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418 related items for PubMed ID: 28495456

  • 1. Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells.
    Rädler PD, Wehde BL, Wagner KU.
    Mol Cell Endocrinol; 2017 Aug 15; 451():31-39. PubMed ID: 28495456
    [Abstract] [Full Text] [Related]

  • 2. Constitutive activation of JAK2 in mammary epithelium elevates Stat5 signalling, promotes alveologenesis and resistance to cell death, and contributes to tumourigenesis.
    Caffarel MM, Zaragoza R, Pensa S, Li J, Green AR, Watson CJ.
    Cell Death Differ; 2012 Mar 15; 19(3):511-22. PubMed ID: 21941370
    [Abstract] [Full Text] [Related]

  • 3. Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression.
    Wagner KU, Rui H.
    J Mammary Gland Biol Neoplasia; 2008 Mar 15; 13(1):93-103. PubMed ID: 18228120
    [Abstract] [Full Text] [Related]

  • 4. Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis.
    Schmidt JW, Wehde BL, Sakamoto K, Triplett AA, Anderson SM, Tsichlis PN, Leone G, Wagner KU.
    Mol Cell Biol; 2014 Apr 15; 34(7):1363-77. PubMed ID: 24469394
    [Abstract] [Full Text] [Related]

  • 5. Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1.
    Creamer BA, Sakamoto K, Schmidt JW, Triplett AA, Moriggl R, Wagner KU.
    Mol Cell Biol; 2010 Jun 15; 30(12):2957-70. PubMed ID: 20385773
    [Abstract] [Full Text] [Related]

  • 6. Erythropoietin-induced activation of the JAK2/STAT5, PI3K/Akt, and Ras/ERK pathways promotes malignant cell behavior in a modified breast cancer cell line.
    Shi Z, Hodges VM, Dunlop EA, Percy MJ, Maxwell AP, El-Tanani M, Lappin TR.
    Mol Cancer Res; 2010 Apr 15; 8(4):615-26. PubMed ID: 20353997
    [Abstract] [Full Text] [Related]

  • 7. CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy.
    Mapes J, Li Q, Kannan A, Anandan L, Laws M, Lydon JP, Bagchi IC, Bagchi MK.
    PLoS Genet; 2017 Mar 15; 13(3):e1006654. PubMed ID: 28278176
    [Abstract] [Full Text] [Related]

  • 8. MicroRNA-221 regulates proliferation of bovine mammary gland epithelial cells by targeting the STAT5a and IRS1 genes.
    Jiao BL, Zhang XL, Wang SH, Wang LX, Luo ZX, Zhao HB, Khatib H, Wang X.
    J Dairy Sci; 2019 Jan 15; 102(1):426-435. PubMed ID: 30366615
    [Abstract] [Full Text] [Related]

  • 9. ErbB3 drives mammary epithelial survival and differentiation during pregnancy and lactation.
    Williams MM, Vaught DB, Joly MM, Hicks DJ, Sanchez V, Owens P, Rahman B, Elion DL, Balko JM, Cook RS.
    Breast Cancer Res; 2017 Sep 08; 19(1):105. PubMed ID: 28886748
    [Abstract] [Full Text] [Related]

  • 10. Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer.
    Kim MS, Lee WS, Jeong J, Kim SJ, Jin W.
    Oncotarget; 2015 Nov 24; 6(37):40158-71. PubMed ID: 26515594
    [Abstract] [Full Text] [Related]

  • 11. Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer.
    Furth PA, Nakles RE, Millman S, Diaz-Cruz ES, Cabrera MC.
    Breast Cancer Res; 2011 Oct 12; 13(5):220. PubMed ID: 22018398
    [Abstract] [Full Text] [Related]

  • 12. Akt is required for Stat5 activation and mammary differentiation.
    Chen CC, Boxer RB, Stairs DB, Portocarrero CP, Horton RH, Alvarez JV, Birnbaum MJ, Chodosh LA.
    Breast Cancer Res; 2010 Oct 12; 12(5):R72. PubMed ID: 20849614
    [Abstract] [Full Text] [Related]

  • 13. Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells.
    Aksamitiene E, Achanta S, Kolch W, Kholodenko BN, Hoek JB, Kiyatkin A.
    Cell Signal; 2011 Nov 12; 23(11):1794-805. PubMed ID: 21726627
    [Abstract] [Full Text] [Related]

  • 14. Combined treatment with ruxolitinib and MK-2206 inhibits the JAK2/STAT5 and PI3K/AKT pathways via apoptosis in MDA-MB-231 breast cancer cell line.
    Guvenir Celik E, Eroglu O.
    Mol Biol Rep; 2023 Jan 12; 50(1):319-329. PubMed ID: 36331743
    [Abstract] [Full Text] [Related]

  • 15. Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis.
    Mancini ML, Lien EC, Toker A.
    Oncotarget; 2016 Apr 05; 7(14):17301-13. PubMed ID: 27004402
    [Abstract] [Full Text] [Related]

  • 16. Reactive oxygen species via redox signaling to PI3K/AKT pathway contribute to the malignant growth of 4-hydroxy estradiol-transformed mammary epithelial cells.
    Okoh VO, Felty Q, Parkash J, Poppiti R, Roy D.
    PLoS One; 2013 Apr 05; 8(2):e54206. PubMed ID: 23437041
    [Abstract] [Full Text] [Related]

  • 17. The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development.
    Clarkson RW, Boland MP, Kritikou EA, Lee JM, Freeman TC, Tiffen PG, Watson CJ.
    Mol Endocrinol; 2006 Mar 05; 20(3):675-85. PubMed ID: 16293640
    [Abstract] [Full Text] [Related]

  • 18. Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways.
    Chen CC, Stairs DB, Boxer RB, Belka GK, Horseman ND, Alvarez JV, Chodosh LA.
    Genes Dev; 2012 Oct 01; 26(19):2154-68. PubMed ID: 23028142
    [Abstract] [Full Text] [Related]

  • 19. Activated-PAK4 predicts worse prognosis in breast cancer and promotes tumorigenesis through activation of PI3K/AKT signaling.
    He LF, Xu HW, Chen M, Xian ZR, Wen XF, Chen MN, Du CW, Huang WH, Wu JD, Zhang GJ.
    Oncotarget; 2017 Mar 14; 8(11):17573-17585. PubMed ID: 28407679
    [Abstract] [Full Text] [Related]

  • 20. Essential role for Stat5 in the neurotrophic but not in the neuroprotective effect of erythropoietin.
    Byts N, Samoylenko A, Fasshauer T, Ivanisevic M, Hennighausen L, Ehrenreich H, Sirén AL.
    Cell Death Differ; 2008 Apr 14; 15(4):783-92. PubMed ID: 18259195
    [Abstract] [Full Text] [Related]

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