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Journal Abstract Search

231 related items for PubMed ID: 28393419

  • 1. Synthesis and Evaluation of Novel [1,2,4]Triazolo[5,1-c][1,2,4]-triazines and Pyrazolo[5,1-c][1,2,4]triazines as Potential Antidiabetic Agents.
    Rusinov VL, Sapozhnikova IM, Bliznik AM, Chupakhin ON, Charushin VN, Spasov AA, Vassiliev PM, Kuznetsova VA, Rashchenko AI, Babkov DA.
    Arch Pharm (Weinheim); 2017 May; 350(5):. PubMed ID: 28393419
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors.
    Patel BD, Bhadada SV, Ghate MD.
    Bioorg Chem; 2017 Jun; 72():345-358. PubMed ID: 28302310
    [Abstract] [Full Text] [Related]

  • 3. Nitrothiadiazolo[3,2-a]pyrimidines as promising antiglycating agents.
    Savateev K, Fedotov V, Butorin I, Eltsov O, Slepukhin P, Ulomsky E, Rusinov V, Litvinov R, Babkov D, Khokhlacheva E, Radaev P, Vassiliev P, Spasov A.
    Eur J Med Chem; 2020 Jan 01; 185():111808. PubMed ID: 31683103
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and SAR of azolopyrimidines as potent and selective dipeptidyl peptidase-4 (DPP4) inhibitors for type 2 diabetes.
    Brigance RP, Meng W, Fura A, Harrity T, Wang A, Zahler R, Kirby MS, Hamann LG.
    Bioorg Med Chem Lett; 2010 Aug 01; 20(15):4395-8. PubMed ID: 20598534
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and biological evaluation of hetero-aromatic moieties substituted pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors.
    Ji X, Su M, Wang J, Deng G, Deng S, Li Z, Tang C, Li J, Li J, Zhao L, Jiang H, Liu H.
    Eur J Med Chem; 2014 Mar 21; 75():111-22. PubMed ID: 24531224
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors.
    Li N, Wang LJ, Jiang B, Guo SJ, Li XQ, Chen XC, Luo J, Li C, Wang Y, Shi DY.
    Bioorg Med Chem Lett; 2018 Jul 01; 28(12):2131-2135. PubMed ID: 29773502
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and discovery of triazolo-pyridazine-6-yl-substituted piperazines as effective anti-diabetic drugs; evaluated over dipeptidyl peptidase-4 inhibition mechanism and insulinotropic activities.
    Bindu B, Vijayalakshmi S, Manikandan A.
    Eur J Med Chem; 2020 Feb 01; 187():111912. PubMed ID: 31812034
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, structure-activity relationships, and docking studies of 1-(γ-1,2,3-triazol substituted prolyl)-(S)-3,3-difluoropyrrolidines as a novel series of potent and selective dipeptidyl peptidase-4 inhibitors.
    Zhang L, Su M, Li J, Ji X, Wang J, Li Z, Li J, Liu H.
    Chem Biol Drug Des; 2013 Feb 01; 81(2):198-207. PubMed ID: 22994702
    [Abstract] [Full Text] [Related]

  • 9. 6-Nitroazolo[1,5-a]pyrimidin-7(4H)-ones as Antidiabetic Agents.
    Spasov AA, Babkov DA, Sysoeva VA, Litvinov RA, Shamshina DD, Ulomsky EN, Savateev KV, Fedotov VV, Slepukhin PA, Chupakhin ON, Charushin VN, Rusinov VL.
    Arch Pharm (Weinheim); 2017 Dec 01; 350(12):. PubMed ID: 29152780
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of azobicyclo[3.3.0] octane derivatives as dipeptidyl peptidase 4 inhibitors for the treatment of type 2 diabetes.
    Cho TP, Long YF, Gang LZ, Yang W, Jun LH, Yuan SG, Hong FJ, Lin W, Liang GD, Lei Z, Jing LJ, Shen GA, Hong SG, Dan W, Ying F, Ke YP, Ying L, Jun F, Tai MX.
    Bioorg Med Chem Lett; 2010 Jun 15; 20(12):3565-8. PubMed ID: 20488702
    [Abstract] [Full Text] [Related]

  • 11. Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
    Li N, Wang LJ, Jiang B, Li XQ, Guo CL, Guo SJ, Shi DY.
    Eur J Med Chem; 2018 May 10; 151():145-157. PubMed ID: 29609120
    [Abstract] [Full Text] [Related]

  • 12. Integrated Protocol to Design Potential Inhibitors of Dipeptidyl Peptidase- 4 (DPP-4).
    Pantaleão SQ, Philot EA, de Oliveira Almeida M, Lima AN, de Sairre MI, Scott AL, Honorio KM.
    Curr Top Med Chem; 2020 May 10; 20(3):209-226. PubMed ID: 31878857
    [Abstract] [Full Text] [Related]

  • 13. Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling.
    Rea D, Van Elzen R, De Winter H, Van Goethem S, Landuyt B, Luyten W, Schoofs L, Van Der Veken P, Augustyns K, De Meester I, Fülöp V, Lambeir AM.
    Eur J Med Chem; 2017 Oct 20; 139():482-491. PubMed ID: 28826083
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, Structural Characterization and Docking Studies of Sulfamoyl- Phenyl Acid Esters as Dipeptidyl Peptidase-IV Inhibitors.
    Khalaf RA, Sabbah D, Al-Shalabi E, Al-Sheikh I, Albadawi G, Abu Sheikha G.
    Curr Comput Aided Drug Des; 2018 Oct 20; 14(2):142-151. PubMed ID: 29521244
    [Abstract] [Full Text] [Related]

  • 15. Pyrano[2,3-c]pyrazole fused spirooxindole-linked 1,2,3-triazoles as antioxidant agents: Exploring their utility in the development of antidiabetic drugs via inhibition of α-amylase and DPP4 activity.
    Chahal S, Rani P, Shweta, Goel KK, Joshi G, Singh R, Kumar P, Singh D, Sindhu J.
    Bioorg Chem; 2024 Jun 20; 147():107363. PubMed ID: 38657527
    [Abstract] [Full Text] [Related]

  • 16. Rapid generation of novel benzoic acid-based xanthine derivatives as highly potent, selective and long acting DPP-4 inhibitors: Scaffold-hopping and prodrug study.
    Li Q, Meng L, Zhou S, Deng X, Wang N, Ji Y, Peng Y, Xing J, Yao G.
    Eur J Med Chem; 2019 Oct 15; 180():509-523. PubMed ID: 31336309
    [Abstract] [Full Text] [Related]

  • 17. Identification of dipeptidyl peptidase IV inhibitors: virtual screening, synthesis and biological evaluation.
    Xing J, Li Q, Zhang S, Liu H, Zhao L, Cheng H, Zhang Y, Zhou J, Zhang H.
    Chem Biol Drug Des; 2014 Sep 15; 84(3):364-77. PubMed ID: 24674599
    [Abstract] [Full Text] [Related]

  • 18. Inhibitory evaluation of Curculigo latifolia on α-glucosidase, DPP (IV) and in vitro studies in antidiabetic with molecular docking relevance to type 2 diabetes mellitus.
    Zabidi NA, Ishak NA, Hamid M, Ashari SE, Mohammad Latif MA.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):109-121. PubMed ID: 33249946
    [Abstract] [Full Text] [Related]

  • 19. Dipeptidyl peptidase-4 inhibitor with β-amino amide scaffold: synthesis, SAR and biological evaluation.
    Kim HJ, Kwak WY, Min JP, Sung SY, Kim HD, Kim MK, Kim HS, Park KJ, Son MH, Kim SH, Lee BJ.
    Bioorg Med Chem Lett; 2012 Sep 01; 22(17):5545-9. PubMed ID: 22850208
    [Abstract] [Full Text] [Related]

  • 20. Discovery of Novel DPP-IV Inhibitors as Potential Candidates for the Treatment of Type 2 Diabetes mellitus Predicted by 3D QSAR Pharmacophore Models, Molecular Docking and de novo Evolution.
    Musoev A, Numonov S, You Z, Gao H.
    Molecules; 2019 Aug 07; 24(16):. PubMed ID: 31394858
    [Abstract] [Full Text] [Related]

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