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114 related items for PubMed ID: 28192710

  • 1. Rational design of reversible inhibitors for trehalose 6-phosphate phosphatases.
    Liu C, Dunaway-Mariano D, Mariano PS.
    Eur J Med Chem; 2017 Mar 10; 128():274-286. PubMed ID: 28192710
    [Abstract] [Full Text] [Related]

  • 2. Structural Analysis of Binding Determinants of Salmonella typhimurium Trehalose-6-phosphate Phosphatase Using Ground-State Complexes.
    Harvey CM, O'Toole KH, Liu C, Mariano P, Dunaway-Mariano D, Allen KN.
    Biochemistry; 2020 Sep 08; 59(35):3247-3257. PubMed ID: 32786412
    [Abstract] [Full Text] [Related]

  • 3. Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs.
    Farelli JD, Galvin BD, Li Z, Liu C, Aono M, Garland M, Hallett OE, Causey TB, Ali-Reynolds A, Saltzberg DJ, Carlow CK, Dunaway-Mariano D, Allen KN.
    PLoS Pathog; 2014 Jul 08; 10(7):e1004245. PubMed ID: 24992307
    [Abstract] [Full Text] [Related]

  • 4. Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.
    Korte J, Alber M, Trujillo CM, Syson K, Koliwer-Brandl H, Deenen R, Köhrer K, DeJesus MA, Hartman T, Jacobs WR, Bornemann S, Ioerger TR, Ehrt S, Kalscheuer R.
    PLoS Pathog; 2016 Dec 08; 12(12):e1006043. PubMed ID: 27936238
    [Abstract] [Full Text] [Related]

  • 5. Trehalose synthesis inhibitor: A molecular in silico drug design.
    Gonçalves LM, Trevisol ETV, de Azevedo Abrahim Vieira B, De Mesquita JF.
    J Cell Biochem; 2020 Feb 08; 121(2):1114-1125. PubMed ID: 31478225
    [Abstract] [Full Text] [Related]

  • 6. Cloning, expression, purification and kinetics of trehalose-6-phosphate phosphatase of filarial parasite Brugia malayi.
    Kushwaha S, Singh PK, Rana AK, Misra-Bhattacharya S.
    Acta Trop; 2011 Aug 08; 119(2-3):151-9. PubMed ID: 21658361
    [Abstract] [Full Text] [Related]

  • 7. Trehalose-6-Phosphate as a Potential Lead Candidate for the Development of Tps1 Inhibitors: Insights from the Trehalose Biosynthesis Pathway in Diverse Yeast Species.
    Magalhães RS, De Lima KC, de Almeida DS, De Mesquita JF, Eleutherio EC.
    Appl Biochem Biotechnol; 2017 Mar 08; 181(3):914-924. PubMed ID: 27796871
    [Abstract] [Full Text] [Related]

  • 8. Structural insight into dephosphorylation by trehalose 6-phosphate phosphatase (OtsB2) from Mycobacterium tuberculosis.
    Shan S, Min H, Liu T, Jiang D, Rao Z.
    FASEB J; 2016 Dec 08; 30(12):3989-3996. PubMed ID: 27572957
    [Abstract] [Full Text] [Related]

  • 9. Substrate-binding recognition and specificity of trehalose phosphorylase from Schizophyllum commune examined in steady-state kinetic studies with deoxy and deoxyfluoro substrate analogues and inhibitors.
    Eis C, Nidetzky B.
    Biochem J; 2002 Apr 15; 363(Pt 2):335-40. PubMed ID: 11931662
    [Abstract] [Full Text] [Related]

  • 10. Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
    Miao Y, Tenor JL, Toffaletti DL, Washington EJ, Liu J, Shadrick WR, Schumacher MA, Lee RE, Perfect JR, Brennan RG.
    Proc Natl Acad Sci U S A; 2016 Jun 28; 113(26):7148-53. PubMed ID: 27307435
    [Abstract] [Full Text] [Related]

  • 11. Evaluation of acceptor selectivity of Lactococcus lactis ssp. lactis trehalose 6-phosphate phosphorylase in the reverse phosphorolysis and synthesis of a new sugar phosphate.
    Taguchi Y, Saburi W, Imai R, Mori H.
    Biosci Biotechnol Biochem; 2017 Aug 28; 81(8):1512-1519. PubMed ID: 28537141
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and in Vitro Characterization of Trehalose-Based Inhibitors of Mycobacterial Trehalose 6-Phosphate Phosphatases.
    Kapil S, Petit C, Drago VN, Ronning DR, Sucheck SJ.
    Chembiochem; 2019 Jan 18; 20(2):260-269. PubMed ID: 30402996
    [Abstract] [Full Text] [Related]

  • 13. Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
    Miao Y, Tenor JL, Toffaletti DL, Maskarinec SA, Liu J, Lee RE, Perfect JR, Brennan RG.
    mBio; 2017 Jul 25; 8(4):. PubMed ID: 28743811
    [Abstract] [Full Text] [Related]

  • 14. The level of sugars and synthesis of trehalose in Ascaris suum tissues.
    Dmitryjuk M, Łopieńska-Biernat E, Farjan M.
    J Helminthol; 2009 Sep 25; 83(3):237-43. PubMed ID: 19138450
    [Abstract] [Full Text] [Related]

  • 15. Probing function and structure of trehalose-6-phosphate phosphatases from pathogenic organisms suggests distinct molecular groupings.
    Cross M, Lepage R, Rajan S, Biberacher S, Young ND, Kim BN, Coster MJ, Gasser RB, Kim JS, Hofmann A.
    FASEB J; 2017 Mar 25; 31(3):920-926. PubMed ID: 27864376
    [Abstract] [Full Text] [Related]

  • 16. Biochemical characterization and ligand-binding properties of trehalose-6-phosphate phosphatase from Mycobacterium tuberculosis.
    Shi L, Zhang H, Qiu Y, Wang Q, Wu X, Wang H, Zhang X, Lin D.
    Acta Biochim Biophys Sin (Shanghai); 2013 Oct 25; 45(10):837-44. PubMed ID: 23903290
    [Abstract] [Full Text] [Related]

  • 17. Analysis of the trehalose synthesis pathway of Physarum polycehalum.
    Morita R, Okano S, Furukawa A, Ishii K, Teramoto C, Minami Y.
    Biochem Biophys Res Commun; 2023 Nov 19; 682():299-307. PubMed ID: 37832387
    [Abstract] [Full Text] [Related]

  • 18. Crystal structure of trehalose-6-phosphate phosphatase-related protein: biochemical and biological implications.
    Rao KN, Kumaran D, Seetharaman J, Bonanno JB, Burley SK, Swaminathan S.
    Protein Sci; 2006 Jul 19; 15(7):1735-44. PubMed ID: 16815921
    [Abstract] [Full Text] [Related]

  • 19. Cleavage of trehalose-phosphate in Bacillus subtilis is catalysed by a phospho-alpha-(1-1)-glucosidase encoded by the treA gene.
    Helfert C, Gotsche S, Dahl MK.
    Mol Microbiol; 1995 Apr 19; 16(1):111-120. PubMed ID: 7651129
    [Abstract] [Full Text] [Related]

  • 20. Characterization and regulation of the trehalose synthesis pathway and its importance in the pathogenicity of Cryptococcus neoformans.
    Petzold EW, Himmelreich U, Mylonakis E, Rude T, Toffaletti D, Cox GM, Miller JL, Perfect JR.
    Infect Immun; 2006 Oct 19; 74(10):5877-87. PubMed ID: 16988267
    [Abstract] [Full Text] [Related]

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