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Journal Abstract Search

245 related items for PubMed ID: 28395199

  • 1. Design, synthesis, and biological evaluation of NAD(P)H: Quinone oxidoreductase (NQO1)-targeted oridonin prodrugs possessing indolequinone moiety for hypoxia-selective activation.
    Xu S, Yao H, Pei L, Hu M, Li D, Qiu Y, Wang G, Wu L, Yao H, Zhu Z, Xu J.
    Eur J Med Chem; 2017 May 26; 132():310-321. PubMed ID: 28395199
    [Abstract] [Full Text] [Related]

  • 2. Development of indolequinone mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1): NQO1 inhibition and growth inhibitory activity in human pancreatic MIA PaCa-2 cancer cells.
    Reigan P, Colucci MA, Siegel D, Chilloux A, Moody CJ, Ross D.
    Biochemistry; 2007 May 22; 46(20):5941-50. PubMed ID: 17455910
    [Abstract] [Full Text] [Related]

  • 3. Design and synthesis of NAD(P)H: Quinone oxidoreductase (NQO1)-activated prodrugs of 23-hydroxybetulinic acid with enhanced antitumor properties.
    Zhu H, Lu L, Zhu W, Tan Y, Duan Y, Liu J, Ye W, Zhu Z, Xu J, Xu S.
    Eur J Med Chem; 2022 Oct 05; 240():114575. PubMed ID: 35803175
    [Abstract] [Full Text] [Related]

  • 4. NQO1-selective activated prodrugs of combretastatin A-4: Synthesis and biological evaluation.
    Zhang C, Qu Y, Ma X, Li M, Li S, Li Y, Wu L.
    Bioorg Chem; 2020 Oct 05; 103():104200. PubMed ID: 32890998
    [Abstract] [Full Text] [Related]

  • 5. 3-substituted-5-aziridinyl-1-methylindole-4,7-diones as NQO1-directed antitumour agents: mechanism of activation and cytotoxicity in vitro.
    Jaffar M, Phillips RM, Williams KJ, Mrema I, Cole C, Wind NS, Ward TH, Stratford IJ, Patterson AV.
    Biochem Pharmacol; 2003 Oct 01; 66(7):1199-206. PubMed ID: 14505799
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of NQO1-activated prodrugs of podophyllotoxin as antitumor agents.
    Qu Y, Zhang C, Ma X, Gao Y, Liu J, Wu L.
    Bioorg Med Chem; 2020 Dec 15; 28(24):115821. PubMed ID: 33091789
    [Abstract] [Full Text] [Related]

  • 7. Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential.
    Colucci MA, Moody CJ, Couch GD.
    Org Biomol Chem; 2008 Feb 21; 6(4):637-56. PubMed ID: 18264564
    [Abstract] [Full Text] [Related]

  • 8. Betulin-1,4-quinone hybrids: Synthesis, anticancer activity and molecular docking study with NQO1 enzyme.
    Kadela-Tomanek M, Bębenek E, Chrobak E, Marciniec K, Latocha M, Kuśmierz D, Jastrzębska M, Boryczka S.
    Eur J Med Chem; 2019 Sep 01; 177():302-315. PubMed ID: 31158746
    [Abstract] [Full Text] [Related]

  • 9. 2-Substituted 3-methylnaphtho[1,2-b]furan-4,5-diones as novel L-shaped ortho-quinone substrates for NAD(P)H:quinone oxidoreductase (NQO1).
    Bian J, Deng B, Xu L, Xu X, Wang N, Hu T, Yao Z, Du J, Yang L, Lei Y, Li X, Sun H, Zhang X, You Q.
    Eur J Med Chem; 2014 Jul 23; 82():56-67. PubMed ID: 24874653
    [Abstract] [Full Text] [Related]

  • 10. INDQ/NO, a bioreductively activated nitric oxide prodrug.
    Sharma K, Iyer A, Sengupta K, Chakrapani H.
    Org Lett; 2013 Jun 07; 15(11):2636-9. PubMed ID: 23659457
    [Abstract] [Full Text] [Related]

  • 11. Novel anticancer oridonin derivatives possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: Design, synthesis, biological evaluation and nitric oxide release studies.
    Xu S, Wang G, Lin Y, Zhang Y, Pei L, Yao H, Hu M, Qiu Y, Huang Z, Zhang Y, Xu J.
    Bioorg Med Chem Lett; 2016 Jun 15; 26(12):2795-2800. PubMed ID: 27158140
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and biological activity of 1,4-quinone moiety attached to betulin derivatives as potent DT-diaphorase substrate.
    Kadela-Tomanek M, Jastrzębska M, Marciniec K, Chrobak E, Bębenek E, Latocha M, Kuśmierz D, Boryczka S.
    Bioorg Chem; 2021 Jan 15; 106():104478. PubMed ID: 33272711
    [Abstract] [Full Text] [Related]

  • 13. A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent.
    Winski SL, Hargreaves RH, Butler J, Ross D.
    Clin Cancer Res; 1998 Dec 15; 4(12):3083-8. PubMed ID: 9865924
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