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Journal Abstract Search

1180 related items for PubMed ID: 28388521

  • 21. Design, synthesis, biological evaluation, and docking study of novel dual-acting thiazole-pyridiniums inhibiting acetylcholinesterase and β-amyloid aggregation for Alzheimer's disease.
    Ghotbi G, Mahdavi M, Najafi Z, Moghadam FH, Hamzeh-Mivehroud M, Davaran S, Dastmalchi S.
    Bioorg Chem; 2020 Oct; 103():104186. PubMed ID: 32890993
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  • 22. Design, synthesis and evaluation of chalcone Mannich base derivatives as multifunctional agents for the potential treatment of Alzheimer's disease.
    Zhang X, Song Q, Cao Z, Li Y, Tian C, Yang Z, Zhang H, Deng Y.
    Bioorg Chem; 2019 Jun; 87():395-408. PubMed ID: 30921741
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  • 23. Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
    Li F, Wang ZM, Wu JJ, Wang J, Xie SS, Lan JS, Xu W, Kong LY, Wang XB.
    J Enzyme Inhib Med Chem; 2016 Jun; 31(sup3):41-53. PubMed ID: 27384289
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  • 24. Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
    Riazimontazer E, Sadeghpour H, Nadri H, Sakhteman A, Tüylü Küçükkılınç T, Miri R, Edraki N.
    Bioorg Chem; 2019 Aug; 89():103006. PubMed ID: 31158577
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  • 25. Synthesis, biological evaluation and molecular modeling of benzofuran piperidine derivatives as Aβ antiaggregant.
    Chowdhury SR, Gu J, Hu Y, Wang J, Lei S, Tavallaie MS, Lam C, Lu D, Jiang F, Fu L.
    Eur J Med Chem; 2021 Oct 15; 222():113541. PubMed ID: 34116326
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  • 26. Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and β-amyloid aggregation inhibitors with neuroprotective properties.
    Guzior N, Bajda M, Skrok M, Kurpiewska K, Lewiński K, Brus B, Pišlar A, Kos J, Gobec S, Malawska B.
    Eur J Med Chem; 2015 Mar 06; 92():738-49. PubMed ID: 25621991
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  • 27. Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
    Dias Viegas FP, de Freitas Silva M, Divino da Rocha M, Castelli MR, Riquiel MM, Machado RP, Vaz SM, Simões de Lima LM, Mancini KC, Marques de Oliveira PC, Morais ÉP, Gontijo VS, da Silva FMR, D'Alincourt da Fonseca Peçanha D, Castro NG, Neves GA, Giusti-Paiva A, Vilela FC, Orlandi L, Camps I, Veloso MP, Leomil Coelho LF, Ionta M, Ferreira-Silva GÁ, Pereira RM, Dardenne LE, Guedes IA, de Oliveira Carneiro Junior W, Quaglio Bellozi PM, Pinheiro de Oliveira AC, Ferreira FF, Pruccoli L, Tarozzi A, Viegas C.
    Eur J Med Chem; 2018 Mar 10; 147():48-65. PubMed ID: 29421570
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  • 28. Design, synthesis, and in vitro evaluation of 4-aminoalkyl-1(2H)-phthalazinones as potential multifunctional anti-Alzheimer's disease agents.
    Ye C, Xu R, Cao Z, Song Q, Yu G, Shi Y, Liu Z, Liu X, Deng Y.
    Bioorg Chem; 2021 Jun 10; 111():104895. PubMed ID: 33887586
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  • 29. Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z, Qiang X, Li Y, Yuan W, Liu Q, Shi Y, Ang W, Luo Y, Tan Z, Deng Y.
    Eur J Med Chem; 2015 Apr 13; 94():348-66. PubMed ID: 25778991
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  • 30. Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents.
    Maqbool M, Manral A, Jameel E, Kumar J, Saini V, Shandilya A, Tiwari M, Hoda N, Jayaram B.
    Bioorg Med Chem; 2016 Jun 15; 24(12):2777-88. PubMed ID: 27157006
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  • 31. Design, synthesis, and evaluation of novel cinnamic acid-tryptamine hybrid for inhibition of acetylcholinesterase and butyrylcholinesterase.
    Ghafary S, Ghobadian R, Mahdavi M, Nadri H, Moradi A, Akbarzadeh T, Najafi Z, Sharifzadeh M, Edraki N, Moghadam FH, Amini M.
    Daru; 2020 Dec 15; 28(2):463-477. PubMed ID: 32372339
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  • 32. New phosphazine and phosphazide derivatives as multifunctional ligands targeting acetylcholinesterase and β-Amyloid aggregation for treatment of Alzheimer's disease.
    El-Sayed NF, El-Hussieny M, Ewies EF, Fouad MA, Boulos LS.
    Bioorg Chem; 2020 Jan 15; 95():103499. PubMed ID: 31838287
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  • 33. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Bolea I, Juárez-Jiménez J, de Los Ríos C, Chioua M, Pouplana R, Luque FJ, Unzeta M, Marco-Contelles J, Samadi A.
    J Med Chem; 2011 Dec 22; 54(24):8251-70. PubMed ID: 22023459
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  • 34. Synthesis and biological evaluation of new N-benzylpyridinium-based benzoheterocycles as potential anti-Alzheimer's agents.
    Salehi N, Mirjalili BBF, Nadri H, Abdolahi Z, Forootanfar H, Samzadeh-Kermani A, Küçükkılınç TT, Ayazgok B, Emami S, Haririan I, Sharifzadeh M, Foroumadi A, Khoobi M.
    Bioorg Chem; 2019 Mar 22; 83():559-568. PubMed ID: 30471578
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  • 35. Discovery of indanone derivatives as multi-target-directed ligands against Alzheimer's disease.
    Huang L, Miao H, Sun Y, Meng F, Li X.
    Eur J Med Chem; 2014 Nov 24; 87():429-39. PubMed ID: 25282266
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  • 36. Novel deoxyvasicinone derivatives as potent multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
    Ma F, Du H.
    Eur J Med Chem; 2017 Nov 10; 140():118-127. PubMed ID: 28923380
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  • 37. New racemic annulated pyrazolo[1,2-b]phthalazines as tacrine-like AChE inhibitors with potential use in Alzheimer's disease.
    Jalili-Baleh L, Nadri H, Moradi A, Bukhari SNA, Shakibaie M, Jafari M, Golshani M, Homayouni Moghadam F, Firoozpour L, Asadipour A, Emami S, Khoobi M, Foroumadi A.
    Eur J Med Chem; 2017 Oct 20; 139():280-289. PubMed ID: 28803044
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  • 38. Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a "Bio-Oxidizable" Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation.
    Peauger L, Azzouz R, Gembus V, Ţînţaş ML, Sopková-de Oliveira Santos J, Bohn P, Papamicaël C, Levacher V.
    J Med Chem; 2017 Jul 13; 60(13):5909-5926. PubMed ID: 28613859
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  • 39. Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo.
    Więckowska A, Więckowski K, Bajda M, Brus B, Sałat K, Czerwińska P, Gobec S, Filipek B, Malawska B.
    Bioorg Med Chem; 2015 May 15; 23(10):2445-57. PubMed ID: 25868744
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  • 40. Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives.
    Chakravarty H, Ju Y, Chen WH, Tam KY.
    Drug Dev Res; 2020 Apr 15; 81(2):242-255. PubMed ID: 31837041
    [Abstract] [Full Text] [Related]

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