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338 related items for PubMed ID: 28545543

  • 21. Sphingolipid metabolism governs Purkinje cell patterned degeneration in Atxn1[82Q]/+ mice.
    Blot FGC, Krijnen WHJJ, Den Hoedt S, Osório C, White JJ, Mulder MT, Schonewille M.
    Proc Natl Acad Sci U S A; 2021 Sep 07; 118(36):. PubMed ID: 34479994
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  • 22. Mesenchymal stem cells attenuate peripheral neuronal degeneration in spinocerebellar ataxia type 1 knockin mice.
    Mieda T, Suto N, Iizuka A, Matsuura S, Iizuka H, Takagishi K, Nakamura K, Hirai H.
    J Neurosci Res; 2016 Mar 07; 94(3):246-52. PubMed ID: 26707550
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  • 23. Focused cerebellar laser light induced hyperthermia improves symptoms and pathology of polyglutamine disease SCA1 in a mouse model.
    Hearst SM, Shao Q, Lopez M, Raucher D, Vig PJ.
    Cerebellum; 2014 Oct 07; 13(5):596-606. PubMed ID: 24930030
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  • 24. Cerebellar Transcriptome Profiles of ATXN1 Transgenic Mice Reveal SCA1 Disease Progression and Protection Pathways.
    Ingram M, Wozniak EAL, Duvick L, Yang R, Bergmann P, Carson R, O'Callaghan B, Zoghbi HY, Henzler C, Orr HT.
    Neuron; 2016 Mar 16; 89(6):1194-1207. PubMed ID: 26948890
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  • 25. Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.
    Crespo-Barreto J, Fryer JD, Shaw CA, Orr HT, Zoghbi HY.
    PLoS Genet; 2010 Jul 08; 6(7):e1001021. PubMed ID: 20628574
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  • 26. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
    Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajić A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT.
    Neuron; 2018 Mar 21; 97(6):1235-1243.e5. PubMed ID: 29526553
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  • 27. Glial S100B protein modulates mutant ataxin-1 aggregation and toxicity: TRTK12 peptide, a potential candidate for SCA1 therapy.
    Vig PJ, Hearst S, Shao Q, Lopez ME, Murphy HA, Safaya E.
    Cerebellum; 2011 Jun 21; 10(2):254-66. PubMed ID: 21384195
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  • 28. Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model.
    Watase K, Gatchel JR, Sun Y, Emamian E, Atkinson R, Richman R, Mizusawa H, Orr HT, Shaw C, Zoghbi HY.
    PLoS Med; 2007 May 21; 4(5):e182. PubMed ID: 17535104
    [Abstract] [Full Text] [Related]

  • 29. Altered calcium signaling in Bergmann glia contributes to spinocerebellar ataxia type-1 in a mouse model of SCA1.
    Nanclares C, Noriega-Prieto JA, Labrada-Moncada FE, Cvetanovic M, Araque A, Kofuji P.
    Neurobiol Dis; 2023 Oct 15; 187():106318. PubMed ID: 37802154
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  • 30. The extra-cerebellar effects of spinocerebellar ataxia type 1 (SCA1): looking beyond the cerebellum.
    Olmos V, Gogia N, Luttik K, Haidery F, Lim J.
    Cell Mol Life Sci; 2022 Jul 08; 79(8):404. PubMed ID: 35802260
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  • 31. Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles.
    Handler HP, Duvick L, Mitchell JS, Cvetanovic M, Reighard M, Soles A, Mather KB, Rainwater O, Serres S, Nichols-Meade T, Coffin SL, You Y, Ruis BL, O'Callaghan B, Henzler C, Zoghbi HY, Orr HT.
    Neuron; 2023 Feb 15; 111(4):493-507.e6. PubMed ID: 36577403
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  • 32. BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1.
    Ding Y, Adachi H, Katsuno M, Sahashi K, Kondo N, Iida M, Tohnai G, Nakatsuji H, Sobue G.
    Neuroscience; 2016 Jul 07; 327():20-31. PubMed ID: 27058144
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  • 33. Recovery from polyglutamine-induced neurodegeneration in conditional SCA1 transgenic mice.
    Zu T, Duvick LA, Kaytor MD, Berlinger MS, Zoghbi HY, Clark HB, Orr HT.
    J Neurosci; 2004 Oct 06; 24(40):8853-61. PubMed ID: 15470152
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  • 34. Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration.
    Furrer SA, Mohanachandran MS, Waldherr SM, Chang C, Damian VA, Sopher BL, Garden GA, La Spada AR.
    J Neurosci; 2011 Nov 09; 31(45):16269-78. PubMed ID: 22072678
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  • 35. Neuronal Atrophy Early in Degenerative Ataxia Is a Compensatory Mechanism to Regulate Membrane Excitability.
    Dell'Orco JM, Wasserman AH, Chopra R, Ingram MA, Hu YS, Singh V, Wulff H, Opal P, Orr HT, Shakkottai VG.
    J Neurosci; 2015 Aug 12; 35(32):11292-307. PubMed ID: 26269637
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  • 36. Cerebellar contribution to cognitive deficits and prefrontal cortex dysfunction in Spinocerebellar Ataxia Type 1 (SCA1).
    Sbrocco K, Borgenheimer E, Zhang Y, Koob M, Cvetanovic M.
    bioRxiv; 2024 Jul 10. PubMed ID: 39026827
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  • 37. Knockdown of acid-sensing ion channel 1a (ASIC1a) suppresses disease phenotype in SCA1 mouse model.
    Vig PJ, Hearst SM, Shao Q, Lopez ME.
    Cerebellum; 2014 Aug 10; 13(4):479-90. PubMed ID: 24788087
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  • 38. Therapeutic Strategies for Spinocerebellar Ataxia Type 1.
    Kerkhof LMC, van de Warrenburg BPC, van Roon-Mom WMC, Buijsen RAM.
    Biomolecules; 2023 May 02; 13(5):. PubMed ID: 37238658
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  • 39. Partial loss of Tip60 slows mid-stage neurodegeneration in a spinocerebellar ataxia type 1 (SCA1) mouse model.
    Gehrking KM, Andresen JM, Duvick L, Lough J, Zoghbi HY, Orr HT.
    Hum Mol Genet; 2011 Jun 01; 20(11):2204-12. PubMed ID: 21427130
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  • 40. Genetic Modeling of the Neurodegenerative Disease Spinocerebellar Ataxia Type 1 in Zebrafish.
    Elsaey MA, Namikawa K, Köster RW.
    Int J Mol Sci; 2021 Jul 08; 22(14):. PubMed ID: 34298970
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