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Journal Abstract Search

283 related items for PubMed ID: 28182322

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  • 3. On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.
    Patel A, Dharmarajan V, Vought VE, Cosgrove MS.
    J Biol Chem; 2009 Sep 04; 284(36):24242-56. PubMed ID: 19556245
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  • 4. An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain.
    Cao F, Chen Y, Cierpicki T, Liu Y, Basrur V, Lei M, Dou Y.
    PLoS One; 2010 Nov 23; 5(11):e14102. PubMed ID: 21124902
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  • 5. Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.
    Patel A, Vought VE, Swatkoski S, Viggiano S, Howard B, Dharmarajan V, Monteith KE, Kupakuwana G, Namitz KE, Shinsky SA, Cotter RJ, Cosgrove MS.
    J Biol Chem; 2014 Jan 10; 289(2):868-84. PubMed ID: 24235145
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  • 6. Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.
    Alicea-Velázquez NL, Shinsky SA, Loh DM, Lee JH, Skalnik DG, Cosgrove MS.
    J Biol Chem; 2016 Oct 21; 291(43):22357-22372. PubMed ID: 27563068
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  • 9. The internal interaction in RBBP5 regulates assembly and activity of MLL1 methyltransferase complex.
    Han J, Li T, Li Y, Li M, Wang X, Peng C, Su C, Li N, Li Y, Xu Y, Chen Y.
    Nucleic Acids Res; 2019 Nov 04; 47(19):10426-10438. PubMed ID: 31544921
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  • 11. A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex.
    Patel A, Vought VE, Dharmarajan V, Cosgrove MS.
    J Biol Chem; 2011 Feb 04; 286(5):3359-69. PubMed ID: 21106533
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  • 12. Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic.
    Avdic V, Zhang P, Lanouette S, Voronova A, Skerjanc I, Couture JF.
    FASEB J; 2011 Mar 04; 25(3):960-7. PubMed ID: 21135039
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  • 13. Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
    Park SH, Ayoub A, Lee YT, Xu J, Kim H, Zheng W, Zhang B, Sha L, An S, Zhang Y, Cianfrocco MA, Su M, Dou Y, Cho US.
    Nat Commun; 2019 Dec 05; 10(1):5540. PubMed ID: 31804488
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  • 15. Structural basis of nucleosome recognition and modification by MLL methyltransferases.
    Xue H, Yao T, Cao M, Zhu G, Li Y, Yuan G, Chen Y, Lei M, Huang J.
    Nature; 2019 Sep 05; 573(7774):445-449. PubMed ID: 31485071
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  • 16. Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex.
    Shinsky SA, Cosgrove MS.
    J Biol Chem; 2015 Oct 23; 290(43):25819-33. PubMed ID: 26324722
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  • 17. Structural and biochemical insights into MLL1 core complex assembly.
    Avdic V, Zhang P, Lanouette S, Groulx A, Tremblay V, Brunzelle J, Couture JF.
    Structure; 2011 Jan 12; 19(1):101-8. PubMed ID: 21220120
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  • 18. The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein- Protein Interaction.
    Ye X, Chen G, Jin J, Zhang B, Wang Y, Cai Z, Ye F.
    Curr Med Chem; 2020 Jan 12; 27(33):5530-5542. PubMed ID: 31132972
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  • 19. MLL1/WDR5 complex in leukemogenesis and epigenetic regulation.
    Wu M, Shu HB.
    Chin J Cancer; 2011 Apr 12; 30(4):240-6. PubMed ID: 21439245
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  • 20. A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.
    Zhang P, Chaturvedi CP, Tremblay V, Cramet M, Brunzelle JS, Skiniotis G, Brand M, Shilatifard A, Couture JF.
    Genes Dev; 2015 Jan 15; 29(2):123-8. PubMed ID: 25593305
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