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Journal Abstract Search

190 related items for PubMed ID: 28496142

  • 1. Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis.
    Su TH, Shiau CW, Jao P, Yang NJ, Tai WT, Liu CJ, Tseng TC, Yang HC, Liu CH, Huang KW, Hu TC, Huang YJ, Wu YM, Chen LJ, Chen PJ, Chen DS, Chen KF, Kao JH.
    Sci Rep; 2017 May 11; 7(1):1728. PubMed ID: 28496142
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  • 3. Discovery of novel Src homology region 2 domain-containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma.
    Tai WT, Shiau CW, Chen PJ, Chu PY, Huang HP, Liu CY, Huang JW, Chen KF.
    Hepatology; 2014 Jan 11; 59(1):190-201. PubMed ID: 23908138
    [Abstract] [Full Text] [Related]

  • 4. Sorafenib analogue SC-60 induces apoptosis through the SHP-1/STAT3 pathway and enhances docetaxel cytotoxicity in triple-negative breast cancer cells.
    Liu CY, Su JC, Huang TT, Chu PY, Huang CT, Wang WL, Lee CH, Lau KY, Tsai WC, Yang HP, Shiau CW, Tseng LM, Chen KF.
    Mol Oncol; 2017 Mar 11; 11(3):266-279. PubMed ID: 28084011
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  • 5. Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells.
    Liu CY, Chen KF, Chao TI, Chu PY, Huang CT, Huang TT, Yang HP, Wang WL, Lee CH, Lau KY, Tsai WC, Su JC, Wu CY, Chen MH, Shiau CW, Tseng LM.
    J Mol Med (Berl); 2017 Sep 11; 95(9):965-975. PubMed ID: 28578456
    [Abstract] [Full Text] [Related]

  • 6. A combination of sorafenib and SC-43 is a synergistic SHP-1 agonist duo to advance hepatocellular carcinoma therapy.
    Chao TI, Tai WT, Hung MH, Tsai MH, Chen MH, Chang MJ, Shiau CW, Chen KF.
    Cancer Lett; 2016 Feb 28; 371(2):205-13. PubMed ID: 26679051
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  • 7. Signal transducer and activator of transcription 3 as molecular therapy for non-small-cell lung cancer.
    Wang CY, Chao TT, Tai WT, Chang FY, Su WP, Chen YL, Chen PT, Weng CY, Yuan A, Shiau CW, Yu CJ, Chen KF.
    J Thorac Oncol; 2014 Apr 28; 9(4):488-96. PubMed ID: 24736071
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  • 9. A sorafenib derivative and novel SHP-1 agonist, SC-59, acts synergistically with radiotherapy in hepatocellular carcinoma cells through inhibition of STAT3.
    Huang CY, Tai WT, Hsieh CY, Hsu WM, Lai YJ, Chen LJ, Shiau CW, Chen KF.
    Cancer Lett; 2014 Jul 28; 349(2):136-43. PubMed ID: 24735751
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  • 10. Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma.
    Tai WT, Cheng AL, Shiau CW, Huang HP, Huang JW, Chen PJ, Chen KF.
    J Hepatol; 2011 Nov 28; 55(5):1041-8. PubMed ID: 21354226
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  • 14. SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma.
    Su JC, Tseng PH, Wu SH, Hsu CY, Tai WT, Li YS, Chen IT, Liu CY, Chen KF, Shiau CW.
    Neoplasia; 2014 Jul 28; 16(7):595-605. PubMed ID: 25047655
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib.
    Liu Y, Wang Z, Kwong SQ, Lui ELH, Friedman SL, Li FR, Lam RWC, Zhang GC, Zhang H, Ye T.
    J Hepatol; 2011 Sep 28; 55(3):612-625. PubMed ID: 21251937
    [Abstract] [Full Text] [Related]

  • 16. New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis.
    Wang Y, Gao J, Zhang D, Zhang J, Ma J, Jiang H.
    J Hepatol; 2010 Jul 28; 53(1):132-44. PubMed ID: 20447716
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  • 17. Rilpivirine attenuates liver fibrosis through selective STAT1-mediated apoptosis in hepatic stellate cells.
    Martí-Rodrigo A, Alegre F, Moragrega ÁB, García-García F, Martí-Rodrigo P, Fernández-Iglesias A, Gracia-Sancho J, Apostolova N, Esplugues JV, Blas-García A.
    Gut; 2020 May 28; 69(5):920-932. PubMed ID: 31530714
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  • 19. Obatoclax analog SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells.
    Liu CY, Su JC, Ni MH, Tseng LM, Chu PY, Wang DS, Tai WT, Kao YP, Hung MH, Shiau CW, Chen KF.
    Breast Cancer Res Treat; 2014 Jul 28; 146(1):71-84. PubMed ID: 24903225
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  • 20. A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells.
    Teratani T, Tomita K, Suzuki T, Oshikawa T, Yokoyama H, Shimamura K, Tominaga S, Hiroi S, Irie R, Okada Y, Kurihara C, Ebinuma H, Saito H, Hokari R, Sugiyama K, Kanai T, Miura S, Hibi T.
    Gastroenterology; 2012 Jan 28; 142(1):152-164.e10. PubMed ID: 21995947
    [Abstract] [Full Text] [Related]

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