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Journal Abstract Search

524 related items for PubMed ID: 28462840

  • 1. Synthesis and biological evaluation of N-(carbobenzyloxy)-l-phenylalanine and N-(carbobenzyloxy)-l-aspartic acid-β-benzyl ester derivatives as potent topoisomerase IIα inhibitors.
    Han X, Zhong Y, Zhou G, Qi H, Li S, Ding Q, Liu Z, Song Y, Qiao X.
    Bioorg Med Chem; 2017 Jun 15; 25(12):3116-3126. PubMed ID: 28462840
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, cytotoxicity, HuTopoIIα inhibitory activity and molecular docking studies of pyrazole derivatives as potential anticancer agents.
    Alam R, Wahi D, Singh R, Sinha D, Tandon V, Grover A, Rahisuddin.
    Bioorg Chem; 2016 Dec 15; 69():77-90. PubMed ID: 27744115
    [Abstract] [Full Text] [Related]

  • 3. Hydroxylated 2,4-diphenyl indenopyridine derivatives as a selective non-intercalative topoisomerase IIα catalytic inhibitor.
    Kadayat TM, Park C, Jun KY, Thapa Magar TB, Bist G, Yoo HY, Kwon Y, Lee ES.
    Eur J Med Chem; 2015 Jan 27; 90():302-14. PubMed ID: 25437617
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of friedelan triterpenoid analogs with DNA topoisomerase IIα inhibitory activity and their molecular docking studies.
    Mandal A, Ghosh S, Bothra AK, Nanda AK, Ghosh P.
    Eur J Med Chem; 2012 Aug 27; 54():137-43. PubMed ID: 22633831
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure-activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor.
    Ahmad P, Woo H, Jun KY, Kadi AA, Abdel-Aziz HA, Kwon Y, Rahman AF.
    Bioorg Med Chem; 2016 Apr 15; 24(8):1898-908. PubMed ID: 26988802
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor.
    Jun KY, Lee EY, Jung MJ, Lee OH, Lee ES, Park Choo HY, Na Y, Kwon Y.
    Eur J Med Chem; 2011 Jun 15; 46(6):1964-71. PubMed ID: 21419530
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  • 7. Synthesis, Biological Evaluation and Molecular Docking Study of Cyclic Diarylheptanoids as Potential Anticancer Therapeutics.
    Lu Y, Yin W, Alam MS, Kadi AA, Jahng Y, Kwon Y, Rahman AFMM.
    Anticancer Agents Med Chem; 2020 Jun 15; 20(4):464-475. PubMed ID: 31763968
    [Abstract] [Full Text] [Related]

  • 8. Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIα, G-quadruplex binding and cytotoxic properties.
    Palluotto F, Sosic A, Pinato O, Zoidis G, Catto M, Sissi C, Gatto B, Carotti A.
    Eur J Med Chem; 2016 Nov 10; 123():704-717. PubMed ID: 27521587
    [Abstract] [Full Text] [Related]

  • 9. Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors.
    Park S, Kadayat TM, Jun KY, Thapa Magar TB, Bist G, Shrestha A, Lee ES, Kwon Y.
    Eur J Med Chem; 2017 Jan 05; 125():14-28. PubMed ID: 27643560
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors.
    El-Adl K, El-Helby AA, Sakr H, Elwan A.
    Bioorg Chem; 2020 Dec 05; 105():104399. PubMed ID: 33113414
    [Abstract] [Full Text] [Related]

  • 11. 3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage.
    Park SE, Chang IH, Jun KY, Lee E, Lee ES, Na Y, Kwon Y.
    Eur J Med Chem; 2013 Nov 05; 69():139-45. PubMed ID: 24013413
    [Abstract] [Full Text] [Related]

  • 12. Topoisomerase IIα inhibitory and antiproliferative activity of dihydroxylated 2,6-diphenyl-4-fluorophenylpyridines: Design, synthesis, and structure-activity relationships.
    Kunwar S, Hwang SY, Katila P, Man Kadayat T, Jung AR, Kwon Y, Lee ES.
    Bioorg Med Chem Lett; 2022 Mar 15; 60():128606. PubMed ID: 35123005
    [Abstract] [Full Text] [Related]

  • 13. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE, Gedawy EM.
    Eur J Med Chem; 2018 Apr 25; 150():403-418. PubMed ID: 29547830
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, computational quantum chemical study, in silico ADMET and molecular docking analysis, in vitro biological evaluation of a novel sulfur heterocyclic thiophene derivative containing 1,2,3-triazole and pyridine moieties as a potential human topoisomerase IIα inhibiting anticancer agent.
    Murugavel S, Ravikumar C, Jaabil G, Alagusundaram P.
    Comput Biol Chem; 2019 Apr 25; 79():73-82. PubMed ID: 30731361
    [Abstract] [Full Text] [Related]

  • 15. Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα.
    Minniti E, Byl JAW, Riccardi L, Sissi C, Rosini M, De Vivo M, Minarini A, Osheroff N.
    Bioorg Med Chem Lett; 2017 Oct 15; 27(20):4687-4693. PubMed ID: 28919339
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and biological evaluation of imidazopyridinyl-1,3,4-oxadiazole conjugates as apoptosis inducers and topoisomerase IIα inhibitors.
    Subba Rao AV, Vishnu Vardhan MV, Subba Reddy NV, Srinivasa Reddy T, Shaik SP, Bagul C, Kamal A.
    Bioorg Chem; 2016 Dec 15; 69():7-19. PubMed ID: 27656775
    [Abstract] [Full Text] [Related]

  • 17. N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIα and induce apoptosis in G1/S phase.
    Baviskar AT, Madaan C, Preet R, Mohapatra P, Jain V, Agarwal A, Guchhait SK, Kundu CN, Banerjee UC, Bharatam PV.
    J Med Chem; 2011 Jul 28; 54(14):5013-30. PubMed ID: 21644529
    [Abstract] [Full Text] [Related]

  • 18. Synthesis, biological evaluation and modeling studies of terphenyl topoisomerase IIα inhibitors as anticancer agents.
    Qiu J, Zhao B, Zhong W, Shen Y, Lin H.
    Eur J Med Chem; 2015 Apr 13; 94():427-35. PubMed ID: 25800514
    [Abstract] [Full Text] [Related]

  • 19. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    Reddy VG, Bonam SR, Reddy TS, Akunuri R, Naidu VGM, Nayak VL, Bhargava SK, Kumar HMS, Srihari P, Kamal A.
    Eur J Med Chem; 2018 Jan 20; 144():595-611. PubMed ID: 29289884
    [Abstract] [Full Text] [Related]

  • 20. Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction.
    Tokala R, Mahajan S, Kiranmai G, Sigalapalli DK, Sana S, John SE, Nagesh N, Shankaraiah N.
    Bioorg Chem; 2021 Jan 20; 106():104481. PubMed ID: 33261848
    [Abstract] [Full Text] [Related]

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