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Journal Abstract Search

729 related items for PubMed ID: 2860558

  • 1. Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist.
    Leysen JE, Gommeren W, Van Gompel P, Wynants J, Janssen PF, Laduron PM.
    Mol Pharmacol; 1985 Jun; 27(6):600-11. PubMed ID: 2860558
    [Abstract] [Full Text] [Related]

  • 2. In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone.
    Leysen JE, Janssen PM, Gommeren W, Wynants J, Pauwels PJ, Janssen PA.
    Mol Pharmacol; 1992 Mar; 41(3):494-508. PubMed ID: 1372084
    [Abstract] [Full Text] [Related]

  • 3. Down regulation of serotonin-S2 receptor sites in rat brain by chronic treatment with the serotonin-S2 antagonists: ritanserin and setoperone.
    Leysen JE, Van Gompel P, Gommeren W, Woestenborghs R, Janssen PA.
    Psychopharmacology (Berl); 1986 Mar; 88(4):434-44. PubMed ID: 3010361
    [Abstract] [Full Text] [Related]

  • 4. Biochemical profile of risperidone, a new antipsychotic.
    Leysen JE, Gommeren W, Eens A, de Chaffoy de Courcelles D, Stoof JC, Janssen PA.
    J Pharmacol Exp Ther; 1988 Nov; 247(2):661-70. PubMed ID: 2460616
    [Abstract] [Full Text] [Related]

  • 5. Identification of nonserotonergic [3H]ketanserin binding sites associated with nerve terminals in rat brain and with platelets; relation with release of biogenic amine metabolites induced by ketanserin- and tetrabenazine-like drugs.
    Leysen JE, Eens A, Gommeren W, van Gompel P, Wynants J, Janssen PA.
    J Pharmacol Exp Ther; 1988 Jan; 244(1):310-21. PubMed ID: 3336007
    [Abstract] [Full Text] [Related]

  • 6. In vitro and in vivo binding characteristics of a new long-acting histamine H1 antagonist, astemizole.
    Laduron PM, Janssen PF, Gommeren W, Leysen JE.
    Mol Pharmacol; 1982 Mar; 21(2):294-300. PubMed ID: 6124876
    [Abstract] [Full Text] [Related]

  • 7. Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity.
    Leysen JE, Janssen PM, Megens AA, Schotte A.
    J Clin Psychiatry; 1994 May; 55 Suppl():5-12. PubMed ID: 7520908
    [Abstract] [Full Text] [Related]

  • 8. Characterization of solubilized serotonin (S2) receptors in rat brain.
    Ilien B, Gorissen H, Laduron PM.
    Mol Pharmacol; 1982 Sep; 22(2):243-9. PubMed ID: 7144728
    [Abstract] [Full Text] [Related]

  • 9. Autoradiographic localization of 3H-paroxetine-labeled serotonin uptake sites in rat brain.
    De Souza EB, Kuyatt BL.
    Synapse; 1987 Sep; 1(5):488-96. PubMed ID: 2975068
    [Abstract] [Full Text] [Related]

  • 10. Hypothermia reduces the rate of dissociation of specific ligands from dopamine-D2 and 5-hydroxytryptamine1A receptors in the mouse brain in vivo.
    Stenfors C, Ross SB.
    Naunyn Schmiedebergs Arch Pharmacol; 2001 Nov; 364(5):479-86. PubMed ID: 11692232
    [Abstract] [Full Text] [Related]

  • 11. Preclinical evaluation of McN-5707 as a potential antidepressant.
    Shank RP, Gardocki JF, Schneider CR, Vaught JL, Setler PE, Maryanoff BE, McComsey DF.
    J Pharmacol Exp Ther; 1987 Jul; 242(1):74-84. PubMed ID: 3039115
    [Abstract] [Full Text] [Related]

  • 12. [3H]paroxetine binding and serotonin content of rat and rabbit cortical areas, hippocampus, neostriatum, ventral mesencephalic tegmentum, and midbrain raphe nuclei region.
    Dewar KM, Reader TA, Grondin L, Descarries L.
    Synapse; 1991 Sep; 9(1):14-26. PubMed ID: 1724575
    [Abstract] [Full Text] [Related]

  • 13. Pharmacological profile of AD-5423, a novel antipsychotic with both potent dopamine-D2 and serotonin-S2 antagonist properties.
    Oka M, Noda Y, Ochi Y, Furukawa K, Une T, Kurumiya S, Hino K, Karasawa T.
    J Pharmacol Exp Ther; 1993 Jan; 264(1):158-65. PubMed ID: 8093723
    [Abstract] [Full Text] [Related]

  • 14. 3H-DOB (4-bromo-2,5-dimethoxyphenylisopropylamine) labels a guanyl nucleotide-sensitive state of cortical 5-HT2 receptors.
    Lyon RA, Davis KH, Titeler M.
    Mol Pharmacol; 1987 Feb; 31(2):194-9. PubMed ID: 3543649
    [Abstract] [Full Text] [Related]

  • 15. Pharmacology of risperidone (R 64 766), a new antipsychotic with serotonin-S2 and dopamine-D2 antagonistic properties.
    Janssen PA, Niemegeers CJ, Awouters F, Schellekens KH, Megens AA, Meert TF.
    J Pharmacol Exp Ther; 1988 Feb; 244(2):685-93. PubMed ID: 2450200
    [Abstract] [Full Text] [Related]

  • 16. 5-HT2-receptor antagonists: alpha 1- vs. 5-HT2-receptor blocking properties in blood vessels.
    Cohen ML, Schenck KW, Kurz KD.
    J Cardiovasc Pharmacol; 1988 Feb; 11 Suppl 1():S25-9. PubMed ID: 2459510
    [Abstract] [Full Text] [Related]

  • 17. In vivo binding of [3H]ketanserin on serotonin S2-receptors in rat brain.
    Laduron PM, Janssen PF, Leysen JE.
    Eur J Pharmacol; 1982 Jun 16; 81(1):43-8. PubMed ID: 7117369
    [Abstract] [Full Text] [Related]

  • 18. Computer imaging and analysis of dopamine (D2) and serotonin (S2) binding sites in rat basal ganglia or neocortex labeled by [3H]spiroperidol.
    Altar CA, Kim H, Marshall JF.
    J Pharmacol Exp Ther; 1985 May 16; 233(2):527-38. PubMed ID: 3889277
    [Abstract] [Full Text] [Related]

  • 19. N-(p-isothiocyanatophenethyl)spiperone, a selective and irreversible antagonist of D2 dopamine receptors in brain.
    Xu SX, Hatada Y, Black LE, Creese I, Sibley DR.
    J Pharmacol Exp Ther; 1991 May 16; 257(2):608-15. PubMed ID: 1674530
    [Abstract] [Full Text] [Related]

  • 20. Functional interaction between serotonin-S2 and dopamine-D2 neurotransmission as revealed by selective antagonism of hyper-reactivity to tryptamine and apomorphine.
    Awouters F, Niemegeers CJ, Megens AA, Janssen PA.
    J Pharmacol Exp Ther; 1990 Sep 16; 254(3):945-51. PubMed ID: 1697623
    [Abstract] [Full Text] [Related]

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