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PUBMED FOR HANDHELDS

Journal Abstract Search


278 related items for PubMed ID: 28342850

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  • 5. Crystal structure of the peroxisome proliferator-activated receptor gamma (PPARgamma) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design.
    Montanari R, Saccoccia F, Scotti E, Crestani M, Godio C, Gilardi F, Loiodice F, Fracchiolla G, Laghezza A, Tortorella P, Lavecchia A, Novellino E, Mazza F, Aschi M, Pochetti G.
    J Med Chem; 2008 Dec 25; 51(24):7768-76. PubMed ID: 19053776
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  • 6. Structural Basis for the Regulation of PPARγ Activity by Imatinib.
    Jang JY, Kim HJ, Han BW.
    Molecules; 2019 Oct 01; 24(19):. PubMed ID: 31581474
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  • 9. Development of an In Vitro Screening Platform for the Identification of Partial PPARγ Agonists as a Source for Antidiabetic Lead Compounds.
    Porskjær Christensen L, Bahij El-Houri R.
    Molecules; 2018 Sep 22; 23(10):. PubMed ID: 30248999
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  • 10. Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids.
    Waku T, Shiraki T, Oyama T, Fujimoto Y, Maebara K, Kamiya N, Jingami H, Morikawa K.
    J Mol Biol; 2009 Jan 09; 385(1):188-99. PubMed ID: 18977231
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  • 12. Peroxisome proliferator-activated receptor gamma (PPARγ) has multiple binding points that accommodate ligands in various conformations: Structurally similar PPARγ partial agonists bind to PPARγ LBD in different conformations.
    Ohashi M, Gamo K, Oyama T, Miyachi H.
    Bioorg Med Chem Lett; 2015 Jul 15; 25(14):2758-62. PubMed ID: 26025876
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  • 15. Different structures of the two peroxisome proliferator-activated receptor gamma (PPARγ) ligand-binding domains in homodimeric complex with partial agonist, but not full agonist.
    Ohashi M, Oyama T, Miyachi H.
    Bioorg Med Chem Lett; 2015 Jul 01; 25(13):2639-44. PubMed ID: 25987371
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  • 16. Peroxisome Proliferator-Activated Receptor γ (PPARγ) and Ligand Choreography: Newcomers Take the Stage.
    Garcia-Vallvé S, Guasch L, Tomas-Hernández S, del Bas JM, Ollendorff V, Arola L, Pujadas G, Mulero M.
    J Med Chem; 2015 Jul 23; 58(14):5381-94. PubMed ID: 25734377
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  • 19. Structural Basis for Anti-non-alcoholic Fatty Liver Disease and Diabetic Dyslipidemia Drug Saroglitazar as a PPAR α/γ Dual Agonist.
    Honda A, Kamata S, Satta C, Machida Y, Uchii K, Terasawa K, Nemoto A, Oyama T, Ishii I.
    Biol Pharm Bull; 2021 Jul 23; 44(9):1210-1219. PubMed ID: 34471049
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  • 20. Ligands for the Nuclear Peroxisome Proliferator-Activated Receptor Gamma.
    Sauer S.
    Trends Pharmacol Sci; 2015 Oct 23; 36(10):688-704. PubMed ID: 26435213
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