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744 related items for PubMed ID: 28275719

  • 1. A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice.
    Zanos P, Nelson ME, Highland JN, Krimmel SR, Georgiou P, Gould TD, Thompson SM.
    eNeuro; 2017; 4(1):. PubMed ID: 28275719
    [Abstract] [Full Text] [Related]

  • 2. Rapid Antidepressant Action and Restoration of Excitatory Synaptic Strength After Chronic Stress by Negative Modulators of Alpha5-Containing GABAA Receptors.
    Fischell J, Van Dyke AM, Kvarta MD, LeGates TA, Thompson SM.
    Neuropsychopharmacology; 2015 Oct; 40(11):2499-509. PubMed ID: 25900119
    [Abstract] [Full Text] [Related]

  • 3. Comparison of rapid and long-lasting antidepressant effects of negative modulators of α5-containing GABAA receptors and (R)‑ketamine in a chronic social defeat stress model.
    Xiong Z, Zhang K, Ishima T, Ren Q, Chang L, Chen J, Hashimoto K.
    Pharmacol Biochem Behav; 2018 Dec; 175():139-145. PubMed ID: 30359627
    [Abstract] [Full Text] [Related]

  • 4. Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice.
    Troppoli TA, Zanos P, Georgiou P, Gould TD, Rudolph U, Thompson SM.
    Biol Psychiatry; 2022 Aug 01; 92(3):216-226. PubMed ID: 35120711
    [Abstract] [Full Text] [Related]

  • 5. Requirement of AMPA receptor stimulation for the sustained antidepressant activity of ketamine and LY341495 during the forced swim test in rats.
    Koike H, Chaki S.
    Behav Brain Res; 2014 Sep 01; 271():111-5. PubMed ID: 24909673
    [Abstract] [Full Text] [Related]

  • 6. Involvement of AMPA receptors in the antidepressant-like effects of dextromethorphan in mice.
    Nguyen L, Matsumoto RR.
    Behav Brain Res; 2015 Dec 15; 295():26-34. PubMed ID: 25804358
    [Abstract] [Full Text] [Related]

  • 7. Cortical and raphe GABAA, AMPA receptors and glial GLT-1 glutamate transporter contribute to the sustained antidepressant activity of ketamine.
    Pham TH, Defaix C, Nguyen TML, Mendez-David I, Tritschler L, David DJ, Gardier AM.
    Pharmacol Biochem Behav; 2020 May 15; 192():172913. PubMed ID: 32201299
    [Abstract] [Full Text] [Related]

  • 8. Basmisanil, an α5-GABAAR negative allosteric modulator, produces rapid and sustained antidepressant-like responses in male mice.
    Daher F, Villalobos NA, Hanley M, Atack JR, Popa MO, Fogaça MV.
    Neurosci Lett; 2024 Jun 11; 833():137828. PubMed ID: 38772437
    [Abstract] [Full Text] [Related]

  • 9. Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression.
    Koike H, Iijima M, Chaki S.
    Behav Brain Res; 2011 Oct 10; 224(1):107-11. PubMed ID: 21669235
    [Abstract] [Full Text] [Related]

  • 10. The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits.
    Witkin JM, Monn JA, Schoepp DD, Li X, Overshiner C, Mitchell SN, Carter G, Johnson B, Rasmussen K, Rorick-Kehn LM.
    J Pharmacol Exp Ther; 2016 Jul 10; 358(1):71-82. PubMed ID: 27189960
    [Abstract] [Full Text] [Related]

  • 11. NMDA Receptor Activation-Dependent Antidepressant-Relevant Behavioral and Synaptic Actions of Ketamine.
    Zanos P, Brown KA, Georgiou P, Yuan P, Zarate CA, Thompson SM, Gould TD.
    J Neurosci; 2023 Feb 08; 43(6):1038-1050. PubMed ID: 36596696
    [Abstract] [Full Text] [Related]

  • 12. NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice.
    Walker AK, Budac DP, Bisulco S, Lee AW, Smith RA, Beenders B, Kelley KW, Dantzer R.
    Neuropsychopharmacology; 2013 Aug 08; 38(9):1609-16. PubMed ID: 23511700
    [Abstract] [Full Text] [Related]

  • 13. Selective Pharmacological Augmentation of Hippocampal Activity Produces a Sustained Antidepressant-Like Response without Abuse-Related or Psychotomimetic Effects.
    Carreno FR, Collins GT, Frazer A, Lodge DJ.
    Int J Neuropsychopharmacol; 2017 Jun 01; 20(6):504-509. PubMed ID: 28339593
    [Abstract] [Full Text] [Related]

  • 14. Role of AMPA receptor stimulation and TrkB signaling in the antidepressant-like effect of ketamine co-administered with a group II mGlu receptor antagonist, LY341495, in the forced swim test in rats.
    Pałucha-Poniewiera A, Podkowa K, Pilc A.
    Behav Pharmacol; 2019 Sep 01; 30(6):471-477. PubMed ID: 30724804
    [Abstract] [Full Text] [Related]

  • 15. Changes in social, sexual, and hedonic behaviors in rats in response to stress and restoration by a negative allosteric modulator of α5-subunit containing GABA receptor.
    Bailey AM, Barrett A, Havens L, Leyder E, Merchant T, Starnes H, Thompson SM.
    Behav Brain Res; 2023 Aug 24; 452():114554. PubMed ID: 37356670
    [Abstract] [Full Text] [Related]

  • 16. R (-)-methoxetamine exerts rapid and sustained antidepressant effects and fewer behavioral side effects relative to S (+)-methoxetamine.
    Botanas CJ, Perez Custodio RJ, Kim HJ, de la Pena JB, Sayson LV, Ortiz DM, Kim M, Lee HJ, Acharya S, Kim KM, Lee CJ, Ryu JH, Lee YS, Cheong JH.
    Neuropharmacology; 2021 Aug 01; 193():108619. PubMed ID: 34023336
    [Abstract] [Full Text] [Related]

  • 17. Impact of subanesthetic doses of ketamine on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons.
    El Iskandrani KS, Oosterhof CA, El Mansari M, Blier P.
    J Psychopharmacol; 2015 Jul 01; 29(7):792-801. PubMed ID: 25759403
    [Abstract] [Full Text] [Related]

  • 18. Sex differences in the rapid and the sustained antidepressant-like effects of ketamine in stress-naïve and "depressed" mice exposed to chronic mild stress.
    Franceschelli A, Sens J, Herchick S, Thelen C, Pitychoutis PM.
    Neuroscience; 2015 Apr 02; 290():49-60. PubMed ID: 25595985
    [Abstract] [Full Text] [Related]

  • 19. Comparison of antidepressant and side effects in mice after intranasal administration of (R,S)-ketamine, (R)-ketamine, and (S)-ketamine.
    Chang L, Zhang K, Pu Y, Qu Y, Wang SM, Xiong Z, Ren Q, Dong C, Fujita Y, Hashimoto K.
    Pharmacol Biochem Behav; 2019 Jun 02; 181():53-59. PubMed ID: 31034852
    [Abstract] [Full Text] [Related]

  • 20. (2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray.
    Chou D, Peng HY, Lin TB, Lai CY, Hsieh MC, Wen YC, Lee AS, Wang HH, Yang PS, Chen GD, Ho YC.
    Neuropharmacology; 2018 Sep 01; 139():1-12. PubMed ID: 29953886
    [Abstract] [Full Text] [Related]

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