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310 related items for PubMed ID: 28526414
1. A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53. Ghosh A, Sengupta A, Seerapu GPK, Nakhi A, Shivaji Ramarao EVV, Bung N, Bulusu G, Pal M, Haldar D. Biochem Biophys Res Commun; 2017 Jul 01; 488(3):562-569. PubMed ID: 28526414 [Abstract] [Full Text] [Related]
2. The sirtuin inhibitor tenovin-6 upregulates death receptor 5 and enhances cytotoxic effects of 5-fluorouracil and oxaliplatin in colon cancer cells. Ueno T, Endo S, Saito R, Hirose M, Hirai S, Suzuki H, Yamato K, Hyodo I. Oncol Res; 2013 Jul 01; 21(3):155-64. PubMed ID: 24512730 [Abstract] [Full Text] [Related]
3. Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo. Zopf S, Neureiter D, Bouralexis S, Abt T, Glaser KB, Okamoto K, Ganslmayer M, Hahn EG, Herold C, Ocker M. Int J Oncol; 2007 Dec 01; 31(6):1391-402. PubMed ID: 17982666 [Abstract] [Full Text] [Related]
4. Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy. Wang S, El-Deiry WS. Proc Natl Acad Sci U S A; 2003 Dec 09; 100(25):15095-100. PubMed ID: 14645705 [Abstract] [Full Text] [Related]
5. Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis. Puca R, Nardinocchi L, Starace G, Rechavi G, Sacchi A, Givol D, D'Orazi G. Free Radic Biol Med; 2010 May 15; 48(10):1338-46. PubMed ID: 20171273 [Abstract] [Full Text] [Related]
6. SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2. Peck B, Chen CY, Ho KK, Di Fruscia P, Myatt SS, Coombes RC, Fuchter MJ, Hsiao CD, Lam EW. Mol Cancer Ther; 2010 Apr 15; 9(4):844-55. PubMed ID: 20371709 [Abstract] [Full Text] [Related]
7. Kaempferol induces apoptosis in human HCT116 colon cancer cells via the Ataxia-Telangiectasia Mutated-p53 pathway with the involvement of p53 Upregulated Modulator of Apoptosis. Li W, Du B, Wang T, Wang S, Zhang J. Chem Biol Interact; 2009 Jan 27; 177(2):121-7. PubMed ID: 19028473 [Abstract] [Full Text] [Related]
8. Metformin induces microRNA-34a to downregulate the Sirt1/Pgc-1α/Nrf2 pathway, leading to increased susceptibility of wild-type p53 cancer cells to oxidative stress and therapeutic agents. Do MT, Kim HG, Choi JH, Jeong HG. Free Radic Biol Med; 2014 Sep 27; 74():21-34. PubMed ID: 24970682 [Abstract] [Full Text] [Related]
9. The p53 stabilizing compound CP-31398 induces apoptosis by activating the intrinsic Bax/mitochondrial/caspase-9 pathway. Luu Y, Bush J, Cheung KJ, Li G. Exp Cell Res; 2002 Jun 10; 276(2):214-22. PubMed ID: 12027451 [Abstract] [Full Text] [Related]
10. SIRT1 activation by resveratrol ameliorates cisplatin-induced renal injury through deacetylation of p53. Kim DH, Jung YJ, Lee JE, Lee AS, Kang KP, Lee S, Park SK, Han MK, Lee SY, Ramkumar KM, Sung MJ, Kim W. Am J Physiol Renal Physiol; 2011 Aug 10; 301(2):F427-35. PubMed ID: 21593185 [Abstract] [Full Text] [Related]
11. Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21. El-Khatib M, Geara F, Haddadin MJ, Gali-Muhtasib H. Radiat Oncol; 2010 Nov 15; 5():107. PubMed ID: 21078189 [Abstract] [Full Text] [Related]
12. Sirt1 attenuates camptothecin-induced apoptosis through caspase-3 pathway in porcine preadipocytes. Pang WJ, Xiong Y, Wang Y, Tong Q, Yang GS. Exp Cell Res; 2013 Mar 10; 319(5):670-83. PubMed ID: 23313858 [Abstract] [Full Text] [Related]
13. Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1. Lee WY, Lee WT, Cheng CH, Chen KC, Chou CM, Chung CH, Sun MS, Cheng HW, Ho MN, Lin CW. Oncotarget; 2015 Sep 29; 6(29):27580-95. PubMed ID: 26363315 [Abstract] [Full Text] [Related]
14. Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Heltweg B, Gatbonton T, Schuler AD, Posakony J, Li H, Goehle S, Kollipara R, Depinho RA, Gu Y, Simon JA, Bedalov A. Cancer Res; 2006 Apr 15; 66(8):4368-77. PubMed ID: 16618762 [Abstract] [Full Text] [Related]
15. Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin. Lim DY, Park JH. Am J Physiol Gastrointest Liver Physiol; 2009 May 15; 296(5):G1060-8. PubMed ID: 19264955 [Abstract] [Full Text] [Related]
16. SIRT1 is upregulated in cutaneous T-cell lymphoma, and its inhibition induces growth arrest and apoptosis. Nihal M, Ahmad N, Wood GS. Cell Cycle; 2014 May 15; 13(4):632-40. PubMed ID: 24343700 [Abstract] [Full Text] [Related]
17. Javamide-I-O-methyl ester increases p53 acetylation and induces cell death via activating caspase 3/7 in monocytic THP-1 cells. Park JB. Phytomedicine; 2016 Dec 01; 23(13):1647-1652. PubMed ID: 27823629 [Abstract] [Full Text] [Related]
18. Tenovin-6-mediated inhibition of SIRT1/2 induces apoptosis in acute lymphoblastic leukemia (ALL) cells and eliminates ALL stem/progenitor cells. Jin Y, Cao Q, Chen C, Du X, Jin B, Pan J. BMC Cancer; 2015 Apr 07; 15():226. PubMed ID: 25884180 [Abstract] [Full Text] [Related]
19. Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival. Ford J, Jiang M, Milner J. Cancer Res; 2005 Nov 15; 65(22):10457-63. PubMed ID: 16288037 [Abstract] [Full Text] [Related]
20. Icariin reduces human colon carcinoma cell growth and metastasis by enhancing p53 activities. Tian M, Yang S, Yan X. Braz J Med Biol Res; 2018 Aug 06; 51(10):e7151. PubMed ID: 30088538 [Abstract] [Full Text] [Related] Page: [Next] [New Search]