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180 related items for PubMed ID: 28192143

  • 1. Leucine-rich repeat containing 8A (LRRC8A)-dependent volume-regulated anion channel activity is dispensable for T-cell development and function.
    Platt CD, Chou J, Houlihan P, Badran YR, Kumar L, Bainter W, Poliani PL, Perez CJ, Dent SYR, Clapham DE, Benavides F, Geha RS.
    J Allergy Clin Immunol; 2017 Dec; 140(6):1651-1659.e1. PubMed ID: 28192143
    [Abstract] [Full Text] [Related]

  • 2. Leucine-rich repeat containing protein LRRC8A is essential for swelling-activated Cl- currents and embryonic development in zebrafish.
    Yamada T, Wondergem R, Morrison R, Yin VP, Strange K.
    Physiol Rep; 2016 Oct; 4(19):. PubMed ID: 27688432
    [Abstract] [Full Text] [Related]

  • 3. Intracellular and extracellular loops of LRRC8 are essential for volume-regulated anion channel function.
    Yamada T, Strange K.
    J Gen Physiol; 2018 Jul 02; 150(7):1003-1015. PubMed ID: 29853476
    [Abstract] [Full Text] [Related]

  • 4. LRRC8/VRAC anion channels are required for late stages of spermatid development in mice.
    Lück JC, Puchkov D, Ullrich F, Jentsch TJ.
    J Biol Chem; 2018 Jul 27; 293(30):11796-11808. PubMed ID: 29880644
    [Abstract] [Full Text] [Related]

  • 5. Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice.
    Bao J, Perez CJ, Kim J, Zhang H, Murphy CJ, Hamidi T, Jaubert J, Platt CD, Chou J, Deng M, Zhou MH, Huang Y, Gaitán-Peñas H, Guénet JL, Lin K, Lu Y, Chen T, Bedford MT, Dent SY, Richburg JH, Estévez R, Pan HL, Geha RS, Shi Q, Benavides F.
    JCI Insight; 2018 Aug 23; 3(16):. PubMed ID: 30135305
    [Abstract] [Full Text] [Related]

  • 6. LRRC8A contributes to angiotensin II-induced cardiac hypertrophy by interacting with NADPH oxidases via the C-terminal leucine-rich repeat domain.
    Huo C, Liu Y, Li X, Xu R, Jia X, Hou L, Wang X.
    Free Radic Biol Med; 2021 Mar 23; 165():191-202. PubMed ID: 33515753
    [Abstract] [Full Text] [Related]

  • 7. LRRC8A is essential for swelling-activated chloride current and for regulatory volume decrease in astrocytes.
    Formaggio F, Saracino E, Mola MG, Rao SB, Amiry-Moghaddam M, Muccini M, Zamboni R, Nicchia GP, Caprini M, Benfenati V.
    FASEB J; 2019 Jan 23; 33(1):101-113. PubMed ID: 29957062
    [Abstract] [Full Text] [Related]

  • 8. Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function.
    Kumar L, Chou J, Yee CS, Borzutzky A, Vollmann EH, von Andrian UH, Park SY, Hollander G, Manis JP, Poliani PL, Geha RS.
    J Exp Med; 2014 May 05; 211(5):929-42. PubMed ID: 24752297
    [Abstract] [Full Text] [Related]

  • 9. Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
    Voss FK, Ullrich F, Münch J, Lazarow K, Lutter D, Mah N, Andrade-Navarro MA, von Kries JP, Stauber T, Jentsch TJ.
    Science; 2014 May 09; 344(6184):634-8. PubMed ID: 24790029
    [Abstract] [Full Text] [Related]

  • 10. LRRC8A-dependent volume-regulated anion channels contribute to ischemia-induced brain injury and glutamatergic input to hippocampal neurons.
    Zhou JJ, Luo Y, Chen SR, Shao JY, Sah R, Pan HL.
    Exp Neurol; 2020 Oct 09; 332():113391. PubMed ID: 32598930
    [Abstract] [Full Text] [Related]

  • 11. TTYH1 and TTYH2 Serve as LRRC8A-Independent Volume-Regulated Anion Channels in Cancer Cells.
    Bae Y, Kim A, Cho CH, Kim D, Jung HG, Kim SS, Yoo J, Park JY, Hwang EM.
    Cells; 2019 Jun 09; 8(6):. PubMed ID: 31181821
    [Abstract] [Full Text] [Related]

  • 12. Absolute Protein Amounts and Relative Abundance of Volume-regulated Anion Channel (VRAC) LRRC8 Subunits in Cells and Tissues Revealed by Quantitative Immunoblotting.
    Pervaiz S, Kopp A, von Kleist L, Stauber T.
    Int J Mol Sci; 2019 Nov 23; 20(23):. PubMed ID: 31771171
    [Abstract] [Full Text] [Related]

  • 13. The identification of a volume-regulated anion channel: an amazing Odyssey.
    Pedersen SF, Klausen TK, Nilius B.
    Acta Physiol (Oxf); 2015 Apr 23; 213(4):868-81. PubMed ID: 25565132
    [Abstract] [Full Text] [Related]

  • 14. Molecular Biology and Physiology of Volume-Regulated Anion Channel (VRAC).
    Osei-Owusu J, Yang J, Vitery MDC, Qiu Z.
    Curr Top Membr; 2018 Apr 23; 81():177-203. PubMed ID: 30243432
    [Abstract] [Full Text] [Related]

  • 15. Chloride Channel-3 (ClC-3) Modifies the Trafficking of Leucine-Rich Repeat-Containing 8A (LRRC8A) Anion Channels.
    Stark RJ, Nguyen HN, Bacon MK, Rohrbough JC, Choi H, Lamb FS.
    J Membr Biol; 2023 Apr 23; 256(2):125-135. PubMed ID: 36322172
    [Abstract] [Full Text] [Related]

  • 16. LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis.
    Choi H, Ettinger N, Rohrbough J, Dikalova A, Nguyen HN, Lamb FS.
    Free Radic Biol Med; 2016 Dec 23; 101():413-423. PubMed ID: 27838438
    [Abstract] [Full Text] [Related]

  • 17. Downregulation of Leucine-Rich Repeat-Containing 8A Limits Proliferation and Increases Sensitivity of Glioblastoma to Temozolomide and Carmustine.
    Rubino S, Bach MD, Schober AL, Lambert IH, Mongin AA.
    Front Oncol; 2018 Dec 23; 8():142. PubMed ID: 29868469
    [Abstract] [Full Text] [Related]

  • 18. Biophysics and Physiology of the Volume-Regulated Anion Channel (VRAC)/Volume-Sensitive Outwardly Rectifying Anion Channel (VSOR).
    Pedersen SF, Okada Y, Nilius B.
    Pflugers Arch; 2016 Mar 23; 468(3):371-83. PubMed ID: 26739710
    [Abstract] [Full Text] [Related]

  • 19. The LRRC8/VRAC anion channel facilitates myogenic differentiation of murine myoblasts by promoting membrane hyperpolarization.
    Chen L, Becker TM, Koch U, Stauber T.
    J Biol Chem; 2019 Sep 27; 294(39):14279-14288. PubMed ID: 31387946
    [Abstract] [Full Text] [Related]

  • 20. Molecular composition and heterogeneity of the LRRC8-containing swelling-activated osmolyte channels in primary rat astrocytes.
    Schober AL, Wilson CS, Mongin AA.
    J Physiol; 2017 Nov 15; 595(22):6939-6951. PubMed ID: 28833202
    [Abstract] [Full Text] [Related]

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