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922 related items for PubMed ID: 28478343

  • 1. Rational design, synthesis and biological screening of triazine-triazolopyrimidine hybrids as multitarget anti-Alzheimer agents.
    Jameel E, Meena P, Maqbool M, Kumar J, Ahmed W, Mumtazuddin S, Tiwari M, Hoda N, Jayaram B.
    Eur J Med Chem; 2017 Aug 18; 136():36-51. PubMed ID: 28478343
    [Abstract] [Full Text] [Related]

  • 2. Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents.
    Maqbool M, Manral A, Jameel E, Kumar J, Saini V, Shandilya A, Tiwari M, Hoda N, Jayaram B.
    Bioorg Med Chem; 2016 Jun 15; 24(12):2777-88. PubMed ID: 27157006
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  • 3. Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
    Riazimontazer E, Sadeghpour H, Nadri H, Sakhteman A, Tüylü Küçükkılınç T, Miri R, Edraki N.
    Bioorg Chem; 2019 Aug 15; 89():103006. PubMed ID: 31158577
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  • 4. Multifunctional novel Diallyl disulfide (DADS) derivatives with β-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer's disease.
    Manral A, Saini V, Meena P, Tiwari M.
    Bioorg Med Chem; 2015 Oct 01; 23(19):6389-403. PubMed ID: 26337018
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  • 5. Synthesis and screening of triazolopyrimidine scaffold as multi-functional agents for Alzheimer's disease therapies.
    Kumar J, Meena P, Singh A, Jameel E, Maqbool M, Mobashir M, Shandilya A, Tiwari M, Hoda N, Jayaram B.
    Eur J Med Chem; 2016 Aug 25; 119():260-77. PubMed ID: 27227482
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  • 6. Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.
    Makhaeva GF, Lushchekina SV, Kovaleva NV, Yu Astakhova T, Boltneva NP, Rudakova EV, Serebryakova OG, Proshin AN, Serkov IV, Trofimova TP, Tafeenko VA, Radchenko EV, Palyulin VA, Fisenko VP, Korábečný J, Soukup O, Richardson RJ.
    Bioorg Chem; 2021 Jul 25; 112():104974. PubMed ID: 34029971
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  • 7. Design, synthesis and evaluation of novel 4-dimethylamine flavonoid derivatives as potential multi-functional anti-Alzheimer agents.
    Luo W, Su YB, Hong C, Tian RG, Su LP, Wang YQ, Li Y, Yue JJ, Wang CJ.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7275-82. PubMed ID: 24148835
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  • 8. Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase.
    Catto M, Berezin AA, Lo Re D, Loizou G, Demetriades M, De Stradis A, Campagna F, Koutentis PA, Carotti A.
    Eur J Med Chem; 2012 Dec 01; 58():84-97. PubMed ID: 23108363
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS, Xie SS, Li SY, Pan LF, Wang XB, Kong LY.
    Bioorg Med Chem; 2014 Nov 01; 22(21):6089-104. PubMed ID: 25282654
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  • 10. Tetrahydroacridine derivatives with dichloronicotinic acid moiety as attractive, multipotent agents for Alzheimer's disease treatment.
    Czarnecka K, Chufarova N, Halczuk K, Maciejewska K, Girek M, Skibiński R, Jończyk J, Bajda M, Kabziński J, Majsterek I, Szymański P.
    Eur J Med Chem; 2018 Feb 10; 145():760-769. PubMed ID: 29353726
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  • 11. 1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease.
    Wichur T, Więckowska A, Więckowski K, Godyń J, Jończyk J, Valdivieso ÁDR, Panek D, Pasieka A, Sabaté R, Knez D, Gobec S, Malawska B.
    Eur J Med Chem; 2020 Feb 01; 187():111916. PubMed ID: 31812794
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  • 12. Tacrine-hydroxamate derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
    Xu A, He F, Zhang X, Li X, Ran Y, Wei C, James Chou C, Zhang R, Wu J.
    Bioorg Chem; 2020 May 01; 98():103721. PubMed ID: 32193030
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  • 13. Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
    Shan WJ, Huang L, Zhou Q, Meng FC, Li XS.
    Eur J Med Chem; 2011 Dec 01; 46(12):5885-93. PubMed ID: 22019228
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  • 14. Synthesis and evaluation of 7,8-dehydrorutaecarpine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
    He Y, Yao PF, Chen SB, Huang ZH, Huang SL, Tan JH, Li D, Gu LQ, Huang ZS.
    Eur J Med Chem; 2013 May 01; 63():299-312. PubMed ID: 23501115
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Bolea I, Juárez-Jiménez J, de Los Ríos C, Chioua M, Pouplana R, Luque FJ, Unzeta M, Marco-Contelles J, Samadi A.
    J Med Chem; 2011 Dec 22; 54(24):8251-70. PubMed ID: 22023459
    [Abstract] [Full Text] [Related]

  • 16. Novel chromanone-dithiocarbamate hybrids as multifunctional AChE inhibitors with β-amyloid anti-aggregation properties for the treatment of Alzheimer's disease.
    Jiang N, Ding J, Liu J, Sun X, Zhang Z, Mo Z, Li X, Yin H, Tang W, Xie SS.
    Bioorg Chem; 2019 Aug 22; 89():103027. PubMed ID: 31176237
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  • 17. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J, Yang H, Chen Y, Lin H, Li Q, Mo J, Bian Y, Pei Y, Sun H.
    J Enzyme Inhib Med Chem; 2018 Dec 22; 33(1):496-506. PubMed ID: 29405075
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  • 18. Novel deoxyvasicinone derivatives as potent multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
    Ma F, Du H.
    Eur J Med Chem; 2017 Nov 10; 140():118-127. PubMed ID: 28923380
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  • 19. Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease.
    Bowroju SK, Penthala NR, Lakkaniga NR, Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ, Crooks PA.
    Bioorg Med Chem; 2021 Sep 01; 45():116311. PubMed ID: 34304133
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  • 20. Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents.
    Shaik JB, Palaka BK, Penumala M, Kotapati KV, Devineni SR, Eadlapalli S, Darla MM, Ampasala DR, Vadde R, Amooru GD.
    Eur J Med Chem; 2016 Jan 01; 107():219-32. PubMed ID: 26588065
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