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Journal Abstract Search

179 related items for PubMed ID: 2846195

  • 1. Superoxide dismutase-mediated reversible conversion of 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole, the N-hydroxy derivative of Trp-P-2, into its nitroso derivative.
    Hiramoto K, Negishi K, Namba T, Katsu T, Hayatsu H.
    Carcinogenesis; 1988 Nov; 9(11):2003-8. PubMed ID: 2846195
    [Abstract] [Full Text] [Related]

  • 2. Iron-chlorophyllin-mediated conversion of 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2(NHOH)) into its nitroso derivative.
    Arimoto-Kobayashi S, Inada N, Nakano H, Rai H, Hayatsu H.
    Mutat Res; 1998 May 25; 400(1-2):259-69. PubMed ID: 9685672
    [Abstract] [Full Text] [Related]

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  • 4. DNA strand cleavage in vitro by 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]-indole, a direct-acting mutagen formed in the metabolism of carcinogenic 3-amino-1-methyl-5H-pyrido[4,3-b]indole.
    Wakata A, Oka N, Hiramoto K, Yoshioka A, Negishi K, Wataya Y, Hayatsu H.
    Cancer Res; 1985 Nov 25; 45(11 Pt 2):5867-71. PubMed ID: 4053057
    [Abstract] [Full Text] [Related]

  • 5. Generation of intracellular active oxygens in mouse FM3A cells by 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole, the activated Trp-P-2.
    Wataya Y, Yamane K, Hiramoto K, Ohtsuka Y, Okubata Y, Negishi K, Hayatsu H.
    Jpn J Cancer Res; 1988 May 25; 79(5):576-9. PubMed ID: 2841270
    [Abstract] [Full Text] [Related]

  • 6. Activation and detoxication of N-hydroxy-Trp-P-2 by glutathione and glutathione transferases.
    Saito K, Yamazoe Y, Kamataki T, Kato R.
    Carcinogenesis; 1983 Dec 25; 4(12):1551-7. PubMed ID: 6360405
    [Abstract] [Full Text] [Related]

  • 7. Chemical modification of DNA with muta-carcinogens. I. 3-Amino-1-methyl-5H-pyrido[4,3-b]indole and 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole: metabolic activation and structure of the DNA adducts.
    Hashimoto Y, Shudo K.
    Environ Health Perspect; 1985 Oct 25; 62():209-14. PubMed ID: 4085425
    [Abstract] [Full Text] [Related]

  • 8. Mechanism of activation of proximate mutagens in Ames' tester strains: the acetyl-CoA dependent enzyme in Salmonella typhimurium TA98 deficient in TA98/1,8-DNP6 catalyzes DNA-binding as the cause of mutagenicity.
    Saito K, Yamazoe Y, Kamataki T, Kato R.
    Biochem Biophys Res Commun; 1983 Oct 14; 116(1):141-7. PubMed ID: 6357194
    [Abstract] [Full Text] [Related]

  • 9. Inhibitory effect of chlorophyll on the genotoxicity of 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2).
    Negishi T, Arimoto S, Nishizaki C, Hayatsu H.
    Carcinogenesis; 1989 Jan 14; 10(1):145-9. PubMed ID: 2491967
    [Abstract] [Full Text] [Related]

  • 10. Role of hemin in the inhibition of mutagenic activity of 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) and other aminoazaarenes.
    Arimoto S, Hayatsu H.
    Mutat Res; 1989 Aug 14; 213(2):217-26. PubMed ID: 2668748
    [Abstract] [Full Text] [Related]

  • 11. Induction of DNA recombination by activated 3-amino-1-methyl-5H-pyrido[4,3-b]indole.
    Hiramoto K, Kanamitsu S, Negishi K, Ikeda H, Hayatsu H.
    Jpn J Cancer Res; 1995 Feb 14; 86(2):155-9. PubMed ID: 7730138
    [Abstract] [Full Text] [Related]

  • 12. Reactions of potent mutagens, 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) and 2-amino-6-methyl-dipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1) with nucleic acid.
    Hashimoto Y, Shudo K, Imamura M, Okamoto T.
    Nucleic Acids Symp Ser; 1980 Feb 14; (8):s109-12. PubMed ID: 7255181
    [Abstract] [Full Text] [Related]

  • 13. In vitro binding of potent mutagenic pyrolysates to intestinal bacteria.
    Morotomi M, Mutai M.
    J Natl Cancer Inst; 1986 Jul 14; 77(1):195-201. PubMed ID: 3014197
    [Abstract] [Full Text] [Related]

  • 14. In vitro reaction of hydroxyamino derivatives of MeIQx, Glu-P-1 and Trp-P-1 with DNA: 32P-postlabelling analysis of DNA adducts formed in vivo by the parent amines and in vitro by their hydroxyamino derivatives.
    Yamashita K, Umemoto A, Grivas S, Kato S, Sugimura T.
    Mutagenesis; 1988 Nov 14; 3(6):515-20. PubMed ID: 3070292
    [Abstract] [Full Text] [Related]

  • 15. Structural elucidation of a mutagenic metabolite of 3-amino-1-methyl-5H-pyrido[4,3-b]indole.
    Yamazoe Y, Ishii K, Kamataki T, Kato R.
    Drug Metab Dispos; 1981 Nov 14; 9(3):292-6. PubMed ID: 6113943
    [Abstract] [Full Text] [Related]

  • 16. Suppression of genotoxicity of carcinogens by (-)-epigallocatechin gallate.
    Hayatsu H, Inada N, Kakutani T, Arimoto S, Negishi T, Mori K, Okuda T, Sakata I.
    Prev Med; 1992 May 14; 21(3):370-6. PubMed ID: 1614998
    [Abstract] [Full Text] [Related]

  • 17. Glutathione transferase-mediated and non-enzymatic activation and detoxication of the N-hydroxy derivative of Trp-P-2, a potent pyrolysate promutagen.
    Saito K, Yamazoe Y, Kamataki T, Kato R.
    Xenobiotica; 1984 Jul 14; 14(7):545-8. PubMed ID: 6506768
    [Abstract] [Full Text] [Related]

  • 18. DNA binding of N-hydroxy-Trp-P-2 and N-hydroxy-Glu-P-1 by acetyl-CoA dependent enzyme in mammalian liver cytosol.
    Shinohara A, Saito K, Yamazoe Y, Kamataki T, Kato R.
    Carcinogenesis; 1985 Feb 14; 6(2):305-7. PubMed ID: 3971494
    [Abstract] [Full Text] [Related]

  • 19. Oxidation of the 2-hydroxyamino derivative of 2-amino-6-methyl-dipyrido[1,2-a: 3',2'-d] imidazole (Glu-P-1) to its 2-nitroso form, an ultimate form reacting with hemoglobin thiol groups.
    Umemoto A, Monden Y, Tsuda M, Grivas S, Sugimura T.
    Biochem Biophys Res Commun; 1988 Mar 30; 151(3):1326-31. PubMed ID: 3355558
    [Abstract] [Full Text] [Related]

  • 20. Modified metabolism of a carcinogen, 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2), by liver S9 from Schistosoma japonicum-infected mice.
    Arimoto S, Matsuoka H, Aji T, Ishii A, Wataya Y, Hayatsu H.
    Mutat Res; 1992 Jul 30; 282(3):177-82. PubMed ID: 1378550
    [Abstract] [Full Text] [Related]

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