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136 related items for PubMed ID: 28587455

  • 1. Insights on the Interaction between Transthyretin and Aβ in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal.
    Gimeno A, Santos LM, Alemi M, Rivas J, Blasi D, Cotrina EY, Llop J, Valencia G, Cardoso I, Quintana J, Arsequell G, Jiménez-Barbero J.
    J Med Chem; 2017 Jul 13; 60(13):5749-5758. PubMed ID: 28587455
    [Abstract] [Full Text] [Related]

  • 2. Transthyretin stabilization by iododiflunisal promotes amyloid-β peptide clearance, decreases its deposition, and ameliorates cognitive deficits in an Alzheimer's disease mouse model.
    Ribeiro CA, Oliveira SM, Guido LF, Magalhães A, Valencia G, Arsequell G, Saraiva MJ, Cardoso I.
    J Alzheimers Dis; 2014 Jul 13; 39(2):357-70. PubMed ID: 24169237
    [Abstract] [Full Text] [Related]

  • 3. Transthyretin stability is critical in assisting beta amyloid clearance- Relevance of transthyretin stabilization in Alzheimer's disease.
    Alemi M, Silva SC, Santana I, Cardoso I.
    CNS Neurosci Ther; 2017 Jul 13; 23(7):605-619. PubMed ID: 28570028
    [Abstract] [Full Text] [Related]

  • 4. Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, Aβ Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer's Disease Drug Discovery.
    Cotrina EY, Gimeno A, Llop J, Jiménez-Barbero J, Quintana J, Valencia G, Cardoso I, Prohens R, Arsequell G.
    J Med Chem; 2020 Mar 26; 63(6):3205-3214. PubMed ID: 32124607
    [Abstract] [Full Text] [Related]

  • 5. Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD.
    Rios X, Gómez-Vallejo V, Martín A, Cossío U, Morcillo MÁ, Alemi M, Cardoso I, Quintana J, Jiménez-Barbero J, Cotrina EY, Valencia G, Arsequell G, Llop J.
    Sci Rep; 2019 Sep 20; 9(1):13672. PubMed ID: 31541162
    [Abstract] [Full Text] [Related]

  • 6. Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer.
    Cotrina EY, Oliveira Â, Leite JP, Llop J, Gales L, Quintana J, Cardoso I, Arsequell G.
    Int J Mol Sci; 2020 Sep 28; 21(19):. PubMed ID: 32998442
    [Abstract] [Full Text] [Related]

  • 7. Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in vivo Molecular Imaging Study1.
    Rejc L, Gómez-Vallejo V, Rios X, Cossío U, Baz Z, Mujica E, Gião T, Cotrina EY, Jiménez-Barbero J, Quintana J, Arsequell G, Cardoso I, Llop J.
    J Alzheimers Dis; 2020 Sep 28; 77(1):99-112. PubMed ID: 32804152
    [Abstract] [Full Text] [Related]

  • 8. An Assay for Screening Potential Drug Candidates for Alzheimer's Disease That Act as Chaperones of the Transthyretin and Amyloid-β Peptides Interaction.
    Cotrina EY, Gimeno A, Llop J, Jiménez-Barbero J, Quintana J, Prohens R, Cardoso I, Arsequell G.
    Chemistry; 2020 Dec 23; 26(72):17462-17469. PubMed ID: 32761825
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and PET Imaging Biodistribution Studies of Radiolabeled Iododiflunisal, a Transthyretin Tetramer Stabilizer, Candidate Drug for Alzheimer's Disease.
    Joshi SM, Wilson TC, Li Z, Preshlock S, Gómez-Vallejo V, Gouverneur V, Llop J, Arsequell G.
    Molecules; 2024 Jan 18; 29(2):. PubMed ID: 38257401
    [Abstract] [Full Text] [Related]

  • 10. Copper mediated amyloid-β binding to Transthyretin.
    Ciccone L, Fruchart-Gaillard C, Mourier G, Savko M, Nencetti S, Orlandini E, Servent D, Stura EA, Shepard W.
    Sci Rep; 2018 Sep 13; 8(1):13744. PubMed ID: 30213975
    [Abstract] [Full Text] [Related]

  • 11. The inhibition of cellular toxicity of amyloid-β by dissociated transthyretin.
    Cao Q, Anderson DH, Liang WY, Chou J, Saelices L.
    J Biol Chem; 2020 Oct 09; 295(41):14015-14024. PubMed ID: 32769117
    [Abstract] [Full Text] [Related]

  • 12. Stability of the transthyretin molecule as a key factor in the interaction with a-beta peptide--relevance in Alzheimer's disease.
    Ribeiro CA, Saraiva MJ, Cardoso I.
    PLoS One; 2012 Oct 09; 7(9):e45368. PubMed ID: 23028965
    [Abstract] [Full Text] [Related]

  • 13. Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting.
    Plissonneau M, Pansieri J, Heinrich-Balard L, Morfin JF, Stransky-Heilkron N, Rivory P, Mowat P, Dumoulin M, Cohen R, Allémann É, Tόth É, Saraiva MJ, Louis C, Tillement O, Forge V, Lux F, Marquette C.
    J Nanobiotechnology; 2016 Jul 25; 14(1):60. PubMed ID: 27455834
    [Abstract] [Full Text] [Related]

  • 14. Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative.
    Almeida MR, Macedo B, Cardoso I, Alves I, Valencia G, Arsequell G, Planas A, Saraiva MJ.
    Biochem J; 2004 Jul 15; 381(Pt 2):351-6. PubMed ID: 15080795
    [Abstract] [Full Text] [Related]

  • 15. Mechanisms of transthyretin inhibition of β-amyloid aggregation in vitro.
    Li X, Zhang X, Ladiwala AR, Du D, Yadav JK, Tessier PM, Wright PE, Kelly JW, Buxbaum JN.
    J Neurosci; 2013 Dec 11; 33(50):19423-33. PubMed ID: 24336709
    [Abstract] [Full Text] [Related]

  • 16. Human transthyretin in complex with iododiflunisal: structural features associated with a potent amyloid inhibitor.
    Gales L, Macedo-Ribeiro S, Arsequell G, Valencia G, Saraiva MJ, Damas AM.
    Biochem J; 2005 Jun 01; 388(Pt 2):615-21. PubMed ID: 15689188
    [Abstract] [Full Text] [Related]

  • 17. The Function of Transthyretin Complexes with Metallothionein in Alzheimer's Disease.
    Zaręba N, Kepinska M.
    Int J Mol Sci; 2020 Nov 26; 21(23):. PubMed ID: 33256250
    [Abstract] [Full Text] [Related]

  • 18. Transthyretin participates in beta-amyloid transport from the brain to the liver--involvement of the low-density lipoprotein receptor-related protein 1?
    Alemi M, Gaiteiro C, Ribeiro CA, Santos LM, Gomes JR, Oliveira SM, Couraud PO, Weksler B, Romero I, Saraiva MJ, Cardoso I.
    Sci Rep; 2016 Feb 03; 6():20164. PubMed ID: 26837706
    [Abstract] [Full Text] [Related]

  • 19. A Cyclic Peptide Mimic of the β-Amyloid Binding Domain on Transthyretin.
    Cho PY, Joshi G, Boersma MD, Johnson JA, Murphy RM.
    ACS Chem Neurosci; 2015 May 20; 6(5):778-89. PubMed ID: 25713928
    [Abstract] [Full Text] [Related]

  • 20. Characterization of the interaction of β-amyloid with transthyretin monomers and tetramers.
    Du J, Murphy RM.
    Biochemistry; 2010 Sep 28; 49(38):8276-89. PubMed ID: 20795734
    [Abstract] [Full Text] [Related]

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