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319 related items for PubMed ID: 28154184
41. Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis. Huang K, Zhang J, O'Neill KL, Gurumurthy CB, Quadros RM, Tu Y, Luo X. J Biol Chem; 2016 May 27; 291(22):11843-51. PubMed ID: 27053107 [Abstract] [Full Text] [Related]
42. Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells. Choi SY, Kim MJ, Kang CM, Bae S, Cho CK, Soh JW, Kim JH, Kang S, Chung HY, Lee YS, Lee SJ. J Biol Chem; 2006 Mar 17; 281(11):7049-59. PubMed ID: 16410245 [Abstract] [Full Text] [Related]
43. Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction. Seo SK, Lee HC, Woo SH, Jin HO, Yoo DH, Lee SJ, An S, Choe TB, Park MJ, Hong SI, Park IC, Rhee CH. Apoptosis; 2007 Jan 17; 12(1):195-209. PubMed ID: 17136320 [Abstract] [Full Text] [Related]
44. The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilization. Brüning A, Rahmeh M, Gingelmaier A, Friese K. Mol Cancer; 2010 Jan 27; 9():19. PubMed ID: 20105315 [Abstract] [Full Text] [Related]
45. Resveratrol attenuates constitutive STAT3 and STAT5 activation through induction of PTPε and SHP-2 tyrosine phosphatases and potentiates sorafenib-induced apoptosis in renal cell carcinoma. Kim C, Baek SH, Um JY, Shim BS, Ahn KS. BMC Nephrol; 2016 Feb 25; 17():19. PubMed ID: 26911335 [Abstract] [Full Text] [Related]
46. Sorafenib inhibits ERK1/2 and MCL-1(L) phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma. Katz SI, Zhou L, Chao G, Smith CD, Ferrara T, Wang W, Dicker DT, El-Deiry WS. Cancer Biol Ther; 2009 Dec 25; 8(24):2406-16. PubMed ID: 20038816 [Abstract] [Full Text] [Related]
47. Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis. Abdulghani J, Allen JE, Dicker DT, Liu YY, Goldenberg D, Smith CD, Humphreys R, El-Deiry WS. PLoS One; 2013 Dec 25; 8(9):e75414. PubMed ID: 24086526 [Abstract] [Full Text] [Related]
48. Reactive oxygen species regulate Bax translocation and mitochondrial transmembrane potential, a possible mechanism for enhanced TRAIL-induced apoptosis by CCCP. Chaudhari AA, Seol JW, Kim SJ, Lee YJ, Kang HS, Kim IS, Kim NS, Park SY. Oncol Rep; 2007 Jul 25; 18(1):71-6. PubMed ID: 17549348 [Abstract] [Full Text] [Related]
49. Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells. Hao JH, Yu M, Liu FT, Newland AC, Jia L. Cancer Res; 2004 May 15; 64(10):3607-16. PubMed ID: 15150119 [Abstract] [Full Text] [Related]
50. Acetylshikonin Sensitizes Hepatocellular Carcinoma Cells to Apoptosis through ROS-Mediated Caspase Activation. Hong M, Li J, Li S, M Almutairi M. Cells; 2019 Nov 19; 8(11):. PubMed ID: 31752383 [Abstract] [Full Text] [Related]
51. FTY720 enhances TRAIL-mediated apoptosis by up-regulating DR5 and down-regulating Mcl-1 in cancer cells. Woo SM, Seo BR, Min KJ, Kwon TK. Oncotarget; 2015 May 10; 6(13):11614-26. PubMed ID: 25843953 [Abstract] [Full Text] [Related]
52. Two death pathways induced by sorafenib in myeloma cells: Puma-mediated apoptosis and necroptosis. Ramírez-Labrada A, López-Royuela N, Jarauta V, Galán-Malo P, Azaceta G, Palomera L, Pardo J, Anel A, Marzo I, Naval J. Clin Transl Oncol; 2015 Feb 10; 17(2):121-32. PubMed ID: 25037851 [Abstract] [Full Text] [Related]
53. Sorafenib and HDAC inhibitors synergize with TRAIL to kill tumor cells. Hamed HA, Yamaguchi Y, Fisher PB, Grant S, Dent P. J Cell Physiol; 2013 Oct 10; 228(10):1996-2005. PubMed ID: 23674352 [Abstract] [Full Text] [Related]
54. YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-κB-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells. Woo SM, Min KJ, Seo BR, Kwon TK. Oncotarget; 2016 Sep 20; 7(38):61520-61532. PubMed ID: 27528031 [Abstract] [Full Text] [Related]
55. Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway. von Haefen C, Gillissen B, Hemmati PG, Wendt J, Güner D, Mrozek A, Belka C, Dörken B, Daniel PT. Oncogene; 2004 Oct 28; 23(50):8320-32. PubMed ID: 15467752 [Abstract] [Full Text] [Related]
56. Long noncoding RNA-SRLR elicits intrinsic sorafenib resistance via evoking IL-6/STAT3 axis in renal cell carcinoma. Xu Z, Yang F, Wei D, Liu B, Chen C, Bao Y, Wu Z, Wu D, Tan H, Li J, Wang J, Liu J, Sun S, Qu L, Wang L. Oncogene; 2017 Apr 06; 36(14):1965-1977. PubMed ID: 27841868 [Abstract] [Full Text] [Related]
57. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53. Zhang J, Huang K, O'Neill KL, Pang X, Luo X. Cell Death Dis; 2016 Jun 16; 7(6):e2266. PubMed ID: 27310874 [Abstract] [Full Text] [Related]
58. The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation. Vince JE, De Nardo D, Gao W, Vince AJ, Hall C, McArthur K, Simpson D, Vijayaraj S, Lindqvist LM, Bouillet P, Rizzacasa MA, Man SM, Silke J, Masters SL, Lessene G, Huang DCS, Gray DHD, Kile BT, Shao F, Lawlor KE. Cell Rep; 2018 Nov 27; 25(9):2339-2353.e4. PubMed ID: 30485804 [Abstract] [Full Text] [Related]
59. 3-Bromopyruvate potentiates TRAIL-induced apoptosis in human colon cancer cells through a reactive oxygen species- and caspase-dependent mitochondrial pathway. Abbaszadeh H, Valizadeh A, Mahdavinia M, Teimoori A, Pipelzadeh MH, Zeidooni L, Alboghobeish S. Can J Physiol Pharmacol; 2019 Dec 27; 97(12):1176-1184. PubMed ID: 31491344 [Abstract] [Full Text] [Related]