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1003 related items for PubMed ID: 28275161

  • 1. Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition.
    Liu CC, Hu J, Zhao N, Wang J, Wang N, Cirrito JR, Kanekiyo T, Holtzman DM, Bu G.
    J Neurosci; 2017 Apr 12; 37(15):4023-4031. PubMed ID: 28275161
    [Abstract] [Full Text] [Related]

  • 2. Neuronal clearance of amyloid-β by endocytic receptor LRP1.
    Kanekiyo T, Cirrito JR, Liu CC, Shinohara M, Li J, Schuler DR, Shinohara M, Holtzman DM, Bu G.
    J Neurosci; 2013 Dec 04; 33(49):19276-83. PubMed ID: 24305823
    [Abstract] [Full Text] [Related]

  • 3. A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Aβ Clearance.
    Zhang H, Chen W, Tan Z, Zhang L, Dong Z, Cui W, Zhao K, Wang H, Jing H, Cao R, Kim C, Safar JG, Xiong WC, Mei L.
    J Neurosci; 2020 Jul 08; 40(28):5347-5361. PubMed ID: 32457076
    [Abstract] [Full Text] [Related]

  • 4. LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.
    Kanekiyo T, Liu CC, Shinohara M, Li J, Bu G.
    J Neurosci; 2012 Nov 14; 32(46):16458-65. PubMed ID: 23152628
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
    Shackleton B, Crawford F, Bachmeier C.
    Fluids Barriers CNS; 2016 Aug 08; 13(1):14. PubMed ID: 27503326
    [Abstract] [Full Text] [Related]

  • 6. LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer's Disease.
    Van Gool B, Storck SE, Reekmans SM, Lechat B, Gordts PLSM, Pradier L, Pietrzik CU, Roebroek AJM.
    Mol Neurobiol; 2019 Oct 08; 56(10):7234-7245. PubMed ID: 31004319
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  • 10. Silencing of LRP1 Exacerbates Inflammatory Response Via TLR4/NF-κB/MAPKs Signaling Pathways in APP/PS1 Transgenic Mice.
    He Y, Ruganzu JB, Zheng Q, Wu X, Jin H, Peng X, Ding B, Lin C, Ji S, Ma Y, Yang W.
    Mol Neurobiol; 2020 Sep 08; 57(9):3727-3743. PubMed ID: 32572761
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  • 11. Functional role of lipoprotein receptors in Alzheimer's disease.
    Jaeger S, Pietrzik CU.
    Curr Alzheimer Res; 2008 Feb 08; 5(1):15-25. PubMed ID: 18288927
    [Abstract] [Full Text] [Related]

  • 12. LRP1 knockdown aggravates Aβ1-42-stimulated microglial and astrocytic neuroinflammatory responses by modulating TLR4/NF-κB/MAPKs signaling pathways.
    He Y, Ruganzu JB, Jin H, Peng X, Ji S, Ma Y, Zheng L, Yang W.
    Exp Cell Res; 2020 Sep 15; 394(2):112166. PubMed ID: 32645395
    [Abstract] [Full Text] [Related]

  • 13. Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier.
    Storck SE, Meister S, Nahrath J, Meißner JN, Schubert N, Di Spiezio A, Baches S, Vandenbroucke RE, Bouter Y, Prikulis I, Korth C, Weggen S, Heimann A, Schwaninger M, Bayer TA, Pietrzik CU.
    J Clin Invest; 2016 Jan 15; 126(1):123-36. PubMed ID: 26619118
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  • 14. Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis.
    Xiao Q, Yan P, Ma X, Liu H, Perez R, Zhu A, Gonzales E, Burchett JM, Schuler DR, Cirrito JR, Diwan A, Lee JM.
    J Neurosci; 2014 Jul 16; 34(29):9607-20. PubMed ID: 25031402
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  • 15. Mitogen-activated protein kinase signaling pathways promote low-density lipoprotein receptor-related protein 1-mediated internalization of beta-amyloid protein in primary cortical neurons.
    Yang WN, Ma KG, Qian YH, Zhang JS, Feng GF, Shi LL, Zhang ZC, Liu ZH.
    Int J Biochem Cell Biol; 2015 Jul 16; 64():252-64. PubMed ID: 25936756
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  • 16. The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM.
    Storck SE, Hartz AMS, Bernard J, Wolf A, Kachlmeier A, Mahringer A, Weggen S, Pahnke J, Pietrzik CU.
    Brain Behav Immun; 2018 Oct 16; 73():21-33. PubMed ID: 30041013
    [Abstract] [Full Text] [Related]

  • 17. Neuronal LRP1 regulates glucose metabolism and insulin signaling in the brain.
    Liu CC, Hu J, Tsai CW, Yue M, Melrose HL, Kanekiyo T, Bu G.
    J Neurosci; 2015 Apr 08; 35(14):5851-9. PubMed ID: 25855193
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  • 18. The p38 mitogen-activated protein kinase signaling pathway is involved in regulating low-density lipoprotein receptor-related protein 1-mediated β-amyloid protein internalization in mouse brain.
    Ma KG, Lv J, Hu XD, Shi LL, Chang KW, Chen XL, Qian YH, Yang WN, Qu QM.
    Int J Biochem Cell Biol; 2016 Jul 08; 76():75-86. PubMed ID: 27163530
    [Abstract] [Full Text] [Related]

  • 19. 1,25-Dihydroxyvitamin D3 regulates expression of LRP1 and RAGE in vitro and in vivo, enhancing Aβ1-40 brain-to-blood efflux and peripheral uptake transport.
    Guo YX, He LY, Zhang M, Wang F, Liu F, Peng WX.
    Neuroscience; 2016 May 13; 322():28-38. PubMed ID: 26820600
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  • 20. The role of LRP1 in Aβ efflux transport across the blood-brain barrier and cognitive dysfunction in diabetes mellitus.
    P X, Zz L, Gg J, Lp W, Cm B, Yl W, Chen MF, W L.
    Neurochem Int; 2022 Nov 13; 160():105417. PubMed ID: 36067928
    [Abstract] [Full Text] [Related]

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