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626 related items for PubMed ID: 28483909

  • 1. Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson-Gilford Progeria Syndrome.
    Wheaton K, Campuzano D, Ma W, Sheinis M, Ho B, Brown GW, Benchimol S.
    Mol Cell Biol; 2017 Jul 15; 37(14):. PubMed ID: 28483909
    [Abstract] [Full Text] [Related]

  • 2. Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence.
    Benson EK, Lee SW, Aaronson SA.
    J Cell Sci; 2010 Aug 01; 123(Pt 15):2605-12. PubMed ID: 20605919
    [Abstract] [Full Text] [Related]

  • 3. Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p53.
    Kudlow BA, Stanfel MN, Burtner CR, Johnston ED, Kennedy BK.
    Mol Biol Cell; 2008 Dec 01; 19(12):5238-48. PubMed ID: 18843043
    [Abstract] [Full Text] [Related]

  • 4. Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome.
    Finley J.
    Med Hypotheses; 2018 Sep 01; 118():151-162. PubMed ID: 30037605
    [Abstract] [Full Text] [Related]

  • 5. Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture.
    Rivera-Torres J, Acín-Perez R, Cabezas-Sánchez P, Osorio FG, Gonzalez-Gómez C, Megias D, Cámara C, López-Otín C, Enríquez JA, Luque-García JL, Andrés V.
    J Proteomics; 2013 Oct 08; 91():466-77. PubMed ID: 23969228
    [Abstract] [Full Text] [Related]

  • 6. Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes.
    Kreienkamp R, Croke M, Neumann MA, Bedia-Diaz G, Graziano S, Dusso A, Dorsett D, Carlberg C, Gonzalo S.
    Oncotarget; 2016 May 24; 7(21):30018-31. PubMed ID: 27145372
    [Abstract] [Full Text] [Related]

  • 7. Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.
    Chojnowski A, Ong PF, Wong ES, Lim JS, Mutalif RA, Navasankari R, Dutta B, Yang H, Liow YY, Sze SK, Boudier T, Wright GD, Colman A, Burke B, Stewart CL, Dreesen O.
    Elife; 2015 Aug 27; 4():. PubMed ID: 26312502
    [Abstract] [Full Text] [Related]

  • 8. Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts.
    Cao K, Blair CD, Faddah DA, Kieckhaefer JE, Olive M, Erdos MR, Nabel EG, Collins FS.
    J Clin Invest; 2011 Jul 27; 121(7):2833-44. PubMed ID: 21670498
    [Abstract] [Full Text] [Related]

  • 9. Progerin sequestration of PCNA promotes replication fork collapse and mislocalization of XPA in laminopathy-related progeroid syndromes.
    Hilton BA, Liu J, Cartwright BM, Liu Y, Breitman M, Wang Y, Jones R, Tang H, Rusinol A, Musich PR, Zou Y.
    FASEB J; 2017 Sep 27; 31(9):3882-3893. PubMed ID: 28515154
    [Abstract] [Full Text] [Related]

  • 10. Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations.
    Gonzalo S, Kreienkamp R, Askjaer P.
    Ageing Res Rev; 2017 Jan 27; 33():18-29. PubMed ID: 27374873
    [Abstract] [Full Text] [Related]

  • 11. p53 isoforms regulate premature aging in human cells.
    von Muhlinen N, Horikawa I, Alam F, Isogaya K, Lissa D, Vojtesek B, Lane DP, Harris CC.
    Oncogene; 2018 May 27; 37(18):2379-2393. PubMed ID: 29429991
    [Abstract] [Full Text] [Related]

  • 12. Vascular Smooth Muscle-Specific Progerin Expression Accelerates Atherosclerosis and Death in a Mouse Model of Hutchinson-Gilford Progeria Syndrome.
    Hamczyk MR, Villa-Bellosta R, Gonzalo P, Andrés-Manzano MJ, Nogales P, Bentzon JF, López-Otín C, Andrés V.
    Circulation; 2018 Jul 17; 138(3):266-282. PubMed ID: 29490993
    [Abstract] [Full Text] [Related]

  • 13. Heterochromatin loss as a determinant of progerin-induced DNA damage in Hutchinson-Gilford Progeria.
    Chojnowski A, Ong PF, Foo MXR, Liebl D, Hor LP, Stewart CL, Dreesen O.
    Aging Cell; 2020 Mar 17; 19(3):e13108. PubMed ID: 32087607
    [Abstract] [Full Text] [Related]

  • 14. Transient introduction of human telomerase mRNA improves hallmarks of progeria cells.
    Li Y, Zhou G, Bruno IG, Zhang N, Sho S, Tedone E, Lai TP, Cooke JP, Shay JW.
    Aging Cell; 2019 Aug 17; 18(4):e12979. PubMed ID: 31152494
    [Abstract] [Full Text] [Related]

  • 15. Hutchinson-Gilford progeria syndrome through the lens of transcription.
    Prokocimer M, Barkan R, Gruenbaum Y.
    Aging Cell; 2013 Aug 17; 12(4):533-43. PubMed ID: 23496208
    [Abstract] [Full Text] [Related]

  • 16. Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition.
    Glynn MW, Glover TW.
    Hum Mol Genet; 2005 Oct 15; 14(20):2959-69. PubMed ID: 16126733
    [Abstract] [Full Text] [Related]

  • 17. Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts.
    Eisch V, Lu X, Gabriel D, Djabali K.
    Oncotarget; 2016 Apr 26; 7(17):24700-18. PubMed ID: 27015553
    [Abstract] [Full Text] [Related]

  • 18. Epigenetic involvement in Hutchinson-Gilford progeria syndrome: a mini-review.
    Arancio W, Pizzolanti G, Genovese SI, Pitrone M, Giordano C.
    Gerontology; 2014 Apr 26; 60(3):197-203. PubMed ID: 24603298
    [Abstract] [Full Text] [Related]

  • 19. Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome.
    Capell BC, Erdos MR, Madigan JP, Fiordalisi JJ, Varga R, Conneely KN, Gordon LB, Der CJ, Cox AD, Collins FS.
    Proc Natl Acad Sci U S A; 2005 Sep 06; 102(36):12879-84. PubMed ID: 16129833
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome.
    Aguado J, Sola-Carvajal A, Cancila V, Revêchon G, Ong PF, Jones-Weinert CW, Wallén Arzt E, Lattanzi G, Dreesen O, Tripodo C, Rossiello F, Eriksson M, d'Adda di Fagagna F.
    Nat Commun; 2019 Nov 18; 10(1):4990. PubMed ID: 31740672
    [Abstract] [Full Text] [Related]

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