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Journal Abstract Search

234 related items for PubMed ID: 28153829

  • 1. Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling.
    Chen CW, Beyer C, Liu J, Maier C, Li C, Trinh-Minh T, Xu X, Cole SH, Hsieh MH, Ng N, Althage A, Meeusen S, Pan S, Svensson EC, Seidel HM, Schett G, Gergely P, Harris JL, Distler JH.
    Ann Rheum Dis; 2017 Apr; 76(4):773-778. PubMed ID: 28153829
    [Abstract] [Full Text] [Related]

  • 2. Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis.
    Tomcik M, Zerr P, Pitkowski J, Palumbo-Zerr K, Avouac J, Distler O, Becvar R, Senolt L, Schett G, Distler JH.
    Ann Rheum Dis; 2014 Jun; 73(6):1215-22. PubMed ID: 23661493
    [Abstract] [Full Text] [Related]

  • 3. Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis.
    Huang J, Beyer C, Palumbo-Zerr K, Zhang Y, Ramming A, Distler A, Gelse K, Distler O, Schett G, Wollin L, Distler JH.
    Ann Rheum Dis; 2016 May; 75(5):883-90. PubMed ID: 25858641
    [Abstract] [Full Text] [Related]

  • 4. Spleen tyrosine kinase (Syk) inhibitor fostamatinib limits tissue damage and fibrosis in a bleomycin-induced scleroderma mouse model.
    Pamuk ON, Can G, Ayvaz S, Karaca T, Pamuk GE, Demirtas S, Tsokos GC.
    Clin Exp Rheumatol; 2015 May; 33(4 Suppl 91):S15-22. PubMed ID: 26148346
    [Abstract] [Full Text] [Related]

  • 5. The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc.
    Liang R, Šumová B, Cordazzo C, Mallano T, Zhang Y, Wohlfahrt T, Dees C, Ramming A, Krasowska D, Michalska-Jakubus M, Distler O, Schett G, Šenolt L, Distler JH.
    Ann Rheum Dis; 2017 Apr; 76(4):756-764. PubMed ID: 27793816
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.
    Zhang Y, Dees C, Beyer C, Lin NY, Distler A, Zerr P, Palumbo K, Susok L, Kreuter A, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2015 May; 74(5):936-43. PubMed ID: 24431397
    [Abstract] [Full Text] [Related]

  • 7. Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability.
    Distler A, Lang V, Del Vecchio T, Huang J, Zhang Y, Beyer C, Lin NY, Palumbo-Zerr K, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2014 Jun; 73(6):1264-8. PubMed ID: 24445254
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis.
    Horn A, Kireva T, Palumbo-Zerr K, Dees C, Tomcik M, Cordazzo C, Zerr P, Akhmetshina A, Ruat M, Distler O, Beyer C, Schett G, Distler JH.
    Ann Rheum Dis; 2012 May; 71(5):785-9. PubMed ID: 22402139
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of phosphodiesterase 4 (PDE4) reduces dermal fibrosis by interfering with the release of interleukin-6 from M2 macrophages.
    Maier C, Ramming A, Bergmann C, Weinkam R, Kittan N, Schett G, Distler JHW, Beyer C.
    Ann Rheum Dis; 2017 Jun; 76(6):1133-1141. PubMed ID: 28209630
    [Abstract] [Full Text] [Related]

  • 10. Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis.
    Beyer C, Reichert H, Akan H, Mallano T, Schramm A, Dees C, Palumbo-Zerr K, Lin NY, Distler A, Gelse K, Varga J, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2013 Jul; 72(7):1255-8. PubMed ID: 23595143
    [Abstract] [Full Text] [Related]

  • 11. X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc).
    Bergmann C, Hallenberger L, Chenguiti Fakhouri S, Merlevede B, Brandt A, Dees C, Zhu H, Zehender A, Zhou X, Schwab A, Chen CW, Györfi AH, Matei AE, Chakraborty D, Trinh-Minh T, Rauber S, Coras R, Bozec A, Kreuter A, Ziemer M, Schett G, Distler JHW.
    Ann Rheum Dis; 2021 Aug; 80(8):1048-1056. PubMed ID: 33903093
    [Abstract] [Full Text] [Related]

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  • 13. Vitamin D receptor regulates TGF-β signalling in systemic sclerosis.
    Zerr P, Vollath S, Palumbo-Zerr K, Tomcik M, Huang J, Distler A, Beyer C, Dees C, Gela K, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2015 Mar; 74(3):e20. PubMed ID: 24448349
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of glycogen synthase kinase 3β induces dermal fibrosis by activation of the canonical Wnt pathway.
    Bergmann C, Akhmetshina A, Dees C, Palumbo K, Zerr P, Beyer C, Zwerina J, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2011 Dec; 70(12):2191-8. PubMed ID: 21873331
    [Abstract] [Full Text] [Related]

  • 15. The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis.
    Avouac J, Palumbo-Zerr K, Ruzehaji N, Tomcik M, Zerr P, Dees C, Distler A, Beyer C, Schneider H, Distler O, Schett G, Allanore Y, Distler JH.
    Arthritis Rheumatol; 2014 Nov; 66(11):3140-50. PubMed ID: 25155144
    [Abstract] [Full Text] [Related]

  • 16. Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis.
    Tomcik M, Palumbo-Zerr K, Zerr P, Sumova B, Avouac J, Dees C, Distler A, Becvar R, Distler O, Schett G, Senolt L, Distler JH.
    Ann Rheum Dis; 2016 Mar; 75(3):609-16. PubMed ID: 25603829
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  • 18. Inactivation of evenness interrupted (EVI) reduces experimental fibrosis by combined inhibition of canonical and non-canonical Wnt signalling.
    Distler A, Ziemer C, Beyer C, Lin NY, Chen CW, Palumbo-Zerr K, Dees C, Weidemann A, Distler O, Schett G, Distler JH.
    Ann Rheum Dis; 2014 Mar; 73(3):624-7. PubMed ID: 24257024
    [Abstract] [Full Text] [Related]

  • 19. Dipeptidylpeptidase 4 as a Marker of Activated Fibroblasts and a Potential Target for the Treatment of Fibrosis in Systemic Sclerosis.
    Soare A, Györfi HA, Matei AE, Dees C, Rauber S, Wohlfahrt T, Chen CW, Ludolph I, Horch RE, Bäuerle T, von Hörsten S, Mihai C, Distler O, Ramming A, Schett G, Distler JHW.
    Arthritis Rheumatol; 2020 Jan; 72(1):137-149. PubMed ID: 31350829
    [Abstract] [Full Text] [Related]

  • 20. Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma.
    Sonnylal S, Denton CP, Zheng B, Keene DR, He R, Adams HP, Vanpelt CS, Geng YJ, Deng JM, Behringer RR, de Crombrugghe B.
    Arthritis Rheum; 2007 Jan; 56(1):334-44. PubMed ID: 17195237
    [Abstract] [Full Text] [Related]

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