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319 related items for PubMed ID: 28154184

  • 1. Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
    Gillissen B, Richter A, Richter A, Preissner R, Schulze-Osthoff K, Essmann F, Daniel PT.
    J Biol Chem; 2017 Apr 21; 292(16):6478-6492. PubMed ID: 28154184
    [Abstract] [Full Text] [Related]

  • 2. The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation.
    Rosato RR, Almenara JA, Coe S, Grant S.
    Cancer Res; 2007 Oct 01; 67(19):9490-500. PubMed ID: 17909059
    [Abstract] [Full Text] [Related]

  • 3. Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.
    Meng XW, Lee SH, Dai H, Loegering D, Yu C, Flatten K, Schneider P, Dai NT, Kumar SK, Smith BD, Karp JE, Adjei AA, Kaufmann SH.
    J Biol Chem; 2007 Oct 12; 282(41):29831-46. PubMed ID: 17698840
    [Abstract] [Full Text] [Related]

  • 4. Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK.
    Ling YH, Lin R, Perez-Soler R.
    Mol Pharmacol; 2008 Sep 12; 74(3):793-806. PubMed ID: 18524889
    [Abstract] [Full Text] [Related]

  • 5. Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells.
    Huang S, Sinicrope FA.
    Mol Cancer Ther; 2010 Mar 12; 9(3):742-50. PubMed ID: 20197401
    [Abstract] [Full Text] [Related]

  • 6. Targeted therapy of the XIAP/proteasome pathway overcomes TRAIL-resistance in carcinoma by switching apoptosis signaling to a Bax/Bak-independent 'type I' mode.
    Gillissen B, Richter A, Richter A, Overkamp T, Essmann F, Hemmati PG, Preissner R, Belka C, Daniel PT.
    Cell Death Dis; 2013 May 23; 4(5):e643. PubMed ID: 23703388
    [Abstract] [Full Text] [Related]

  • 7. Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.
    Izeradjene K, Douglas L, Tillman DM, Delaney AB, Houghton JA.
    Cancer Res; 2005 Aug 15; 65(16):7436-45. PubMed ID: 16103097
    [Abstract] [Full Text] [Related]

  • 8. Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.
    Gillissen B, Wendt J, Richter A, Richter A, Müer A, Overkamp T, Gebhardt N, Preissner R, Belka C, Dörken B, Daniel PT.
    J Cell Biol; 2010 Mar 22; 188(6):851-62. PubMed ID: 20308427
    [Abstract] [Full Text] [Related]

  • 9. Survivin inhibitor YM-155 sensitizes tumor necrosis factor- related apoptosis-inducing ligand-resistant glioma cells to apoptosis through Mcl-1 downregulation and by engaging the mitochondrial death pathway.
    Premkumar DR, Jane EP, Foster KA, Pollack IF.
    J Pharmacol Exp Ther; 2013 Aug 22; 346(2):201-10. PubMed ID: 23740602
    [Abstract] [Full Text] [Related]

  • 10. Dicoumarol sensitizes renal cell carcinoma Caki cells to TRAIL-induced apoptosis through down-regulation of Bcl-2, Mcl-1 and c-FLIP in a NQO1-independent manner.
    Park EJ, Min KJ, Choi KS, Kwon TK.
    Exp Cell Res; 2014 Apr 15; 323(1):144-154. PubMed ID: 24462458
    [Abstract] [Full Text] [Related]

  • 11. Synergistic effect of fisetin combined with sorafenib in human cervical cancer HeLa cells through activation of death receptor-5 mediated caspase-8/caspase-3 and the mitochondria-dependent apoptotic pathway.
    Lin MT, Lin CL, Lin TY, Cheng CW, Yang SF, Lin CL, Wu CC, Hsieh YH, Tsai JP.
    Tumour Biol; 2016 May 15; 37(5):6987-96. PubMed ID: 26662956
    [Abstract] [Full Text] [Related]

  • 12. Fas-induced apoptosis of renal cell carcinoma is mediated by apoptosis signal-regulating kinase 1 via mitochondrial damage-dependent caspase-8 activation.
    Hassan M, Feyen O, Grinstein E.
    Cell Oncol; 2009 May 15; 31(6):437-56. PubMed ID: 19940360
    [Abstract] [Full Text] [Related]

  • 13. MiRNA-30a-mediated autophagy inhibition sensitizes renal cell carcinoma cells to sorafenib.
    Zheng B, Zhu H, Gu D, Pan X, Qian L, Xue B, Yang D, Zhou J, Shan Y.
    Biochem Biophys Res Commun; 2015 Apr 03; 459(2):234-239. PubMed ID: 25712526
    [Abstract] [Full Text] [Related]

  • 14. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells.
    Gillespie S, Borrow J, Zhang XD, Hersey P.
    Apoptosis; 2006 Dec 03; 11(12):2251-65. PubMed ID: 17051334
    [Abstract] [Full Text] [Related]

  • 15. Artesunate induces apoptosis via a ROS-independent and Bax-mediated intrinsic pathway in HepG2 cells.
    Qin G, Wu L, Liu H, Pang Y, Zhao C, Wu S, Wang X, Chen T.
    Exp Cell Res; 2015 Aug 15; 336(2):308-17. PubMed ID: 26163896
    [Abstract] [Full Text] [Related]

  • 16. 6-Shogaol enhances renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated cytochrome c release and down-regulation of c-FLIP(L) expression.
    Han MA, Woo SM, Min KJ, Kim S, Park JW, Kim DE, Kim SH, Choi YH, Kwon TK.
    Chem Biol Interact; 2015 Feb 25; 228():69-78. PubMed ID: 25619640
    [Abstract] [Full Text] [Related]

  • 17. The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.
    Sung ES, Park KJ, Choi HJ, Kim CH, Kim YS.
    Exp Cell Res; 2012 Aug 01; 318(13):1564-76. PubMed ID: 22513214
    [Abstract] [Full Text] [Related]

  • 18. Oxaliplatin sensitizes human colon cancer cells to TRAIL through JNK-dependent phosphorylation of Bcl-xL.
    El Fajoui Z, Toscano F, Jacquemin G, Abello J, Scoazec JY, Micheau O, Saurin JC.
    Gastroenterology; 2011 Aug 01; 141(2):663-73. PubMed ID: 21683075
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP.
    Seo BR, Min KJ, Woo SM, Choe M, Choi KS, Lee YK, Yoon G, Kwon TK.
    Antioxid Redox Signal; 2017 Aug 01; 27(4):215-233. PubMed ID: 27927016
    [Abstract] [Full Text] [Related]

  • 20. ROS mediated ER stress induces Bax-Bak dependent and independent apoptosis in response to Thioridazine.
    Seervi M, Rani A, Sharma AK, Santhosh Kumar TR.
    Biomed Pharmacother; 2018 Oct 01; 106():200-209. PubMed ID: 29960166
    [Abstract] [Full Text] [Related]

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