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Journal Abstract Search


379 related items for PubMed ID: 28131631

  • 1. Ryanodine receptor modification and regulation by intracellular Ca2+ and Mg2+ in healthy and failing human hearts.
    Walweel K, Molenaar P, Imtiaz MS, Denniss A, Dos Remedios C, van Helden DF, Dulhunty AF, Laver DR, Beard NA.
    J Mol Cell Cardiol; 2017 Mar; 104():53-62. PubMed ID: 28131631
    [Abstract] [Full Text] [Related]

  • 2. Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts.
    Tateishi H, Yano M, Mochizuki M, Suetomi T, Ono M, Xu X, Uchinoumi H, Okuda S, Oda T, Kobayashi S, Yamamoto T, Ikeda Y, Ohkusa T, Ikemoto N, Matsuzaki M.
    Cardiovasc Res; 2009 Feb 15; 81(3):536-45. PubMed ID: 18996969
    [Abstract] [Full Text] [Related]

  • 3. Dissociation of calmodulin from cardiac ryanodine receptor causes aberrant Ca(2+) release in heart failure.
    Ono M, Yano M, Hino A, Suetomi T, Xu X, Susa T, Uchinoumi H, Tateishi H, Oda T, Okuda S, Doi M, Kobayashi S, Yamamoto T, Koseki N, Kyushiki H, Ikemoto N, Matsuzaki M.
    Cardiovasc Res; 2010 Sep 01; 87(4):609-17. PubMed ID: 20388639
    [Abstract] [Full Text] [Related]

  • 4. Redox modification of ryanodine receptors contributes to sarcoplasmic reticulum Ca2+ leak in chronic heart failure.
    Terentyev D, Györke I, Belevych AE, Terentyeva R, Sridhar A, Nishijima Y, de Blanco EC, Khanna S, Sen CK, Cardounel AJ, Carnes CA, Györke S.
    Circ Res; 2008 Dec 05; 103(12):1466-72. PubMed ID: 19008475
    [Abstract] [Full Text] [Related]

  • 5. The effect of PKA-mediated phosphorylation of ryanodine receptor on SR Ca2+ leak in ventricular myocytes.
    Bovo E, Huke S, Blatter LA, Zima AV.
    J Mol Cell Cardiol; 2017 Mar 05; 104():9-16. PubMed ID: 28131630
    [Abstract] [Full Text] [Related]

  • 6. Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure.
    Ai X, Curran JW, Shannon TR, Bers DM, Pogwizd SM.
    Circ Res; 2005 Dec 09; 97(12):1314-22. PubMed ID: 16269653
    [Abstract] [Full Text] [Related]

  • 7. Enhanced binding of calmodulin to the ryanodine receptor corrects contractile dysfunction in failing hearts.
    Hino A, Yano M, Kato T, Fukuda M, Suetomi T, Ono M, Murakami W, Susa T, Okuda S, Doi M, Kobayashi S, Yamamoto T, Koseki N, Kyushiki H, Ikemoto N, Matsuzaki M.
    Cardiovasc Res; 2012 Dec 01; 96(3):433-43. PubMed ID: 22893680
    [Abstract] [Full Text] [Related]

  • 8. Limitations of FKBP12.6-directed treatment strategies for maladaptive cardiac remodeling and heart failure.
    Seidler T, Teucher N, Hellenkamp K, Unsöld B, Grebe C, Kramps P, Schotola H, Wagner S, Schöndube FA, Hasenfuss G, Maier LS.
    J Mol Cell Cardiol; 2011 Jan 01; 50(1):33-42. PubMed ID: 20797399
    [Abstract] [Full Text] [Related]

  • 9. Phenytoin Reduces Activity of Cardiac Ryanodine Receptor 2; A Potential Mechanism for Its Cardioprotective Action.
    Ashna A, van Helden DF, Dos Remedios C, Molenaar P, Laver DR.
    Mol Pharmacol; 2020 Apr 01; 97(4):250-258. PubMed ID: 32015008
    [Abstract] [Full Text] [Related]

  • 10. Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814.
    Walweel K, Gomez-Hurtado N, Rebbeck RT, Oo YW, Beard NA, Molenaar P, Dos Remedios C, van Helden DF, Cornea RL, Knollmann BC, Laver DR.
    J Mol Cell Cardiol; 2019 May 01; 130():96-106. PubMed ID: 30928430
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  • 12. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts.
    Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR.
    Cell; 2000 May 12; 101(4):365-76. PubMed ID: 10830164
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  • 15. S100A1 DNA-based Inotropic Therapy Protects Against Proarrhythmogenic Ryanodine Receptor 2 Dysfunction.
    Ritterhoff J, Völkers M, Seitz A, Spaich K, Gao E, Peppel K, Pleger ST, Zimmermann WH, Friedrich O, Fink RHA, Koch WJ, Katus HA, Most P.
    Mol Ther; 2015 Aug 12; 23(8):1320-1330. PubMed ID: 26005840
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  • 17. Conditional FKBP12.6 overexpression in mouse cardiac myocytes prevents triggered ventricular tachycardia through specific alterations in excitation-contraction coupling.
    Gellen B, Fernández-Velasco M, Briec F, Vinet L, LeQuang K, Rouet-Benzineb P, Bénitah JP, Pezet M, Palais G, Pellegrin N, Zhang A, Perrier R, Escoubet B, Marniquet X, Richard S, Jaisser F, Gómez AM, Charpentier F, Mercadier JJ.
    Circulation; 2008 Apr 08; 117(14):1778-86. PubMed ID: 18378612
    [Abstract] [Full Text] [Related]

  • 18. TRIC-A Channel Maintains Store Calcium Handling by Interacting With Type 2 Ryanodine Receptor in Cardiac Muscle.
    Zhou X, Park KH, Yamazaki D, Lin PH, Nishi M, Ma Z, Qiu L, Murayama T, Zou X, Takeshima H, Zhou J, Ma J.
    Circ Res; 2020 Feb 14; 126(4):417-435. PubMed ID: 31805819
    [Abstract] [Full Text] [Related]

  • 19. Ryanodine receptor 2 inhibition reduces dispersion of cardiac repolarization, improves contractile function, and prevents sudden arrhythmic death in failing hearts.
    Joshi P, Estes S, DeMazumder D, Knollmann BC, Dey S.
    Elife; 2023 Dec 11; 12():. PubMed ID: 38078905
    [Abstract] [Full Text] [Related]

  • 20. CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift.
    Uchinoumi H, Yang Y, Oda T, Li N, Alsina KM, Puglisi JL, Chen-Izu Y, Cornea RL, Wehrens XHT, Bers DM.
    J Mol Cell Cardiol; 2016 Sep 11; 98():62-72. PubMed ID: 27318036
    [Abstract] [Full Text] [Related]


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