsp70 protein expression.
    Guo W, Yang Z, Xia Q, Liu J, Yu Y, Li J, Zuo Z, Zhang D, Li X, Shi X, Huang C.
    Cell Mol Life Sci; 2011 Feb 15; 68(3):475-88. PubMed ID: 20835880
    [Abstract] [Full Text] [Related]

  • 5. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.
    Zhou J, Schmid T, Frank R, Brüne B.
    J Biol Chem; 2004 Apr 02; 279(14):13506-13. PubMed ID: 14726529
    [Abstract] [Full Text] [Related]

  • 6. Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90.
    Trisciuoglio D, Gabellini C, Desideri M, Ziparo E, Zupi G, Del Bufalo D.
    PLoS One; 2010 Jul 27; 5(7):e11772. PubMed ID: 20668552
    [Abstract] [Full Text] [Related]

  • 7. Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha.
    Kong X, Lin Z, Liang D, Fath D, Sang N, Caro J.
    Mol Cell Biol; 2006 Mar 27; 26(6):2019-28. PubMed ID: 16507982
    [Abstract] [Full Text] [Related]

  • 8. DNA-dependent protein kinase is involved in heat shock protein-mediated accumulation of hypoxia-inducible factor-1alpha in hypoxic preconditioned HepG2 cells.
    Kang MJ, Jung SM, Kim MJ, Bae JH, Kim HB, Kim JY, Park SJ, Song HS, Kim DW, Kang CD, Kim SH.
    FEBS J; 2008 Dec 27; 275(23):5969-81. PubMed ID: 19021771
    [Abstract] [Full Text] [Related]

  • 9. HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness.
    Leyk J, Daly C, Janssen-Bienhold U, Kennedy BN, Richter-Landsberg C.
    Cell Death Dis; 2017 Aug 31; 8(8):e3028. PubMed ID: 29048427
    [Abstract] [Full Text] [Related]

  • 10. Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization.
    Katschinski DM, Le L, Schindler SG, Thomas T, Voss AK, Wenger RH.
    Cell Physiol Biochem; 2004 Aug 31; 14(4-6):351-60. PubMed ID: 15319539
    [Abstract] [Full Text] [Related]

  • 11. AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol.
    Chen S, Yin C, Lao T, Liang D, He D, Wang C, Sang N.
    Cell Cycle; 2015 Aug 03; 14(15):2520-36. PubMed ID: 26061431
    [Abstract] [Full Text] [Related]

  • 12. Posttranslational modification and beyond: interplay between histone deacetylase 6 and heat-shock protein 90.
    Liu P, Xiao J, Wang Y, Song X, Huang L, Ren Z, Kitazato K, Wang Y.
    Mol Med; 2021 Sep 16; 27(1):110. PubMed ID: 34530730
    [Abstract] [Full Text] [Related]

  • 13. Degradation of HIF-1alpha under hypoxia combined with induction of Hsp90 polyubiquitination in cancer cells by hypericin: a unique cancer therapy.
    Barliya T, Mandel M, Livnat T, Weinberger D, Lavie G.
    PLoS One; 2011 Sep 16; 6(9):e22849. PubMed ID: 21949677
    [Abstract] [Full Text] [Related]

  • 14. Ηypoxia-inducible factor-1α, von Hippel-Lindau protein, and heat shock protein expression in ophthalmic pterygium and normal conjunctiva.
    Pagoulatos D, Pharmakakis N, Lakoumentas J, Assimakopoulou M.
    Mol Vis; 2014 Sep 16; 20():441-57. PubMed ID: 24715760
    [Abstract] [Full Text] [Related]

  • 15. Analysis of Expression and Functions of Histone Deacetylase 6 (HDAC6).
    Li M, Zhuang Y, Shan B.
    Methods Mol Biol; 2016 Sep 16; 1436():85-94. PubMed ID: 27246209
    [Abstract] [Full Text] [Related]

  • 16. Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: role of Hsp70 in HIF-1α degradation.
    Gogate SS, Fujita N, Skubutyte R, Shapiro IM, Risbud MV.
    J Bone Miner Res; 2012 May 16; 27(5):1106-17. PubMed ID: 22322648
    [Abstract] [Full Text] [Related]

  • 17. C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway.
    Kataria N, Martinez CA, Kerr B, Zaiter SS, Morgan M, McAlpine SR, Cook KM.
    Cell Physiol Biochem; 2019 May 16; 53(3):480-495. PubMed ID: 31486323
    [Abstract] [Full Text] [Related]

  • 18. HIF-1α-induced HSP70 regulates anabolic responses in articular chondrocytes under hypoxic conditions.
    Tsuchida S, Arai Y, Takahashi KA, Kishida T, Terauchi R, Honjo K, Nakagawa S, Inoue H, Ikoma K, Ueshima K, Matsuki T, Mazda O, Kubo T.
    J Orthop Res; 2014 Aug 16; 32(8):975-80. PubMed ID: 24677016
    [Abstract] [Full Text] [Related]

  • 19. Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1.
    Yoo YG, Kong G, Lee MO.
    EMBO J; 2006 Mar 22; 25(6):1231-41. PubMed ID: 16511565
    [Abstract] [Full Text] [Related]

  • 20. Tubastatin ameliorates pulmonary fibrosis by targeting the TGFβ-PI3K-Akt pathway.
    Saito S, Zhuang Y, Shan B, Danchuk S, Luo F, Korfei M, Guenther A, Lasky JA.
    PLoS One; 2017 Mar 22; 12(10):e0186615. PubMed ID: 29045477
    [Abstract] [Full Text] [Related]


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