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Journal Abstract Search

147 related items for PubMed ID: 28249757

  • 1. Suppression of spindly delays mitotic exit and exacerbates cell death response of cancer cells treated with low doses of paclitaxel.
    Silva PM, Ribeiro N, Lima RT, Andrade C, Diogo V, Teixeira J, Florindo C, Tavares Á, Vasconcelos MH, Bousbaa H.
    Cancer Lett; 2017 May 28; 394():33-42. PubMed ID: 28249757
    [Abstract] [Full Text] [Related]

  • 2. Antagonizing the spindle assembly checkpoint silencing enhances paclitaxel and Navitoclax-mediated apoptosis with distinct mechanistic.
    Henriques AC, Silva PMA, Sarmento B, Bousbaa H.
    Sci Rep; 2021 Feb 18; 11(1):4139. PubMed ID: 33603057
    [Abstract] [Full Text] [Related]

  • 3. Mitotic spindle disruption in human preimplantation embryos activates the spindle assembly checkpoint but not apoptosis until Day 5 of development.
    Jacobs K, Van de Velde H, De Paepe C, Sermon K, Spits C.
    Mol Hum Reprod; 2017 May 01; 23(5):321-329. PubMed ID: 28159965
    [Abstract] [Full Text] [Related]

  • 4. A Pyranoxanthone as a Potent Antimitotic and Sensitizer of Cancer Cells to Low Doses of Paclitaxel.
    França F, Silva PMA, Soares JX, Henriques AC, Loureiro DRP, Azevedo CMG, Afonso CMM, Bousbaa H.
    Molecules; 2020 Dec 10; 25(24):. PubMed ID: 33322077
    [Abstract] [Full Text] [Related]

  • 5. Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells.
    Choi M, Kim W, Cheon MG, Lee CW, Kim JE.
    Cancer Lett; 2015 Feb 28; 357(2):591-601. PubMed ID: 25524551
    [Abstract] [Full Text] [Related]

  • 6. JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis.
    He Z, Wu J, Su X, Zhang Y, Pan L, Wei H, Fang Q, Li H, Wang DL, Sun FL.
    J Biol Chem; 2016 Feb 26; 291(9):4684-97. PubMed ID: 26710852
    [Abstract] [Full Text] [Related]

  • 7. Imbalance of the spindle-assembly checkpoint promotes spindle poison-mediated cytotoxicity with distinct kinetics.
    Zeng X, Xu WK, Lok TM, Ma HT, Poon RYC.
    Cell Death Dis; 2019 Apr 05; 10(4):314. PubMed ID: 30952840
    [Abstract] [Full Text] [Related]

  • 8. The telomere/telomerase binding factor PinX1 regulates paclitaxel sensitivity depending on spindle assembly checkpoint in human cervical squamous cell carcinomas.
    Tian XP, Qian D, He LR, Huang H, Mai SJ, Li CP, Huang XX, Cai MY, Liao YJ, Kung HF, Zeng YX, Xie D.
    Cancer Lett; 2014 Oct 10; 353(1):104-14. PubMed ID: 25045845
    [Abstract] [Full Text] [Related]

  • 9. Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.
    Huang HC, Shi J, Orth JD, Mitchison TJ.
    Cancer Cell; 2009 Oct 06; 16(4):347-58. PubMed ID: 19800579
    [Abstract] [Full Text] [Related]

  • 10. CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells.
    Dinić J, Ríos-Luci C, Karpaviciene I, Cikotiene I, Fernandes MX, Pešić M, Padrón JM.
    Invest New Drugs; 2020 Jun 06; 38(3):584-598. PubMed ID: 31177401
    [Abstract] [Full Text] [Related]

  • 11. Post-slippage multinucleation renders cytotoxic variation in anti-mitotic drugs that target the microtubules or mitotic spindle.
    Zhu Y, Zhou Y, Shi J.
    Cell Cycle; 2014 Jun 06; 13(11):1756-64. PubMed ID: 24694730
    [Abstract] [Full Text] [Related]

  • 12. Length of mitotic arrest induced by microtubule-stabilizing drugs determines cell death after mitotic exit.
    Bekier ME, Fischbach R, Lee J, Taylor WR.
    Mol Cancer Ther; 2009 Jun 06; 8(6):1646-54. PubMed ID: 19509263
    [Abstract] [Full Text] [Related]

  • 13. BZML, a novel colchicine binding site inhibitor, overcomes multidrug resistance in A549/Taxol cells by inhibiting P-gp function and inducing mitotic catastrophe.
    Bai Z, Gao M, Zhang H, Guan Q, Xu J, Li Y, Qi H, Li Z, Zuo D, Zhang W, Wu Y.
    Cancer Lett; 2017 Aug 28; 402():81-92. PubMed ID: 28576750
    [Abstract] [Full Text] [Related]

  • 14. Microtubule dynamics, mitotic arrest, and apoptosis: drug-induced differential effects of betaIII-tubulin.
    Gan PP, McCarroll JA, Po'uha ST, Kamath K, Jordan MA, Kavallaris M.
    Mol Cancer Ther; 2010 May 28; 9(5):1339-48. PubMed ID: 20442307
    [Abstract] [Full Text] [Related]

  • 15. Boosting the apoptotic response of high-grade serous ovarian cancers with CCNE1 amplification to paclitaxel in vitro by targeting APC/C and the pro-survival protein MCL-1.
    Raab M, Kobayashi NF, Becker S, Kurunci-Csacsko E, Krämer A, Strebhardt K, Sanhaji M.
    Int J Cancer; 2020 Feb 15; 146(4):1086-1098. PubMed ID: 31286496
    [Abstract] [Full Text] [Related]

  • 16. HDAC2/3 binding and deacetylation of BubR1 initiates spindle assembly checkpoint silencing.
    Park I, Kwon MS, Paik S, Kim H, Lee HO, Choi E, Lee H.
    FEBS J; 2017 Dec 15; 284(23):4035-4050. PubMed ID: 28985013
    [Abstract] [Full Text] [Related]

  • 17. The Fcp1-Wee1-Cdk1 axis affects spindle assembly checkpoint robustness and sensitivity to antimicrotubule cancer drugs.
    Visconti R, Della Monica R, Palazzo L, D'Alessio F, Raia M, Improta S, Villa MR, Del Vecchio L, Grieco D.
    Cell Death Differ; 2015 Sep 15; 22(9):1551-60. PubMed ID: 25744022
    [Abstract] [Full Text] [Related]

  • 18. Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells – a critical role of Cdk1 in mitotic entry.
    Chang WL, Yu CC, Chen CS, Guh JH.
    Biochem Pharmacol; 2015 Mar 01; 94(1):12-21. PubMed ID: 25615907
    [Abstract] [Full Text] [Related]

  • 19. Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules.
    Di Cesare E, Verrico A, Miele A, Giubettini M, Rovella P, Coluccia A, Famiglini V, La Regina G, Cundari E, Silvestri R, Lavia P.
    Oncotarget; 2017 Mar 21; 8(12):19738-19759. PubMed ID: 28160569
    [Abstract] [Full Text] [Related]

  • 20. A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.
    Draviam VM, Stegmeier F, Nalepa G, Sowa ME, Chen J, Liang A, Hannon GJ, Sorger PK, Harper JW, Elledge SJ.
    Nat Cell Biol; 2007 May 21; 9(5):556-64. PubMed ID: 17417629
    [Abstract] [Full Text] [Related]

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