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250 related items for PubMed ID: 28462819

  • 1. Human ESC/iPSC-Derived Hepatocyte-like Cells Achieve Zone-Specific Hepatic Properties by Modulation of WNT Signaling.
    Mitani S, Takayama K, Nagamoto Y, Imagawa K, Sakurai F, Tachibana M, Sumazaki R, Mizuguchi H.
    Mol Ther; 2017 Jun 07; 25(6):1420-1433. PubMed ID: 28462819
    [Abstract] [Full Text] [Related]

  • 2. [Generation of Zone-specific Hepatocyte-like Cells from Human Induced Pluripotent Stem Cells for Accurate Prediction of Drug-induced Hepatotoxicity].
    Mitani S.
    Yakugaku Zasshi; 2019 Jun 07; 139(12):1509-1512. PubMed ID: 31787637
    [Abstract] [Full Text] [Related]

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  • 4. Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction.
    Nakamori D, Takayama K, Nagamoto Y, Mitani S, Sakurai F, Tachibana M, Mizuguchi H.
    Biochem Biophys Res Commun; 2016 Jan 15; 469(3):424-9. PubMed ID: 26679606
    [Abstract] [Full Text] [Related]

  • 5. Scalable Differentiation of Human iPSCs in a Multicellular Spheroid-based 3D Culture into Hepatocyte-like Cells through Direct Wnt/β-catenin Pathway Inhibition.
    Pettinato G, Ramanathan R, Fisher RA, Mangino MJ, Zhang N, Wen X.
    Sci Rep; 2016 Sep 12; 6():32888. PubMed ID: 27616299
    [Abstract] [Full Text] [Related]

  • 6. Human induced hepatic lineage-oriented stem cells: autonomous specification of human iPS cells toward hepatocyte-like cells without any exogenous differentiation factors.
    Ishikawa T, Kobayashi M, Yanagi S, Kato C, Takashima R, Kobayashi E, Hagiwara K, Ochiya T.
    PLoS One; 2015 Sep 12; 10(4):e0123193. PubMed ID: 25875613
    [Abstract] [Full Text] [Related]

  • 7. Differentiation of human foreskin fibroblast-derived induced pluripotent stem cells into hepatocyte-like cells.
    Wang J, Zhao P, Wan Z, Jin X, Cheng Y, Yan T, Qing S, Ding N, Xin S.
    Cell Biochem Funct; 2016 Oct 12; 34(7):475-482. PubMed ID: 27569862
    [Abstract] [Full Text] [Related]

  • 8. Comparative analysis of human embryonic stem cell and induced pluripotent stem cell-derived hepatocyte-like cells reveals current drawbacks and possible strategies for improved differentiation.
    Jozefczuk J, Prigione A, Chavez L, Adjaye J.
    Stem Cells Dev; 2011 Jul 12; 20(7):1259-75. PubMed ID: 21162674
    [Abstract] [Full Text] [Related]

  • 9. Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.
    Heslop JA, Kia R, Pridgeon CS, Sison-Young RL, Liloglou T, Elmasry M, Fenwick SW, Mills JS, Kitteringham NR, Goldring CE, Park BK.
    Stem Cells Transl Med; 2017 May 12; 6(5):1321-1331. PubMed ID: 28456008
    [Abstract] [Full Text] [Related]

  • 10. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells.
    Song Z, Cai J, Liu Y, Zhao D, Yong J, Duo S, Song X, Guo Y, Zhao Y, Qin H, Yin X, Wu C, Che J, Lu S, Ding M, Deng H.
    Cell Res; 2009 Nov 12; 19(11):1233-42. PubMed ID: 19736565
    [Abstract] [Full Text] [Related]

  • 11. Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes.
    Huang J, Guo X, Li W, Zhang H.
    Sci Rep; 2017 Jan 17; 7():40716. PubMed ID: 28094799
    [Abstract] [Full Text] [Related]

  • 12. Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.
    Takayama K, Inamura M, Kawabata K, Katayama K, Higuchi M, Tashiro K, Nonaka A, Sakurai F, Hayakawa T, Furue MK, Mizuguchi H.
    Mol Ther; 2012 Jan 17; 20(1):127-37. PubMed ID: 22068426
    [Abstract] [Full Text] [Related]

  • 13.
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  • 14. Dual modulation of human hepatic zonation via canonical and non-canonical Wnt pathways.
    McEnerney L, Duncan K, Bang BR, Elmasry S, Li M, Miki T, Ramakrishnan SK, Shah YM, Saito T.
    Exp Mol Med; 2017 Dec 15; 49(12):e413. PubMed ID: 29244788
    [Abstract] [Full Text] [Related]

  • 15. Factors from human embryonic stem cell-derived fibroblast-like cells promote topology-dependent hepatic differentiation in primate embryonic and induced pluripotent stem cells.
    Huang HP, Yu CY, Chen HF, Chen PH, Chuang CY, Lin SJ, Huang ST, Chan WH, Ueng TH, Ho HN, Kuo HC.
    J Biol Chem; 2010 Oct 22; 285(43):33510-33519. PubMed ID: 20720011
    [Abstract] [Full Text] [Related]

  • 16. Lipidomic profiling of patient-specific iPSC-derived hepatocyte-like cells.
    Kiamehr M, Viiri LE, Vihervaara T, Koistinen KM, Hilvo M, Ekroos K, Käkelä R, Aalto-Setälä K.
    Dis Model Mech; 2017 Sep 01; 10(9):1141-1153. PubMed ID: 28733363
    [Abstract] [Full Text] [Related]

  • 17. Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes.
    Takayama K, Morisaki Y, Kuno S, Nagamoto Y, Harada K, Furukawa N, Ohtaka M, Nishimura K, Imagawa K, Sakurai F, Tachibana M, Sumazaki R, Noguchi E, Nakanishi M, Hirata K, Kawabata K, Mizuguchi H.
    Proc Natl Acad Sci U S A; 2014 Nov 25; 111(47):16772-7. PubMed ID: 25385620
    [Abstract] [Full Text] [Related]

  • 18. Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells.
    Calabrese D, Roma G, Bergling S, Carbone W, Mele V, Nuciforo S, Fofana I, Campana B, Szkolnicka D, Hay DC, Tchorz J, Bouwmeester T, Wieland S, Heim MH.
    PLoS One; 2019 Nov 25; 14(8):e0221762. PubMed ID: 31465481
    [Abstract] [Full Text] [Related]

  • 19. Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction.
    Takayama K, Inamura M, Kawabata K, Sugawara M, Kikuchi K, Higuchi M, Nagamoto Y, Watanabe H, Tashiro K, Sakurai F, Hayakawa T, Furue MK, Mizuguchi H.
    J Hepatol; 2012 Sep 25; 57(3):628-36. PubMed ID: 22659344
    [Abstract] [Full Text] [Related]

  • 20. Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells.
    Ulvestad M, Nordell P, Asplund A, Rehnström M, Jacobsson S, Holmgren G, Davidson L, Brolén G, Edsbagge J, Björquist P, Küppers-Munther B, Andersson TB.
    Biochem Pharmacol; 2013 Sep 01; 86(5):691-702. PubMed ID: 23856292
    [Abstract] [Full Text] [Related]

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