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Journal Abstract Search

255 related items for PubMed ID: 28410221

  • 1. Discovery and characterization of small molecule Rac1 inhibitors.
    Arnst JL, Hein AL, Taylor MA, Palermo NY, Contreras JI, Sonawane YA, Wahl AO, Ouellette MM, Natarajan A, Yan Y.
    Oncotarget; 2017 May 23; 8(21):34586-34600. PubMed ID: 28410221
    [Abstract] [Full Text] [Related]

  • 2. Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity.
    Zins K, Gunawardhana S, Lucas T, Abraham D, Aharinejad S.
    J Transl Med; 2013 Nov 27; 11():295. PubMed ID: 24279335
    [Abstract] [Full Text] [Related]

  • 3. R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis.
    Guo Y, Kenney SR, Muller CY, Adams S, Rutledge T, Romero E, Murray-Krezan C, Prekeris R, Sklar LA, Hudson LG, Wandinger-Ness A.
    Mol Cancer Ther; 2015 Oct 27; 14(10):2215-27. PubMed ID: 26206334
    [Abstract] [Full Text] [Related]

  • 4. Maspin controls mammary tumor cell migration through inhibiting Rac1 and Cdc42, but not the RhoA GTPase.
    Shi HY, Stafford LJ, Liu Z, Liu M, Zhang M.
    Cell Motil Cytoskeleton; 2007 May 27; 64(5):338-46. PubMed ID: 17301947
    [Abstract] [Full Text] [Related]

  • 5. Botulinum Toxin A Upregulates Rac1, Cdc42, and RhoA Gene Expression in a Dose-Dependent Manner: In Vivo and in Vitro Study.
    Park TH, Park JH, Chang CH, Rah DK.
    J Craniofac Surg; 2016 Mar 27; 27(2):516-20. PubMed ID: 26963302
    [Abstract] [Full Text] [Related]

  • 6. A role for Gab1/SHP2 in thrombin activation of PAK1: gene transfer of kinase-dead PAK1 inhibits injury-induced restenosis.
    Wang D, Paria BC, Zhang Q, Karpurapu M, Li Q, Gerthoffer WT, Nakaoka Y, Rao GN.
    Circ Res; 2009 May 08; 104(9):1066-75. PubMed ID: 19359598
    [Abstract] [Full Text] [Related]

  • 7. Emodin inhibits tumor cell migration through suppression of the phosphatidylinositol 3-kinase-Cdc42/Rac1 pathway.
    Huang Q, Shen HM, Ong CN.
    Cell Mol Life Sci; 2005 May 08; 62(10):1167-75. PubMed ID: 15928809
    [Abstract] [Full Text] [Related]

  • 8. A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice.
    Zins K, Lucas T, Reichl P, Abraham D, Aharinejad S.
    PLoS One; 2013 May 08; 8(9):e74924. PubMed ID: 24040362
    [Abstract] [Full Text] [Related]

  • 9. Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases.
    Oprea TI, Sklar LA, Agola JO, Guo Y, Silberberg M, Roxby J, Vestling A, Romero E, Surviladze Z, Murray-Krezan C, Waller A, Ursu O, Hudson LG, Wandinger-Ness A.
    PLoS One; 2015 May 08; 10(11):e0142182. PubMed ID: 26558612
    [Abstract] [Full Text] [Related]

  • 10. Differential role of Rho GTPases in intestinal epithelial barrier regulation in vitro.
    Schlegel N, Meir M, Spindler V, Germer CT, Waschke J.
    J Cell Physiol; 2011 May 08; 226(5):1196-203. PubMed ID: 20945370
    [Abstract] [Full Text] [Related]

  • 11. Regulation of osteoclast apoptosis and motility by small GTPase binding protein Rac1.
    Fukuda A, Hikita A, Wakeyama H, Akiyama T, Oda H, Nakamura K, Tanaka S.
    J Bone Miner Res; 2005 Dec 08; 20(12):2245-53. PubMed ID: 16294277
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of the Rho GTPase, Rac1, decreases estrogen receptor levels and is a novel therapeutic strategy in breast cancer.
    Rosenblatt AE, Garcia MI, Lyons L, Xie Y, Maiorino C, Désiré L, Slingerland J, Burnstein KL.
    Endocr Relat Cancer; 2011 Apr 08; 18(2):207-19. PubMed ID: 21118977
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTOR.
    Chen SM, Liu JL, Wang X, Liang C, Ding J, Meng LH.
    Biochem Pharmacol; 2012 May 01; 83(9):1183-94. PubMed ID: 22305748
    [Abstract] [Full Text] [Related]

  • 14. Saponins extracted from by-product of Asparagus officinalis L. suppress tumour cell migration and invasion through targeting Rho GTPase signalling pathway.
    Wang J, Liu Y, Zhao J, Zhang W, Pang X.
    J Sci Food Agric; 2013 Apr 01; 93(6):1492-8. PubMed ID: 23450726
    [Abstract] [Full Text] [Related]

  • 15. Identification of H-Ras, RhoA, Rac1 and Cdc42 responsive genes.
    Teramoto H, Malek RL, Behbahani B, Castellone MD, Lee NH, Gutkind JS.
    Oncogene; 2003 May 01; 22(17):2689-97. PubMed ID: 12730683
    [Abstract] [Full Text] [Related]

  • 16. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
    Boissier P, Huynh-Do U.
    Cell Signal; 2014 Mar 01; 26(3):483-91. PubMed ID: 24308970
    [Abstract] [Full Text] [Related]

  • 17. Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways.
    Jaffe T, Schwartz B.
    Int J Cancer; 2008 Dec 01; 123(11):2543-56. PubMed ID: 18767036
    [Abstract] [Full Text] [Related]

  • 18. Rho guanosine 5'-triphosphatases differentially regulate insulin-like growth factor I (IGF-I) receptor-dependent and -independent actions of IGF-II on human trophoblast migration.
    Shields SK, Nicola C, Chakraborty C.
    Endocrinology; 2007 Oct 01; 148(10):4906-17. PubMed ID: 17640993
    [Abstract] [Full Text] [Related]

  • 19. RAC1 GTP-ase signals Wnt-beta-catenin pathway mediated integrin-directed metastasis-associated tumor cell phenotypes in triple negative breast cancers.
    De P, Carlson JH, Jepperson T, Willis S, Leyland-Jones B, Dey N.
    Oncotarget; 2017 Jan 10; 8(2):3072-3103. PubMed ID: 27902969
    [Abstract] [Full Text] [Related]

  • 20. Epigenetically upregulated GEFT-derived invasion and metastasis of rhabdomyosarcoma via epithelial mesenchymal transition promoted by the Rac1/Cdc42-PAK signalling pathway.
    Liu C, Zhang L, Cui W, Du J, Li Z, Pang Y, Liu Q, Shang H, Meng L, Li W, Song L, Wang P, Xie Y, Wang Y, Liu Y, Hu J, Zhang W, Li F.
    EBioMedicine; 2019 Dec 10; 50():122-134. PubMed ID: 31761617
    [Abstract] [Full Text] [Related]

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