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164 related items for PubMed ID: 28221790

  • 1. Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.
    Tichý M, Smoleń S, Tloušt'ová E, Pohl R, Oždian T, Hejtmánková K, Lišková B, Gurská S, Džubák P, Hajdúch M, Hocek M.
    J Med Chem; 2017 Mar 23; 60(6):2411-2424. PubMed ID: 28221790
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.
    Tokarenko A, Lišková B, Smoleń S, Táborská N, Tichý M, Gurská S, Perlíková P, Frydrych I, Tloušt'ová E, Znojek P, Mertlíková-Kaiserová H, Poštová Slavětínská L, Pohl R, Klepetářová B, Khalid NU, Wenren Y, Laposa RR, Džubák P, Hajdúch M, Hocek M.
    J Med Chem; 2018 Oct 25; 61(20):9347-9359. PubMed ID: 30281308
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and Biological Profiling of Pyrazolo-Fused 7-Deazapurine Nucleosides.
    Fleuti M, Bártová K, Slavětínská LP, Tloušt'ová E, Tichý M, Gurská S, Pavliš P, Džubák P, Hajdúch M, Hocek M.
    J Org Chem; 2020 Aug 21; 85(16):10539-10551. PubMed ID: 32692916
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides.
    Veselovská L, Kudlová N, Gurská S, Lišková B, Medvedíková M, Hodek O, Tloušťová E, Milisavljevic N, Tichý M, Perlíková P, Mertlíková-Kaiserová H, Trylčová J, Pohl R, Klepetářová B, Džubák P, Hajdúch M, Hocek M.
    Chemistry; 2020 Oct 09; 26(57):13002-13015. PubMed ID: 32275109
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, Photophysical Properties, and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides.
    Yang C, Pohl R, Tichý M, Gurská S, Pavliš P, Džubák P, Hajdúch M, Hocek M.
    J Org Chem; 2020 Jun 19; 85(12):8085-8101. PubMed ID: 32432875
    [Abstract] [Full Text] [Related]

  • 6. Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides.
    Hocek M, Naus P, Pohl R, Votruba I, Furman PA, Tharnish PM, Otto MJ.
    J Med Chem; 2005 Sep 08; 48(18):5869-73. PubMed ID: 16134952
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, cytostatic, antimicrobial, and anti-HCV activity of 6-substituted 7-(het)aryl-7-deazapurine ribonucleosides.
    Nauš P, Caletková O, Konečný P, Džubák P, Bogdanová K, Kolář M, Vrbková J, Slavětínská L, Tloušt'ová E, Perlíková P, Hajdúch M, Hocek M.
    J Med Chem; 2014 Feb 13; 57(3):1097-110. PubMed ID: 24397620
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and antiviral evaluation of 2'-C-methyl analogues of 5-alkynyl- and 6-alkylfurano- and pyrrolo[2,3-d]pyrimidine ribonucleosides.
    Januszczyk P, Fogt J, Boryski J, Izawa K, Onishi T, Neyts J, De Clercq E.
    Nucleosides Nucleotides Nucleic Acids; 2009 May 13; 28(5):713-23. PubMed ID: 20183611
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4'-C-methylribonucleosides.
    Nauš P, Caletková O, Perlíková P, Poštová Slavětínská L, Tloušťová E, Hodek J, Weber J, Džubák P, Hajdúch M, Hocek M.
    Bioorg Med Chem; 2015 Dec 01; 23(23):7422-38. PubMed ID: 26558518
    [Abstract] [Full Text] [Related]

  • 10. Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: synthesis and evaluation of 6-substituted purine l-ribonucleosides.
    Hocek M, Silhár P, Shih IH, Mabery E, Mackman R.
    Bioorg Med Chem Lett; 2006 Oct 15; 16(20):5290-3. PubMed ID: 16905315
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and cytostatic and antiviral activities of 2'-deoxy-2',2'-difluororibo- and 2'-deoxy-2'-fluororibonucleosides derived from 7-(Het)aryl-7-deazaadenines.
    Perlíková P, Eberlin L, Ménová P, Raindlová V, Slavětínská L, Tloušťová E, Bahador G, Lee YJ, Hocek M.
    ChemMedChem; 2013 May 15; 8(5):832-46. PubMed ID: 23559483
    [Abstract] [Full Text] [Related]

  • 12. Synthesis of 7-trifluoromethyl-7-deazapurine ribonucleoside analogs and their monophosphate prodrugs.
    Cho JH, Bassit LC, Amblard F, Schinazi RF.
    Nucleosides Nucleotides Nucleic Acids; 2020 May 15; 39(5):671-687. PubMed ID: 31588837
    [Abstract] [Full Text] [Related]

  • 13. 6-(Het)aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents.
    Naus P, Pohl R, Votruba I, Dzubák P, Hajdúch M, Ameral R, Birkus G, Wang T, Ray AS, Mackman R, Cihlar T, Hocek M.
    J Med Chem; 2010 Jan 14; 53(1):460-70. PubMed ID: 19929004
    [Abstract] [Full Text] [Related]

  • 14. Pyrrolo[2,3-d]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides.
    Perlíková P, Hocek M.
    Med Res Rev; 2017 Nov 14; 37(6):1429-1460. PubMed ID: 28834581
    [Abstract] [Full Text] [Related]

  • 15. Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C-H Dibenzothiophenation and Negishi Coupling.
    Yang C, Slavětínská LP, Fleuti M, Klepetářová B, Tichý M, Gurská S, Pavliš P, Džubák P, Hajdúch M, Hocek M.
    J Am Chem Soc; 2022 Oct 26; 144(42):19437-19446. PubMed ID: 36245092
    [Abstract] [Full Text] [Related]

  • 16. Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of L-ascorbic or imino-L-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations.
    Stipković Babić M, Makuc D, Plavec J, Martinović T, Kraljević Pavelić S, Pavelić K, Snoeck R, Andrei G, Schols D, Wittine K, Mintas M.
    Eur J Med Chem; 2015 Sep 18; 102():288-302. PubMed ID: 26291038
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and antiproliferative and antiviral activity of carbohydrate-modified pyrrolo[2,3-d]pyridazin-7-one nucleosides.
    Meade EA, Wotring LL, Drach JC, Townsend LB.
    J Med Chem; 1997 Feb 28; 40(5):794-801. PubMed ID: 9057866
    [Abstract] [Full Text] [Related]

  • 18. Design and synthesis of novel carbocyclic versions of 2'-spirocyclopropyl ribonucleosides as potent anti-HCV agents.
    Oh CH, Kim E, Hong JH.
    Nucleosides Nucleotides Nucleic Acids; 2011 Jun 28; 30(6):423-39. PubMed ID: 21780908
    [Abstract] [Full Text] [Related]

  • 19. Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2'-C-methylribonucleosides, 2'-deoxy-2'-fluoroarabinonucleosides, arabinonucleosides and 2'-deoxyribonucleosides.
    Nauš P, Perlíková P, Bourderioux A, Pohl R, Slavětínská L, Votruba I, Bahador G, Birkuš G, Cihlář T, Hocek M.
    Bioorg Med Chem; 2012 Sep 01; 20(17):5202-14. PubMed ID: 22877872
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides.
    Tichý M, Pohl R, Tloušt'ová E, Weber J, Bahador G, Lee YJ, Hocek M.
    Bioorg Med Chem; 2013 Sep 01; 21(17):5362-72. PubMed ID: 23827234
    [Abstract] [Full Text] [Related]

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