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Journal Abstract Search

294 related items for PubMed ID: 28570076

  • 1. Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression.
    Kaiser CE, Van Ert NA, Agrawal P, Chawla R, Yang D, Hurley LH.
    J Am Chem Soc; 2017 Jun 28; 139(25):8522-8536. PubMed ID: 28570076
    [Abstract] [Full Text] [Related]

  • 2. High-resolution three-dimensional NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation.
    Kerkour A, Marquevielle J, Ivashchenko S, Yatsunyk LA, Mergny JL, Salgado GF.
    J Biol Chem; 2017 May 12; 292(19):8082-8091. PubMed ID: 28330874
    [Abstract] [Full Text] [Related]

  • 3. G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.
    Cogoi S, Xodo LE.
    Nucleic Acids Res; 2006 May 12; 34(9):2536-49. PubMed ID: 16687659
    [Abstract] [Full Text] [Related]

  • 4. KRAS promoter oligonucleotide with decoy activity dimerizes into a unique topology consisting of two G-quadruplex units.
    Podbevšek P, Plavec J.
    Nucleic Acids Res; 2016 Jan 29; 44(2):917-25. PubMed ID: 26656490
    [Abstract] [Full Text] [Related]

  • 5. Identification and characterization of a new G-quadruplex forming region within the kRAS promoter as a transcriptional regulator.
    Morgan RK, Batra H, Gaerig VC, Hockings J, Brooks TA.
    Biochim Biophys Acta; 2016 Feb 29; 1859(2):235-45. PubMed ID: 26597160
    [Abstract] [Full Text] [Related]

  • 6. Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins.
    Cogoi S, Paramasivam M, Spolaore B, Xodo LE.
    Nucleic Acids Res; 2008 Jun 29; 36(11):3765-80. PubMed ID: 18490377
    [Abstract] [Full Text] [Related]

  • 7. Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription.
    Paramasivam M, Membrino A, Cogoi S, Fukuda H, Nakagama H, Xodo LE.
    Nucleic Acids Res; 2009 May 29; 37(9):2841-53. PubMed ID: 19282454
    [Abstract] [Full Text] [Related]

  • 8. Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA.
    Cogoi S, Rapozzi V, Cauci S, Xodo LE.
    Biochim Biophys Acta Gen Subj; 2017 May 29; 1861(5 Pt B):1389-1398. PubMed ID: 27888145
    [Abstract] [Full Text] [Related]

  • 9. Protein hnRNPA1 binds to a critical G-rich element of KRAS and unwinds G-quadruplex structures: implications in transcription.
    Xodo L, Paramasivam M, Membrino A, Cogoi S.
    Nucleic Acids Symp Ser (Oxf); 2008 May 29; (52):159-60. PubMed ID: 18776302
    [Abstract] [Full Text] [Related]

  • 10. The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element.
    Cogoi S, Paramasivam M, Membrino A, Yokoyama KK, Xodo LE.
    J Biol Chem; 2010 Jul 16; 285(29):22003-16. PubMed ID: 20457603
    [Abstract] [Full Text] [Related]

  • 11. 1H, 13C, and 15N chemical shift assignments of a G-quadruplex forming sequence within the KRAS proto-oncogene promoter region.
    Marquevielle J, Kumar MVV, Mergny JL, Salgado GF.
    Biomol NMR Assign; 2018 Apr 16; 12(1):123-127. PubMed ID: 29189986
    [Abstract] [Full Text] [Related]

  • 12. The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription.
    Cogoi S, Ferino A, Miglietta G, Pedersen EB, Xodo LE.
    Nucleic Acids Res; 2018 Jan 25; 46(2):661-676. PubMed ID: 29165690
    [Abstract] [Full Text] [Related]

  • 13. Structure of two G-quadruplexes in equilibrium in the KRAS promoter.
    Marquevielle J, Robert C, Lagrabette O, Wahid M, Bourdoncle A, Xodo LE, Mergny JL, Salgado GF.
    Nucleic Acids Res; 2020 Sep 18; 48(16):9336-9345. PubMed ID: 32432667
    [Abstract] [Full Text] [Related]

  • 14. The Consequences of Overlapping G-Quadruplexes and i-Motifs in the Platelet-Derived Growth Factor Receptor β Core Promoter Nuclease Hypersensitive Element Can Explain the Unexpected Effects of Mutations and Provide Opportunities for Selective Targeting of Both Structures by Small Molecules To Downregulate Gene Expression.
    Brown RV, Wang T, Chappeta VR, Wu G, Onel B, Chawla R, Quijada H, Camp SM, Chiang ET, Lassiter QR, Lee C, Phanse S, Turnidge MA, Zhao P, Garcia JGN, Gokhale V, Yang D, Hurley LH.
    J Am Chem Soc; 2017 Jun 07; 139(22):7456-7475. PubMed ID: 28471683
    [Abstract] [Full Text] [Related]

  • 15. DNA G-Quadruplex in Human Telomeres and Oncogene Promoters: Structures, Functions, and Small Molecule Targeting.
    Chen L, Dickerhoff J, Sakai S, Yang D.
    Acc Chem Res; 2022 Sep 20; 55(18):2628-2646. PubMed ID: 36054116
    [Abstract] [Full Text] [Related]

  • 16. Role of Hairpin-Quadruplex DNA Secondary Structural Conversion in the Promoter of hnRNP K in Gene Transcriptional Regulation.
    Qiu J, Liu J, Chen S, Ou TM, Tan JH, Gu LQ, Huang ZS, Li D.
    Org Lett; 2015 Sep 18; 17(18):4584-7. PubMed ID: 26332732
    [Abstract] [Full Text] [Related]

  • 17. KRAS Promoter G-Quadruplexes from Sequences of Different Length: A Physicochemical Study.
    D'Aria F, Pagano B, Petraccone L, Giancola C.
    Int J Mol Sci; 2021 Jan 05; 22(1):. PubMed ID: 33466280
    [Abstract] [Full Text] [Related]

  • 18. Spectroscopic investigation of the interaction between G-quadruplex of KRAS promoter sequence and three isoquinoline alkaloids.
    Wen LN, Xie MX.
    Spectrochim Acta A Mol Biomol Spectrosc; 2017 Jan 15; 171():287-296. PubMed ID: 27565766
    [Abstract] [Full Text] [Related]

  • 19. The 3'-end region of the human PDGFR-β core promoter nuclease hypersensitive element forms a mixture of two unique end-insertion G-quadruplexes.
    Onel B, Carver M, Agrawal P, Hurley LH, Yang D.
    Biochim Biophys Acta Gen Subj; 2018 Apr 15; 1862(4):846-854. PubMed ID: 29288770
    [Abstract] [Full Text] [Related]

  • 20. Role of Poly [ADP-ribose] Polymerase 1 in Activating the Kirsten ras (KRAS) Gene in Response to Oxidative Stress.
    Cinque G, Ferino A, Pedersen EB, Xodo LE.
    Int J Mol Sci; 2020 Aug 28; 21(17):. PubMed ID: 32872305
    [Abstract] [Full Text] [Related]

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