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666 related items for PubMed ID: 28583670

  • 1. Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity.
    Li D, Du Y, Yuan X, Han X, Dong Z, Chen X, Wu H, Zhang J, Xu L, Han C, Zhang M, Xia Q.
    Free Radic Biol Med; 2017 Sep; 110():102-116. PubMed ID: 28583670
    [Abstract] [Full Text] [Related]

  • 2. FGF21 mediates the protective effect of fenofibrate against acetaminophen -induced hepatotoxicity via activating autophagy in mice.
    Zhang Y, Pan Y, Xiong R, Zheng J, Li Q, Zhang S, Li X, Pan X, Yang S.
    Biochem Biophys Res Commun; 2018 Sep 05; 503(2):474-481. PubMed ID: 29730296
    [Abstract] [Full Text] [Related]

  • 3. The role of hypoxia-inducible factor-1α in acetaminophen hepatotoxicity.
    Sparkenbaugh EM, Saini Y, Greenwood KK, LaPres JJ, Luyendyk JP, Copple BL, Maddox JF, Ganey PE, Roth RA.
    J Pharmacol Exp Ther; 2011 Aug 05; 338(2):492-502. PubMed ID: 21576378
    [Abstract] [Full Text] [Related]

  • 4. Hypoxia-Inducible Factor-2α Reprograms Liver Macrophages to Protect Against Acute Liver Injury Through the Production of Interleukin-6.
    Gao RY, Wang M, Liu Q, Feng D, Wen Y, Xia Y, Colgan SP, Eltzschig HK, Ju C.
    Hepatology; 2020 Jun 05; 71(6):2105-2117. PubMed ID: 31529728
    [Abstract] [Full Text] [Related]

  • 5. Hypoxia exacerbates nonalcoholic fatty liver disease via the HIF-2α/PPARα pathway.
    Chen J, Chen J, Fu H, Li Y, Wang L, Luo S, Lu H.
    Am J Physiol Endocrinol Metab; 2019 Oct 01; 317(4):E710-E722. PubMed ID: 31430204
    [Abstract] [Full Text] [Related]

  • 6. Allyl methyl trisulfide protected against acetaminophen (paracetamol)-induced hepatotoxicity by suppressing CYP2E1 and activating Nrf2 in mouse liver.
    Zhao HJ, Li MJ, Zhang MP, Wei MK, Shen LP, Jiang M, Zeng T.
    Food Funct; 2019 Apr 01; 10(4):2244-2253. PubMed ID: 30958500
    [Abstract] [Full Text] [Related]

  • 7. Serotonin deficiency exacerbates acetaminophen-induced liver toxicity in mice.
    Zhang J, Song S, Pang Q, Zhang R, Zhou L, Liu S, Meng F, Wu Q, Liu C.
    Sci Rep; 2015 Jan 29; 5():8098. PubMed ID: 25631548
    [Abstract] [Full Text] [Related]

  • 8. Tetrahydrocurcumin and octahydrocurcumin, the primary and final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: Role of CYP2E1 and Keap1-Nrf2 pathway.
    Luo DD, Chen JF, Liu JJ, Xie JH, Zhang ZB, Gu JY, Zhuo JY, Huang S, Su ZR, Sun ZH.
    Food Chem Toxicol; 2019 Jan 29; 123():349-362. PubMed ID: 30423402
    [Abstract] [Full Text] [Related]

  • 9. Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice.
    Ye D, Wang Y, Li H, Jia W, Man K, Lo CM, Wang Y, Lam KS, Xu A.
    Hepatology; 2014 Sep 29; 60(3):977-89. PubMed ID: 24590984
    [Abstract] [Full Text] [Related]

  • 10. Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia.
    Chaudhuri S, McCullough SS, Hennings L, Letzig L, Simpson PM, Hinson JA, James LP.
    Toxicol Appl Pharmacol; 2011 May 01; 252(3):211-20. PubMed ID: 21316383
    [Abstract] [Full Text] [Related]

  • 11. Effect of trifluoperazine on toxicity, HIF-1α induction and hepatocyte regeneration in acetaminophen toxicity in mice.
    Chaudhuri S, McCullough SS, Hennings L, Brown AT, Li SH, Simpson PM, Hinson JA, James LP.
    Toxicol Appl Pharmacol; 2012 Oct 15; 264(2):192-201. PubMed ID: 22902588
    [Abstract] [Full Text] [Related]

  • 12. Deciphering Acetaminophen-Induced Hepatotoxicity: The Crucial Role of Transcription Factors like Nuclear Factor Erythroid 2-Related Factor 2 as Genetic Determinants of Susceptibility to Drug-Induced Liver Injury.
    Laddha AP, Wu H, Manautou JE.
    Drug Metab Dispos; 2024 Jul 16; 52(8):740-753. PubMed ID: 38857948
    [Abstract] [Full Text] [Related]

  • 13. Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
    Ning C, Gao X, Wang C, Kong Y, Liu Z, Sun H, Sun P, Huo X, Ma X, Meng Q, Liu K.
    Regul Toxicol Pharmacol; 2018 Oct 16; 98():58-68. PubMed ID: 30030101
    [Abstract] [Full Text] [Related]

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  • 15. Immature mice are more susceptible than adult mice to acetaminophen-induced acute liver injury.
    Lu Y, Zhang C, Chen YH, Wang H, Zhang ZH, Chen X, Xu DX.
    Sci Rep; 2017 Feb 16; 7():42736. PubMed ID: 28205631
    [Abstract] [Full Text] [Related]

  • 16. CXCL16 deficiency attenuates acetaminophen-induced hepatotoxicity through decreasing hepatic oxidative stress and inflammation in mice.
    Wang H, Shao Y, Zhang S, Xie A, Ye Y, Shi L, Jin L, Pan X, Lin Z, Li X, Yang S.
    Acta Biochim Biophys Sin (Shanghai); 2017 Jun 01; 49(6):541-549. PubMed ID: 28459937
    [Abstract] [Full Text] [Related]

  • 17. Protection afforded by pre- or post-treatment with 4-phenylbutyrate against liver injury induced by acetaminophen overdose in mice.
    Shimizu D, Ishitsuka Y, Miyata K, Tomishima Y, Kondo Y, Irikura M, Iwawaki T, Oike Y, Irie T.
    Pharmacol Res; 2014 Sep 01; 87():26-41. PubMed ID: 24951965
    [Abstract] [Full Text] [Related]

  • 18. Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation.
    Jiang Y, Fan X, Wang Y, Tan H, Chen P, Zeng H, Huang M, Bi H.
    Chem Biol Interact; 2015 Apr 25; 231():83-9. PubMed ID: 25753323
    [Abstract] [Full Text] [Related]

  • 19. Upregulation of Nrf2-related cytoprotective genes expression by acetaminophen-induced acute hepatotoxicity in mice and the protective role of betaine.
    Khodayar MJ, Kalantari H, Khorsandi L, Rashno M, Zeidooni L.
    Hum Exp Toxicol; 2020 Jul 25; 39(7):948-959. PubMed ID: 32081044
    [Abstract] [Full Text] [Related]

  • 20. Metabolic modulation of acetaminophen-induced hepatotoxicity by osteopontin.
    Wen Y, Wang C, Gu J, Yu C, Wang K, Sun X, Sun Y, Wu H, Tong Y, Xia Q, Kong X.
    Cell Mol Immunol; 2019 May 25; 16(5):483-494. PubMed ID: 29735980
    [Abstract] [Full Text] [Related]

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