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Journal Abstract Search

112 related items for PubMed ID: 28219045

  • 1. Modulating the selectivity of matriptase-2 inhibitors with unnatural amino acids.
    St-Georges C, Désilets A, Béliveau F, Ghinet M, Dion SP, Colombo É, Boudreault PL, Najmanovich RJ, Leduc R, Marsault É.
    Eur J Med Chem; 2017 Mar 31; 129():110-123. PubMed ID: 28219045
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  • 4. Use of protease substrate specificity screening in the rational design of selective protease inhibitors with unnatural amino acids: Application to HGFA, matriptase, and hepsin.
    Mahoney MW, Helander J, Kooner AS, Norman M, Damalanka VC, De Bona P, Kasperkiewicz P, Rut W, Poreba M, Kashipathy MM, Battaile KP, Lovell S, O'Donoghue AJ, Craik CS, Drag M, Janetka JW.
    Protein Sci; 2024 Aug 31; 33(8):e5110. PubMed ID: 39073183
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  • 7. Identification of the first low-molecular-weight inhibitors of matriptase-2.
    Sisay MT, Steinmetzer T, Stirnberg M, Maurer E, Hammami M, Bajorath J, Gütschow M.
    J Med Chem; 2010 Aug 12; 53(15):5523-35. PubMed ID: 20684597
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  • 10. Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets.
    Franco FM, Jones DE, Harris PK, Han Z, Wildman SA, Jarvis CM, Janetka JW.
    Bioorg Med Chem; 2015 May 15; 23(10):2328-43. PubMed ID: 25882520
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  • 11. Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis.
    Ramsay AJ, Hooper JD, Folgueras AR, Velasco G, López-Otín C.
    Haematologica; 2009 Jun 15; 94(6):840-9. PubMed ID: 19377077
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  • 12. Optimization of Ketobenzothiazole-Based Type II Transmembrane Serine Protease Inhibitors to Block H1N1 Influenza Virus Replication.
    Colombo É, Désilets A, Hassanzadeh M, Lemieux G, Marois I, Cliche D, Delbrouck JA, Murza A, Jean F, Marsault E, Richter MV, Leduc R, Boudreault PL.
    ChemMedChem; 2024 Jan 15; 19(2):e202300458. PubMed ID: 37864572
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  • 13. Design and chemical syntheses of potent matriptase-2 inhibitors based on trypsin inhibitor SFTI-1 isolated from sunflower seeds.
    Gitlin-Domagalska A, Dębowski D, Łęgowska A, Stirnberg M, Okońska J, Gütschow M, Rolka K.
    Biopolymers; 2017 Nov 15; 108(6):. PubMed ID: 28555756
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  • 14. Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6.
    Truksa J, Gelbart T, Peng H, Beutler E, Beutler B, Lee P.
    Br J Haematol; 2009 Nov 15; 147(4):571-81. PubMed ID: 19751239
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  • 15. Evaluation of bisbenzamidines as inhibitors for matriptase-2.
    Beckmann AM, Gilberg E, Gattner S, Huang TL, Vanden Eynde JJ, Mayence A, Bajorath J, Stirnberg M, Gütschow M.
    Bioorg Med Chem Lett; 2016 Aug 01; 26(15):3741-5. PubMed ID: 27287367
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  • 17. Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy.
    Goswami R, Mukherjee S, Ghadiyaram C, Wohlfahrt G, Sistla RK, Nagaraj J, Satyam LK, Subbarao K, Palakurthy RK, Gopinath S, Krishnamurthy NR, Ikonen T, Moilanen A, Subramanya HS, Kallio P, Ramachandra M.
    Bioorg Med Chem; 2014 Jun 15; 22(12):3187-203. PubMed ID: 24794746
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  • 18. Analysis of subpocket selectivity and identification of potent selective inhibitors for matriptase and matriptase-2.
    Duchêne D, Colombo E, Désilets A, Boudreault PL, Leduc R, Marsault E, Najmanovich R.
    J Med Chem; 2014 Dec 11; 57(23):10198-204. PubMed ID: 25387268
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