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229 related items for PubMed ID: 28623785

  • 1. In vitro studies on nobiletin isolated from citrus plants and the bioactive metabolites, inhibitory action against gelatinase enzymatic activity and the molecular mechanisms in human retinal Müller cell line.
    Miyata Y, Nagase T, Katsura Y, Takahashi H, Natsugari H, Oshitari T, Kosano H.
    Biomed Pharmacother; 2017 Sep; 93():70-80. PubMed ID: 28623785
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and -9 in human fibrosarcoma HT-1080 cells.
    Sato T, Koike L, Miyata Y, Hirata M, Mimaki Y, Sashida Y, Yano M, Ito A.
    Cancer Res; 2002 Feb 15; 62(4):1025-9. PubMed ID: 11861377
    [Abstract] [Full Text] [Related]

  • 3. Activation of protein kinase C betaII/epsilon-c-Jun NH2-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin.
    Miyata Y, Sato T, Yano M, Ito A.
    Mol Cancer Ther; 2004 Jul 15; 3(7):839-47. PubMed ID: 15252145
    [Abstract] [Full Text] [Related]

  • 4. Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells.
    Lee YC, Cheng TH, Lee JS, Chen JH, Liao YC, Fong Y, Wu CH, Shih YW.
    Mol Cell Biochem; 2011 Jan 15; 347(1-2):103-15. PubMed ID: 20963626
    [Abstract] [Full Text] [Related]

  • 5. [Structure Activity Relationship Study of Polymethoxylated Flavones Targeted Retinal Müller Cells for Prevention of Retinal Diseases].
    Miyata Y.
    Yakugaku Zasshi; 2021 Jan 15; 141(1):41-45. PubMed ID: 33390446
    [Abstract] [Full Text] [Related]

  • 6. Regulation of Endothelium-Reticulum-Stress-Mediated Apoptotic Cell Death by a Polymethoxylated Flavone, Nobiletin, Through the Inhibition of Nuclear Translocation of Glyceraldehyde 3-Phosphate Dehydrogenase in Retinal Müller Cells.
    Miyata Y, Matsumoto K, Kusano S, Kusakabe Y, Katsura Y, Oshitari T, Kosano H.
    Cells; 2021 Mar 17; 10(3):. PubMed ID: 33802903
    [Abstract] [Full Text] [Related]

  • 7. Efficacy of nobiletin, a citrus flavonoid, in the treatment of the cardiovascular dysfunction of diabetes in rats.
    Parkar NA, Bhatt LK, Addepalli V.
    Food Funct; 2016 Jul 13; 7(7):3121-9. PubMed ID: 27279123
    [Abstract] [Full Text] [Related]

  • 8. Citrus peel polymethoxyflavones nobiletin and tangeretin suppress LPS- and IgE-mediated activation of human intestinal mast cells.
    Hagenlocher Y, Feilhauer K, Schäffer M, Bischoff SC, Lorentz A.
    Eur J Nutr; 2017 Jun 13; 56(4):1609-1620. PubMed ID: 27021766
    [Abstract] [Full Text] [Related]

  • 9. Antimetastatic effect of nobiletin through the down-regulation of CXC chemokine receptor type 4 and matrix metallopeptidase-9.
    Baek SH, Kim SM, Nam D, Lee JH, Ahn KS, Choi SH, Kim SH, Shim BS, Chang IM, Ahn KS.
    Pharm Biol; 2012 Oct 13; 50(10):1210-8. PubMed ID: 22853317
    [Abstract] [Full Text] [Related]

  • 10. Nobiletin, a Polymethoxylated Flavone, Inhibits Glioma Cell Growth and Migration via Arresting Cell Cycle and Suppressing MAPK and Akt Pathways.
    Lien LM, Wang MJ, Chen RJ, Chiu HC, Wu JL, Shen MY, Chou DS, Sheu JR, Lin KH, Lu WJ.
    Phytother Res; 2016 Feb 13; 30(2):214-21. PubMed ID: 26560814
    [Abstract] [Full Text] [Related]

  • 11. Nobiletin suppresses MMP-9 expression through modulation of p38 MAPK activity in human dermal fibrobalsts.
    Kim JJ, Korm S, Kim WS, Kim OS, Lee JS, Min HG, Chin YW, Cha HJ.
    Biol Pharm Bull; 2014 Feb 13; 37(1):158-63. PubMed ID: 24389490
    [Abstract] [Full Text] [Related]

  • 12. 6-demethoxynobiletin, a nobiletin-analog citrus flavonoid, enhances extracellular signal-regulated kinase phosphorylation in PC12D cells.
    Kimura J, Nemoto K, Yokosuka A, Mimaki Y, Degawa M, Ohizumi Y.
    Biol Pharm Bull; 2013 Feb 13; 36(10):1646-9. PubMed ID: 23934345
    [Abstract] [Full Text] [Related]

  • 13. Nobiletin, a citrus flavonoid, activates vasodilator-stimulated phosphoprotein in human platelets through non-cyclic nucleotide-related mechanisms.
    Jayakumar T, Lin KC, Lu WJ, Lin CY, Pitchairaj G, Li JY, Sheu JR.
    Int J Mol Med; 2017 Jan 13; 39(1):174-182. PubMed ID: 27959381
    [Abstract] [Full Text] [Related]

  • 14. A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells.
    Miyata Y, Sato T, Imada K, Dobashi A, Yano M, Ito A.
    Biochem Biophys Res Commun; 2008 Feb 01; 366(1):168-73. PubMed ID: 18053806
    [Abstract] [Full Text] [Related]

  • 15. A citrus flavonoid, nobiletin, suppresses production and gene expression of matrix metalloproteinase 9/gelatinase B in rabbit synovial fibroblasts.
    Ishiwa J, Sato T, Mimaki Y, Sashida Y, Yano M, Ito A.
    J Rheumatol; 2000 Jan 01; 27(1):20-5. PubMed ID: 10648013
    [Abstract] [Full Text] [Related]

  • 16. Nobiletin inhibits human osteosarcoma cells metastasis by blocking ERK and JNK-mediated MMPs expression.
    Cheng HL, Hsieh MJ, Yang JS, Lin CW, Lue KH, Lu KH, Yang SF.
    Oncotarget; 2016 Jun 07; 7(23):35208-23. PubMed ID: 27144433
    [Abstract] [Full Text] [Related]

  • 17. Novel anti-inflammatory actions of nobiletin, a citrus polymethoxy flavonoid, on human synovial fibroblasts and mouse macrophages.
    Lin N, Sato T, Takayama Y, Mimaki Y, Sashida Y, Yano M, Ito A.
    Biochem Pharmacol; 2003 Jun 15; 65(12):2065-71. PubMed ID: 12787887
    [Abstract] [Full Text] [Related]

  • 18. Interactive effects of polymethoxy flavones from Citrus on cell growth inhibition in human neuroblastoma SH-SY5Y cells.
    Akao Y, Itoh T, Ohguchi K, Iinuma M, Nozawa Y.
    Bioorg Med Chem; 2008 Mar 15; 16(6):2803-10. PubMed ID: 18282757
    [Abstract] [Full Text] [Related]

  • 19. Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured hippocampal neurons: identification of the substances responsible for the pharmacological action.
    Kawahata I, Yoshida M, Sun W, Nakajima A, Lai Y, Osaka N, Matsuzaki K, Yokosuka A, Mimaki Y, Naganuma A, Tomioka Y, Yamakuni T.
    J Neural Transm (Vienna); 2013 Oct 15; 120(10):1397-409. PubMed ID: 23588349
    [Abstract] [Full Text] [Related]

  • 20. Protein kinase C-mediated regulation of matrix metalloproteinase and tissue inhibitor of metalloproteinase production in a human retinal müller cells.
    Miyata Y, Kase M, Sugita Y, Shimada A, Nagase T, Katsura Y, Kosano H.
    Curr Eye Res; 2012 Sep 15; 37(9):842-9. PubMed ID: 22667460
    [Abstract] [Full Text] [Related]

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