These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Analysis of the repaglinide concentration increase produced by gemfibrozil and itraconazole based on the inhibition of the hepatic uptake transporter and metabolic enzymes. Kudo T, Hisaka A, Sugiyama Y, Ito K. Drug Metab Dispos; 2013 Feb; 41(2):362-71. PubMed ID: 23139378 [Abstract] [Full Text] [Related]
6. Implications of intercorrelation between hepatic CYP3A4-CYP2C8 enzymes for the evaluation of drug-drug interactions: a case study with repaglinide. Doki K, Darwich AS, Achour B, Tornio A, Backman JT, Rostami-Hodjegan A. Br J Clin Pharmacol; 2018 May; 84(5):972-986. PubMed ID: 29381228 [Abstract] [Full Text] [Related]
8. Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions. Izumi S, Nozaki Y, Maeda K, Komori T, Takenaka O, Kusuhara H, Sugiyama Y. Drug Metab Dispos; 2015 Feb; 43(2):235-47. PubMed ID: 25414411 [Abstract] [Full Text] [Related]
10. Quantitative prediction of repaglinide-rifampicin complex drug interactions using dynamic and static mechanistic models: delineating differential CYP3A4 induction and OATP1B1 inhibition potential of rifampicin. Varma MV, Lin J, Bi YA, Rotter CJ, Fahmi OA, Lam JL, El-Kattan AF, Goosen TC, Lai Y. Drug Metab Dispos; 2013 May; 41(5):966-74. PubMed ID: 23393219 [Abstract] [Full Text] [Related]
12. Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole. Türk D, Hanke N, Wolf S, Frechen S, Eissing T, Wendl T, Schwab M, Lehr T. Clin Pharmacokinet; 2019 Dec; 58(12):1595-1607. PubMed ID: 31129789 [Abstract] [Full Text] [Related]
15. Interplay of UDP-Glucuronosyltransferase and CYP2C8 for CYP2C8 Mediated Drug Oxidation and Its Impact on Drug-Drug Interaction Produced by Standardized CYP2C8 Inhibitors, Clopidogrel and Gemfibrozil. Iga K, Kiriyama A. Clin Pharmacokinet; 2024 Jan; 63(1):43-56. PubMed ID: 37921907 [Abstract] [Full Text] [Related]
18. Dose-dependent interaction between gemfibrozil and repaglinide in humans: strong inhibition of CYP2C8 with subtherapeutic gemfibrozil doses. Honkalammi J, Niemi M, Neuvonen PJ, Backman JT. Drug Metab Dispos; 2011 Oct; 39(10):1977-86. PubMed ID: 21778352 [Abstract] [Full Text] [Related]
19. Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes. Marzolini C, Rajoli R, Battegay M, Elzi L, Back D, Siccardi M. Clin Pharmacokinet; 2017 Apr; 56(4):409-420. PubMed ID: 27599706 [Abstract] [Full Text] [Related]
20. Physiologically Based Pharmacokinetic (PBPK) Modeling of Pitavastatin and Atorvastatin to Predict Drug-Drug Interactions (DDIs). Duan P, Zhao P, Zhang L. Eur J Drug Metab Pharmacokinet; 2017 Aug; 42(4):689-705. PubMed ID: 27858342 [Abstract] [Full Text] [Related] Page: [Next] [New Search]