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Journal Abstract Search

1180 related items for PubMed ID: 28388521

  • 1. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
    Lan JS, Zhang T, Liu Y, Yang J, Xie SS, Liu J, Miao ZY, Ding Y.
    Eur J Med Chem; 2017 Jun 16; 133():184-196. PubMed ID: 28388521
    [Abstract] [Full Text] [Related]

  • 2. Rational modification of donepezil as multifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    Wang ZM, Cai P, Liu QH, Xu DQ, Yang XL, Wu JJ, Kong LY, Wang XB.
    Eur J Med Chem; 2016 Nov 10; 123():282-297. PubMed ID: 27484514
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin.
    Wang J, Wang ZM, Li XM, Li F, Wu JJ, Kong LY, Wang XB.
    Bioorg Med Chem; 2016 Sep 15; 24(18):4324-4338. PubMed ID: 27460699
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, and evaluation of multitarget-directed ligands against Alzheimer's disease based on the fusion of donepezil and curcumin.
    Yan J, Hu J, Liu A, He L, Li X, Wei H.
    Bioorg Med Chem; 2017 Jun 15; 25(12):2946-2955. PubMed ID: 28454848
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS, Xie SS, Li SY, Pan LF, Wang XB, Kong LY.
    Bioorg Med Chem; 2014 Nov 01; 22(21):6089-104. PubMed ID: 25282654
    [Abstract] [Full Text] [Related]

  • 6. Donepezil-butylated hydroxytoluene (BHT) hybrids as Anti-Alzheimer's disease agents with cholinergic, antioxidant, and neuroprotective properties.
    Cai P, Fang SQ, Yang HL, Yang XL, Liu QH, Kong LY, Wang XB.
    Eur J Med Chem; 2018 Sep 05; 157():161-176. PubMed ID: 30096650
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and evaluation of novel cinnamic acid derivatives bearing N-benzyl pyridinium moiety as multifunctional cholinesterase inhibitors for Alzheimer's disease.
    Lan JS, Hou JW, Liu Y, Ding Y, Zhang Y, Li L, Zhang T.
    J Enzyme Inhib Med Chem; 2017 Dec 05; 32(1):776-788. PubMed ID: 28585866
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Jiang N, Huang Q, Liu J, Liang N, Li Q, Li Q, Xie SS.
    Eur J Med Chem; 2018 Feb 25; 146():287-298. PubMed ID: 29407958
    [Abstract] [Full Text] [Related]

  • 9. Biological evaluation of synthetic α,β-unsaturated carbonyl based cyclohexanone derivatives as neuroprotective novel inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
    Zha GF, Zhang CP, Qin HL, Jantan I, Sher M, Amjad MW, Hussain MA, Hussain Z, Bukhari SN.
    Bioorg Med Chem; 2016 May 15; 24(10):2352-9. PubMed ID: 27083471
    [Abstract] [Full Text] [Related]

  • 10. Novel salicylamide derivatives as potent multifunctional agents for the treatment of Alzheimer's disease: Design, synthesis and biological evaluation.
    Song Q, Li Y, Cao Z, Qiang X, Tan Z, Deng Y.
    Bioorg Chem; 2019 Mar 15; 84():137-149. PubMed ID: 30500523
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease.
    Lan JS, Ding Y, Liu Y, Kang P, Hou JW, Zhang XY, Xie SS, Zhang T.
    Eur J Med Chem; 2017 Oct 20; 139():48-59. PubMed ID: 28797883
    [Abstract] [Full Text] [Related]

  • 12. New benzyl pyridinium derivatives bearing 2,4-dioxochroman moiety as potent agents for treatment of Alzheimer's disease: Design, synthesis, biological evaluation, and docking study.
    Mollazadeh M, Mohammadi-Khanaposhtani M, Zonouzi A, Nadri H, Najafi Z, Larijani B, Mahdavi M.
    Bioorg Chem; 2019 Jun 20; 87():506-515. PubMed ID: 30928873
    [Abstract] [Full Text] [Related]

  • 13. Novel 3-benzylidene/benzylphthalide Mannich base derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
    Cao Z, Song Q, Yu G, Liu Z, Cong S, Tan Z, Deng Y.
    Bioorg Med Chem; 2021 Apr 01; 35():116074. PubMed ID: 33640707
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer's disease therapeutics.
    Kwon YE, Park JY, No KT, Shin JH, Lee SK, Eun JS, Yang JH, Shin TY, Kim DK, Chae BS, Leem JY, Kim KH.
    Bioorg Med Chem; 2007 Oct 15; 15(20):6596-607. PubMed ID: 17681794
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and evaluation of pterostilbene β-amino alcohol derivatives as multifunctional agents for Alzheimer's disease treatment.
    Zheng Y, Qiang X, Xu R, Song Q, Tian C, Liu H, Li W, Tan Z, Deng Y.
    Bioorg Chem; 2018 Aug 15; 78():298-306. PubMed ID: 29625269
    [Abstract] [Full Text] [Related]

  • 16. Novel chromanone-dithiocarbamate hybrids as multifunctional AChE inhibitors with β-amyloid anti-aggregation properties for the treatment of Alzheimer's disease.
    Jiang N, Ding J, Liu J, Sun X, Zhang Z, Mo Z, Li X, Yin H, Tang W, Xie SS.
    Bioorg Chem; 2019 Aug 15; 89():103027. PubMed ID: 31176237
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis, in-silico and biological evaluation of novel chalcone-O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z, Wang K, Shi J, Liu W, Tan Z.
    Eur J Med Chem; 2019 Sep 15; 178():726-739. PubMed ID: 31229875
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and biological evaluation of edaravone derivatives bearing the N-benzyl pyridinium moiety as multifunctional anti-Alzheimer's agents.
    Zondagh LS, Malan SF, Joubert J.
    J Enzyme Inhib Med Chem; 2020 Dec 15; 35(1):1596-1605. PubMed ID: 32779503
    [Abstract] [Full Text] [Related]

  • 19. Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates.
    Piemontese L, Tomás D, Hiremathad A, Capriati V, Candeias E, Cardoso SM, Chaves S, Santos MA.
    J Enzyme Inhib Med Chem; 2018 Dec 15; 33(1):1212-1224. PubMed ID: 30160188
    [Abstract] [Full Text] [Related]

  • 20. Rational Design and Multibiological Profiling of Novel Donepezil-Trolox Hybrids against Alzheimer's Disease, with Cholinergic, Antioxidant, Neuroprotective, and Cognition Enhancing Properties.
    Cai P, Fang SQ, Yang XL, Wu JJ, Liu QH, Hong H, Wang XB, Kong LY.
    ACS Chem Neurosci; 2017 Nov 15; 8(11):2496-2511. PubMed ID: 28806057
    [Abstract] [Full Text] [Related]

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