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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

211 related items for PubMed ID: 28571972

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  • 2. In vitro and in vivo antitumor activities of T-3764518, a novel and orally available small molecule stearoyl-CoA desaturase 1 inhibitor.
    Nishizawa S, Sumi H, Satoh Y, Yamamoto Y, Kitazawa S, Honda K, Araki H, Kakoi K, Imamura K, Sasaki M, Miyahisa I, Satomi Y, Nishigaki R, Hirayama M, Aoyama K, Maezaki H, Hara T.
    Eur J Pharmacol; 2017 Jul 15; 807():21-31. PubMed ID: 28442322
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  • 4. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438).
    Léger S, Black WC, Deschenes D, Dolman S, Falgueyret JP, Gagnon M, Guiral S, Huang Z, Guay J, Leblanc Y, Li CS, Massé F, Oballa R, Zhang L.
    Bioorg Med Chem Lett; 2010 Jan 15; 20(2):499-502. PubMed ID: 20004097
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  • 6. Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors.
    Liu G, Lynch JK, Freeman J, Liu B, Xin Z, Zhao H, Serby MD, Kym PR, Suhar TS, Smith HT, Cao N, Yang R, Janis RS, Krauser JA, Cepa SP, Beno DW, Sham HL, Collins CA, Surowy TK, Camp HS.
    J Med Chem; 2007 Jun 28; 50(13):3086-100. PubMed ID: 17530838
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  • 7. 4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable Stearoyl-CoA desaturase-1 (SCD1) inhibitors. Part 1: urea-based analogs.
    Yang SM, Tang Y, Zhang R, Lu H, Kuo GH, Gaul MD, Li Y, Ho G, Conway JG, Liang Y, Lenhard JM, Demarest KT, Murray WV.
    Bioorg Med Chem Lett; 2013 Dec 15; 23(24):6773-6. PubMed ID: 24153205
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  • 8. Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1).
    Deng Y, Yang Z, Shipps GW, Lo SM, West R, Hwa J, Zheng S, Farley C, Lachowicz J, van Heek M, Bass AS, Sinha DP, Mahon CR, Cartwright ME.
    Bioorg Med Chem Lett; 2013 Feb 01; 23(3):791-6. PubMed ID: 23265904
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  • 12. Synthesis and evaluation of novel stearoyl-CoA desaturase 1 inhibitors: 1'-{6-[5-(pyridin-3-ylmethyl)-1,3,4-oxadiazol-2-yl]pyridazin-3-yl}-3,4-dihydrospiro[chromene-2,4'-piperidine] analogs.
    Uto Y, Ueno Y, Kiyotsuka Y, Miyazawa Y, Kurata H, Ogata T, Yamada M, Deguchi T, Konishi M, Takagi T, Wakimoto S, Ohsumi J.
    Eur J Med Chem; 2010 Nov 01; 45(11):4788-96. PubMed ID: 20801551
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  • 18. Biological activity and preclinical efficacy of azetidinyl pyridazines as potent systemically-distributed stearoyl-CoA desaturase inhibitors.
    Isabel E, Powell DA, Black WC, Chan CC, Crane S, Gordon R, Guay J, Guiral S, Huang Z, Robichaud J, Skorey K, Tawa P, Xu L, Zhang L, Oballa R.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):479-83. PubMed ID: 21074991
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  • 20. Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesity.
    Iida T, Ubukata M, Mitani I, Nakagawa Y, Maeda K, Imai H, Ogoshi Y, Hotta T, Sakata S, Sano R, Morinaga H, Negoro T, Oshida S, Tanaka M, Inaba T.
    Eur J Med Chem; 2018 Oct 05; 158():832-852. PubMed ID: 30248655
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