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628 related items for PubMed ID: 28161249

  • 1. Inhibitors of nuclease and redox activity of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1).
    Laev SS, Salakhutdinov NF, Lavrik OI.
    Bioorg Med Chem; 2017 May 01; 25(9):2531-2544. PubMed ID: 28161249
    [Abstract] [Full Text] [Related]

  • 2. DNA repair and redox activities and inhibitors of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1): a comparative analysis and their scope and limitations toward anticancer drug development.
    Kaur G, Cholia RP, Mantha AK, Kumar R.
    J Med Chem; 2014 Dec 26; 57(24):10241-56. PubMed ID: 25280182
    [Abstract] [Full Text] [Related]

  • 3. Isolation of a small molecule inhibitor of DNA base excision repair.
    Madhusudan S, Smart F, Shrimpton P, Parsons JL, Gardiner L, Houlbrook S, Talbot DC, Hammonds T, Freemont PA, Sternberg MJ, Dianov GL, Hickson ID.
    Nucleic Acids Res; 2005 Dec 26; 33(15):4711-24. PubMed ID: 16113242
    [Abstract] [Full Text] [Related]

  • 4. The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target.
    Fishel ML, Kelley MR.
    Mol Aspects Med; 2007 Dec 26; 28(3-4):375-95. PubMed ID: 17560642
    [Abstract] [Full Text] [Related]

  • 5. AP Endonuclease 1 as a Key Enzyme in Repair of Apurinic/Apyrimidinic Sites.
    Dyrkheeva NS, Lebedeva NA, Lavrik OI.
    Biochemistry (Mosc); 2016 Sep 26; 81(9):951-67. PubMed ID: 27682167
    [Abstract] [Full Text] [Related]

  • 6. [Multifunctional human apurinic/apyrimidinic endonuclease 1: the role of additional functions].
    Dyrkheeva NS, Khodyreva SN, Lavrik OI.
    Mol Biol (Mosk); 2007 Sep 26; 41(3):450-66. PubMed ID: 17685223
    [Abstract] [Full Text] [Related]

  • 7. Anticancer clinical utility of the apurinic/apyrimidinic endonuclease/redox factor-1 (APE/Ref-1).
    Zhang Y, Wang J.
    Chin J Cancer; 2010 Mar 26; 29(3):333-9. PubMed ID: 20193121
    [Abstract] [Full Text] [Related]

  • 8. NMR studies reveal an unexpected binding site for a redox inhibitor of AP endonuclease 1.
    Manvilla BA, Wauchope O, Seley-Radtke KL, Drohat AC.
    Biochemistry; 2011 Dec 06; 50(48):10540-9. PubMed ID: 22032234
    [Abstract] [Full Text] [Related]

  • 9. Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1.
    Kelley MR, Parsons SH.
    Antioxid Redox Signal; 2001 Aug 06; 3(4):671-83. PubMed ID: 11554453
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone.
    Luo M, Kelley MR.
    Anticancer Res; 2004 Aug 06; 24(4):2127-34. PubMed ID: 15330152
    [Abstract] [Full Text] [Related]

  • 11. The redox function of apurinic/apyrimidinic endonuclease 1 as key modulator in photodynamic therapy.
    Franchi LP, de Freitas Lima JEB, Piva HL, Tedesco AC.
    J Photochem Photobiol B; 2020 Oct 06; 211():111992. PubMed ID: 32805556
    [Abstract] [Full Text] [Related]

  • 12. The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation.
    Kladova OA, Bazlekowa-Karaban M, Baconnais S, Piétrement O, Ishchenko AA, Matkarimov BT, Iakovlev DA, Vasenko A, Fedorova OS, Le Cam E, Tudek B, Kuznetsov NA, Saparbaev M.
    DNA Repair (Amst); 2018 Apr 06; 64():10-25. PubMed ID: 29475157
    [Abstract] [Full Text] [Related]

  • 13. Design and synthesis of novel quinone inhibitors targeted to the redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor-1 (Ape1/ref-1).
    Nyland RL, Luo M, Kelley MR, Borch RF.
    J Med Chem; 2010 Feb 11; 53(3):1200-10. PubMed ID: 20067291
    [Abstract] [Full Text] [Related]

  • 14. Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1.
    Kelley MR, Luo M, Reed A, Su D, Delaplane S, Borch RF, Nyland RL, Gross ML, Georgiadis MM.
    Antioxid Redox Signal; 2011 Apr 15; 14(8):1387-401. PubMed ID: 20874257
    [Abstract] [Full Text] [Related]

  • 15. Chemical Inhibition of Apurinic-Apyrimidinic Endonuclease 1 Redox and DNA Repair Functions Affects the Inflammatory Response via Different but Overlapping Mechanisms.
    Oliveira TT, Fontes-Dantas FL, de Medeiros Oliveira RK, Pinheiro DML, Coutinho LG, da Silva VL, de Souza SJ, Agnez-Lima LF.
    Front Cell Dev Biol; 2021 Apr 15; 9():731588. PubMed ID: 34616737
    [Abstract] [Full Text] [Related]

  • 16. Small-molecule inhibitors of APE1 DNA repair function: an overview.
    Al-Safi RI, Odde S, Shabaik Y, Neamati N.
    Curr Mol Pharmacol; 2012 Jan 15; 5(1):14-35. PubMed ID: 22122462
    [Abstract] [Full Text] [Related]

  • 17. Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 (Ape1/Ref-1) Modulates Antigen Presenting Cell-mediated T Helper Cell Type 1 Responses.
    Akhter N, Takeda Y, Nara H, Araki A, Ishii N, Asao N, Asao H.
    J Biol Chem; 2016 Nov 04; 291(45):23672-23680. PubMed ID: 27637330
    [Abstract] [Full Text] [Related]

  • 18. Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer.
    Kelley MR, Cheng L, Foster R, Tritt R, Jiang J, Broshears J, Koch M.
    Clin Cancer Res; 2001 Apr 04; 7(4):824-30. PubMed ID: 11309329
    [Abstract] [Full Text] [Related]

  • 19. APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.
    Kelley MR, Georgiadis MM, Fishel ML.
    Curr Mol Pharmacol; 2012 Jan 04; 5(1):36-53. PubMed ID: 22122463
    [Abstract] [Full Text] [Related]

  • 20. Pharmacophore guided discovery of small-molecule human apurinic/apyrimidinic endonuclease 1 inhibitors.
    Zawahir Z, Dayam R, Deng J, Pereira C, Neamati N.
    J Med Chem; 2009 Jan 08; 52(1):20-32. PubMed ID: 19072053
    [Abstract] [Full Text] [Related]

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