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Journal Abstract Search

191 related items for PubMed ID: 28371398

  • 1. Targeting Tankyrase to Fight WNT-dependent Tumours.
    Thorvaldsen TE.
    Basic Clin Pharmacol Toxicol; 2017 Aug; 121(2):81-88. PubMed ID: 28371398
    [Abstract] [Full Text] [Related]

  • 2. Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors.
    Ferri M, Liscio P, Carotti A, Asciutti S, Sardella R, Macchiarulo A, Camaioni E.
    Eur J Med Chem; 2017 Dec 15; 142():506-522. PubMed ID: 29107427
    [Abstract] [Full Text] [Related]

  • 3. Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes.
    Thorvaldsen TE, Pedersen NM, Wenzel EM, Schultz SW, Brech A, Liestøl K, Waaler J, Krauss S, Stenmark H.
    Mol Cancer Res; 2015 Nov 15; 13(11):1487-501. PubMed ID: 26124443
    [Abstract] [Full Text] [Related]

  • 4. Tankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin Puncta.
    Martino-Echarri E, Brocardo MG, Mills KM, Henderson BR.
    PLoS One; 2016 Nov 15; 11(3):e0150484. PubMed ID: 26930278
    [Abstract] [Full Text] [Related]

  • 5. Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding.
    Mariotti L, Pollock K, Guettler S.
    Br J Pharmacol; 2017 Dec 15; 174(24):4611-4636. PubMed ID: 28910490
    [Abstract] [Full Text] [Related]

  • 6. Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity.
    Pedersen NM, Thorvaldsen TE, Schultz SW, Wenzel EM, Stenmark H.
    PLoS One; 2016 Dec 15; 11(8):e0160507. PubMed ID: 27482906
    [Abstract] [Full Text] [Related]

  • 7. The Anti-Tumor Activity of Succinyl Macrolactin A Is Mediated through the β-Catenin Destruction Complex via the Suppression of Tankyrase and PI3K/Akt.
    Regmi SC, Park SY, Kim SJ, Banskota S, Shah S, Kim DH, Kim JA.
    PLoS One; 2015 Dec 15; 10(11):e0141753. PubMed ID: 26544726
    [Abstract] [Full Text] [Related]

  • 8. APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.
    Tanaka N, Mashima T, Mizutani A, Sato A, Aoyama A, Gong B, Yoshida H, Muramatsu Y, Nakata K, Matsuura M, Katayama R, Nagayama S, Fujita N, Sugimoto Y, Seimiya H.
    Mol Cancer Ther; 2017 Apr 15; 16(4):752-762. PubMed ID: 28179481
    [Abstract] [Full Text] [Related]

  • 9. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.
    Lau T, Chan E, Callow M, Waaler J, Boggs J, Blake RA, Magnuson S, Sambrone A, Schutten M, Firestein R, Machon O, Korinek V, Choo E, Diaz D, Merchant M, Polakis P, Holsworth DD, Krauss S, Costa M.
    Cancer Res; 2013 May 15; 73(10):3132-44. PubMed ID: 23539443
    [Abstract] [Full Text] [Related]

  • 10. Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation.
    Thorvaldsen TE, Pedersen NM, Wenzel EM, Stenmark H.
    PLoS One; 2017 May 15; 12(1):e0170508. PubMed ID: 28107521
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells.
    Bao R, Christova T, Song S, Angers S, Yan X, Attisano L.
    PLoS One; 2012 May 15; 7(11):e48670. PubMed ID: 23144924
    [Abstract] [Full Text] [Related]

  • 12. RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.
    Mizutani A, Yashiroda Y, Muramatsu Y, Yoshida H, Chikada T, Tsumura T, Okue M, Shirai F, Fukami T, Yoshida M, Seimiya H.
    Cancer Sci; 2018 Dec 15; 109(12):4003-4014. PubMed ID: 30238564
    [Abstract] [Full Text] [Related]

  • 13. Discovery of Novel Inhibitor for WNT/β-Catenin Pathway by Tankyrase 1/2 Structure-Based Virtual Screening.
    Li B, Liang J, Lu F, Zeng G, Zhang J, Ma Y, Liu P, Wang Q, Zhou Q, Chen L.
    Molecules; 2020 Apr 06; 25(7):. PubMed ID: 32268564
    [Abstract] [Full Text] [Related]

  • 14. Discovery of a Novel Triazolopyridine Derivative as a Tankyrase Inhibitor.
    Ryu H, Nam KY, Kim HJ, Song JY, Hwang SG, Kim JS, Kim J, Ahn J.
    Int J Mol Sci; 2021 Jul 08; 22(14):. PubMed ID: 34298950
    [Abstract] [Full Text] [Related]

  • 15. mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer.
    Mashima T, Taneda Y, Jang MK, Mizutani A, Muramatsu Y, Yoshida H, Sato A, Tanaka N, Sugimoto Y, Seimiya H.
    Oncotarget; 2017 Jul 18; 8(29):47902-47915. PubMed ID: 28615517
    [Abstract] [Full Text] [Related]

  • 16. Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells.
    Ma L, Wang X, Jia T, Wei W, Chua MS, So S.
    Oncotarget; 2015 Sep 22; 6(28):25390-401. PubMed ID: 26246473
    [Abstract] [Full Text] [Related]

  • 17. The Discovery and Characterization of K-756, a Novel Wnt/β-Catenin Pathway Inhibitor Targeting Tankyrase.
    Okada-Iwasaki R, Takahashi Y, Watanabe Y, Ishida H, Saito J, Nakai R, Asai A.
    Mol Cancer Ther; 2016 Jul 22; 15(7):1525-34. PubMed ID: 27196752
    [Abstract] [Full Text] [Related]

  • 18. A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.
    Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S.
    Cancer Res; 2012 Jun 01; 72(11):2822-32. PubMed ID: 22440753
    [Abstract] [Full Text] [Related]

  • 19. The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance.
    Quackenbush KS, Bagby S, Tai WM, Messersmith WA, Schreiber A, Greene J, Kim J, Wang G, Purkey A, Pitts TM, Nguyen A, Gao D, Blatchford P, Capasso A, Schuller AG, Eckhardt SG, Arcaroli JJ.
    Oncotarget; 2016 May 10; 7(19):28273-85. PubMed ID: 27070088
    [Abstract] [Full Text] [Related]

  • 20. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.
    Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F.
    Nature; 2009 Oct 01; 461(7264):614-20. PubMed ID: 19759537
    [Abstract] [Full Text] [Related]

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