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Journal Abstract Search

263 related items for PubMed ID: 28583846

  • 1. Epigenetic effects of inhibition of heat shock protein 90 (HSP90) in human pancreatic and colon cancer.
    Nagaraju GP, Wu C, Merchant N, Chen Z, Lesinski GB, El-Rayes BF.
    Cancer Lett; 2017 Aug 28; 402():110-116. PubMed ID: 28583846
    [Abstract] [Full Text] [Related]

  • 2. Targeting the Janus-activated kinase-2-STAT3 signalling pathway in pancreatic cancer using the HSP90 inhibitor ganetespib.
    Nagaraju GP, Mezina A, Shaib WL, Landry J, El-Rayes BF.
    Eur J Cancer; 2016 Jan 28; 52():109-19. PubMed ID: 26682870
    [Abstract] [Full Text] [Related]

  • 3. Novel synthetic curcumin analogues EF31 and UBS109 are potent DNA hypomethylating agents in pancreatic cancer.
    Nagaraju GP, Zhu S, Wen J, Farris AB, Adsay VN, Diaz R, Snyder JP, Mamoru S, El-Rayes BF.
    Cancer Lett; 2013 Dec 01; 341(2):195-203. PubMed ID: 23933177
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of HSP90 overcomes resistance to chemotherapy and radiotherapy in pancreatic cancer.
    Nagaraju GP, Zakka KM, Landry JC, Shaib WL, Lesinski GB, El-Rayes BF.
    Int J Cancer; 2019 Sep 15; 145(6):1529-1537. PubMed ID: 30801702
    [Abstract] [Full Text] [Related]

  • 5. Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1α and STAT-3.
    Nagaraju GP, Park W, Wen J, Mahaseth H, Landry J, Farris AB, Willingham F, Sullivan PS, Proia DA, El-Hariry I, Taliaferro-Smith L, Diaz R, El-Rayes BF.
    Angiogenesis; 2013 Oct 15; 16(4):903-17. PubMed ID: 23838996
    [Abstract] [Full Text] [Related]

  • 6. Andrographolide suppresses the malignancy of pancreatic cancer via alleviating DNMT3B-dependent repression of tumor suppressor gene ZNF382.
    Zhuang KR, Chen CF, Chan HY, Wang SE, Lee DH, Chen SC, Shyr BU, Chou YJ, Chen CC, Yuan SH, Chang YI, Lee HT, Fu SL.
    Phytomedicine; 2024 Sep 15; 132():155860. PubMed ID: 38991252
    [Abstract] [Full Text] [Related]

  • 7. DNA methylation status of hMLH1, p16(INK4a), and CDH1 is not associated with mRNA expression levels of DNA methyltransferase and DNA demethylase in gastric carcinomas.
    Oue N, Kuraoka K, Kuniyasu H, Yokozaki H, Wakikawa A, Matsusaki K, Yasui W.
    Oncol Rep; 2001 Sep 15; 8(5):1085-9. PubMed ID: 11496321
    [Abstract] [Full Text] [Related]

  • 8. HSP90 inhibition downregulates thymidylate synthase and sensitizes colorectal cancer cell lines to the effect of 5FU-based chemotherapy.
    Nagaraju GP, Alese OB, Landry J, Diaz R, El-Rayes BF.
    Oncotarget; 2014 Oct 30; 5(20):9980-91. PubMed ID: 25296971
    [Abstract] [Full Text] [Related]

  • 9. Heat shock protein 90 (HSP90) is overexpressed in p16-negative oropharyngeal squamous cell carcinoma, and its inhibition in vitro potentiates the effects of chemoradiation.
    Patel K, Wen J, Magliocca K, Muller S, Liu Y, Chen ZG, Saba N, Diaz R.
    Cancer Chemother Pharmacol; 2014 Nov 30; 74(5):1015-22. PubMed ID: 25205430
    [Abstract] [Full Text] [Related]

  • 10. Involvement of epigenetics and microRNA-29b in the urethane induced inception and establishment of mouse lung tumors.
    Pandey M, Sultana S, Gupta KP.
    Exp Mol Pathol; 2014 Feb 30; 96(1):61-70. PubMed ID: 24361357
    [Abstract] [Full Text] [Related]

  • 11. MicroRNA-148b and microRNA-152 reactivate tumor suppressor genes through suppression of DNA methyltransferase-1 gene in pancreatic cancer cell lines.
    Azizi M, Teimoori-Toolabi L, Arzanani MK, Azadmanesh K, Fard-Esfahani P, Zeinali S.
    Cancer Biol Ther; 2014 Apr 30; 15(4):419-27. PubMed ID: 24448385
    [Abstract] [Full Text] [Related]

  • 12. The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer.
    He S, Smith DL, Sequeira M, Sang J, Bates RC, Proia DA.
    Invest New Drugs; 2014 Aug 30; 32(4):577-86. PubMed ID: 24682747
    [Abstract] [Full Text] [Related]

  • 13. Hinokitiol induces DNA demethylation via DNMT1 and UHRF1 inhibition in colon cancer cells.
    Seo JS, Choi YH, Moon JW, Kim HS, Park SH.
    BMC Cell Biol; 2017 Feb 27; 18(1):14. PubMed ID: 28241740
    [Abstract] [Full Text] [Related]

  • 14. Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition.
    Hackl C, Lang SA, Moser C, Mori A, Fichtner-Feigl S, Hellerbrand C, Dietmeier W, Schlitt HJ, Geissler EK, Stoeltzing O.
    BMC Cancer; 2010 Dec 03; 10():668. PubMed ID: 21129190
    [Abstract] [Full Text] [Related]

  • 15. Targeting heat-shock protein 90 with ganetespib for molecularly targeted therapy of gastric cancer.
    Liu H, Lu J, Hua Y, Zhang P, Liang Z, Ruan L, Lian C, Shi H, Chen K, Tu Z.
    Cell Death Dis; 2015 Jan 15; 6(1):e1595. PubMed ID: 25590805
    [Abstract] [Full Text] [Related]

  • 16. DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer.
    Jin B, Yao B, Li JL, Fields CR, Delmas AL, Liu C, Robertson KD.
    Cancer Res; 2009 Sep 15; 69(18):7412-21. PubMed ID: 19723660
    [Abstract] [Full Text] [Related]

  • 17. Effects of ginsenoside Rg3 on epigenetic modification in ovarian cancer cells.
    Zhao L, Shou H, Chen L, Gao W, Fang C, Zhang P.
    Oncol Rep; 2019 Jun 15; 41(6):3209-3218. PubMed ID: 31002353
    [Abstract] [Full Text] [Related]

  • 18. Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy.
    Ying W, Du Z, Sun L, Foley KP, Proia DA, Blackman RK, Zhou D, Inoue T, Tatsuta N, Sang J, Ye S, Acquaviva J, Ogawa LS, Wada Y, Barsoum J, Koya K.
    Mol Cancer Ther; 2012 Feb 15; 11(2):475-84. PubMed ID: 22144665
    [Abstract] [Full Text] [Related]

  • 19. Targeted inhibition of Hsp90 by ganetespib is effective across a broad spectrum of breast cancer subtypes.
    Friedland JC, Smith DL, Sang J, Acquaviva J, He S, Zhang C, Proia DA.
    Invest New Drugs; 2014 Feb 15; 32(1):14-24. PubMed ID: 23686707
    [Abstract] [Full Text] [Related]

  • 20. miR-124 and miR-506 inhibit colorectal cancer progression by targeting DNMT3B and DNMT1.
    Chen Z, Liu S, Tian L, Wu M, Ai F, Tang W, Zhao L, Ding J, Zhang L, Tang A.
    Oncotarget; 2015 Nov 10; 6(35):38139-50. PubMed ID: 26497367
    [Abstract] [Full Text] [Related]

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