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279 related items for PubMed ID: 28389584

  • 1. Control of Kir channel gating by cytoplasmic domain interface interactions.
    Borschel WF, Wang S, Lee S, Nichols CG.
    J Gen Physiol; 2017 May 01; 149(5):561-576. PubMed ID: 28389584
    [Abstract] [Full Text] [Related]

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    [No Abstract] [Full Text] [Related]

  • 3. N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2.
    Pratt EB, Tewson P, Bruederle CE, Skach WR, Shyng SL.
    J Gen Physiol; 2011 Mar 01; 137(3):299-314. PubMed ID: 21321069
    [Abstract] [Full Text] [Related]

  • 4. Conformational changes at cytoplasmic intersubunit interactions control Kir channel gating.
    Wang S, Borschel WF, Heyman S, Hsu P, Nichols CG.
    J Biol Chem; 2017 Jun 16; 292(24):10087-10096. PubMed ID: 28446610
    [Abstract] [Full Text] [Related]

  • 5. Destabilization of ATP-sensitive potassium channel activity by novel KCNJ11 mutations identified in congenital hyperinsulinism.
    Lin YW, Bushman JD, Yan FF, Haidar S, MacMullen C, Ganguly A, Stanley CA, Shyng SL.
    J Biol Chem; 2008 Apr 04; 283(14):9146-56. PubMed ID: 18250167
    [Abstract] [Full Text] [Related]

  • 6. ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP2 sensitivity.
    Pratt EB, Shyng SL.
    Channels (Austin); 2011 Apr 04; 5(4):314-9. PubMed ID: 21654216
    [Abstract] [Full Text] [Related]

  • 7. Stabilization of the activity of ATP-sensitive potassium channels by ion pairs formed between adjacent Kir6.2 subunits.
    Lin YW, Jia T, Weinsoft AM, Shyng SL.
    J Gen Physiol; 2003 Aug 04; 122(2):225-37. PubMed ID: 12885877
    [Abstract] [Full Text] [Related]

  • 8. Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.
    Driggers CM, Kuo YY, Zhu P, ElSheikh A, Shyng SL.
    Nat Commun; 2024 Mar 20; 15(1):2502. PubMed ID: 38509107
    [Abstract] [Full Text] [Related]

  • 9. Differential nucleotide regulation of KATP channels by SUR1 and SUR2A.
    Masia R, Enkvetchakul D, Nichols CG.
    J Mol Cell Cardiol; 2005 Sep 20; 39(3):491-501. PubMed ID: 15893323
    [Abstract] [Full Text] [Related]

  • 10. Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2).
    Ha J, Xu Y, Kawano T, Hendon T, Baki L, Garai S, Papapetropoulos A, Thakur GA, Plant LD, Logothetis DE.
    J Biol Chem; 2018 Mar 09; 293(10):3546-3561. PubMed ID: 29317494
    [Abstract] [Full Text] [Related]

  • 11. ATP-sensitive K+ channels: regulation of bursting by the sulphonylurea receptor, PIP2 and regions of Kir6.2.
    Ribalet B, John SA, Xie LH, Weiss JN.
    J Physiol; 2006 Mar 01; 571(Pt 2):303-17. PubMed ID: 16373383
    [Abstract] [Full Text] [Related]

  • 12. Characterization and functional restoration of a potassium channel Kir6.2 pore mutation identified in congenital hyperinsulinism.
    Bushman JD, Gay JW, Tewson P, Stanley CA, Shyng SL.
    J Biol Chem; 2010 Feb 26; 285(9):6012-23. PubMed ID: 20032456
    [Abstract] [Full Text] [Related]

  • 13. Sulfonylurea and K(+)-channel opener sensitivity of K(ATP) channels. Functional coupling of Kir6.2 and SUR1 subunits.
    Koster JC, Sha Q, Nichols CG.
    J Gen Physiol; 1999 Aug 26; 114(2):203-13. PubMed ID: 10435998
    [Abstract] [Full Text] [Related]

  • 14. Kir6.2 mutations associated with neonatal diabetes reduce expression of ATP-sensitive K+ channels: implications in disease mechanism and sulfonylurea therapy.
    Lin CW, Lin YW, Yan FF, Casey J, Kochhar M, Pratt EB, Shyng SL.
    Diabetes; 2006 Jun 26; 55(6):1738-46. PubMed ID: 16731837
    [Abstract] [Full Text] [Related]

  • 15. A Conserved Residue Cluster That Governs Kinetics of ATP-dependent Gating of Kir6.2 Potassium Channels.
    Zhang RS, Wright JD, Pless SA, Nunez JJ, Kim RY, Li JBW, Yang R, Ahern CA, Kurata HT.
    J Biol Chem; 2015 Jun 19; 290(25):15450-15461. PubMed ID: 25934393
    [Abstract] [Full Text] [Related]

  • 16. Remodelling of the SUR-Kir6.2 interface of the KATP channel upon ATP binding revealed by the conformational blocker rhodamine 123.
    Hosy E, Dérand R, Revilloud J, Vivaudou M.
    J Physiol; 2007 Jul 01; 582(Pt 1):27-39. PubMed ID: 17510180
    [Abstract] [Full Text] [Related]

  • 17. Sulfonylurea receptors regulate the channel pore in ATP-sensitive potassium channels via an intersubunit salt bridge.
    Lodwick D, Rainbow RD, Rubaiy HN, Al Johi M, Vuister GW, Norman RI.
    Biochem J; 2014 Dec 15; 464(3):343-54. PubMed ID: 25236767
    [Abstract] [Full Text] [Related]

  • 18. A novel KCNJ11 mutation associated with congenital hyperinsulinism reduces the intrinsic open probability of beta-cell ATP-sensitive potassium channels.
    Lin YW, MacMullen C, Ganguly A, Stanley CA, Shyng SL.
    J Biol Chem; 2006 Feb 03; 281(5):3006-12. PubMed ID: 16332676
    [Abstract] [Full Text] [Related]

  • 19. Regulation of KATP channel expression and activity by the SUR1 nucleotide binding fold 1.
    Masia R, Caputa G, Nichols CG.
    Channels (Austin); 2007 Feb 03; 1(4):315-23. PubMed ID: 18708750
    [Abstract] [Full Text] [Related]

  • 20. Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels.
    Zangerl-Plessl EM, Lee SJ, Maksaev G, Bernsteiner H, Ren F, Yuan P, Stary-Weinzinger A, Nichols CG.
    J Gen Physiol; 2020 Jan 06; 152(1):. PubMed ID: 31744859
    [Abstract] [Full Text] [Related]

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