These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

201 related items for PubMed ID: 28630914

  • 1. Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin.
    Hu LR, Ackermann MA, Hecker PA, Prosser BL, King B, O'Connell KA, Grogan A, Meyer LC, Berndsen CE, Wright NT, Jonathan Lederer W, Kontrogianni-Konstantopoulos A.
    Sci Adv; 2017 Jun; 3(6):e1603081. PubMed ID: 28630914
    [Abstract] [Full Text] [Related]

  • 2. Deletion of obscurin immunoglobulin domains Ig58/59 leads to age-dependent cardiac remodeling and arrhythmia.
    Grogan A, Coleman A, Joca H, Granzier H, Russel MW, Ward CW, Kontrogianni-Konstantopoulos A.
    Basic Res Cardiol; 2020 Sep 10; 115(6):60. PubMed ID: 32910221
    [Abstract] [Full Text] [Related]

  • 3. Proteomic Analysis of Myocardia Containing the Obscurin R4344Q Mutation Linked to Hypertrophic Cardiomyopathy.
    Hu LR, Kontrogianni-Konstantopoulos A.
    Front Physiol; 2020 Sep 10; 11():478. PubMed ID: 32528308
    [Abstract] [Full Text] [Related]

  • 4. When is an obscurin variant pathogenic? The impact of Arg4344Gln and Arg4444Trp variants on protein-protein interactions and protein stability.
    Fukuzawa A, Koch D, Grover S, Rees M, Gautel M.
    Hum Mol Genet; 2021 Jun 09; 30(12):1131-1141. PubMed ID: 33438037
    [Abstract] [Full Text] [Related]

  • 5. Unraveling obscurins in heart disease.
    Grogan A, Kontrogianni-Konstantopoulos A.
    Pflugers Arch; 2019 May 09; 471(5):735-743. PubMed ID: 30099631
    [Abstract] [Full Text] [Related]

  • 6. A novel human R25C-phospholamban mutation is associated with super-inhibition of calcium cycling and ventricular arrhythmia.
    Liu GS, Morales A, Vafiadaki E, Lam CK, Cai WF, Haghighi K, Adly G, Hershberger RE, Kranias EG.
    Cardiovasc Res; 2015 Jul 01; 107(1):164-74. PubMed ID: 25852082
    [Abstract] [Full Text] [Related]

  • 7. Alterations in cytoskeletal and Ca2+ cycling regulators in atria lacking the obscurin Ig58/59 module.
    Grogan A, Huang W, Brong A, Kane MA, Kontrogianni-Konstantopoulos A.
    Front Cardiovasc Med; 2023 Jul 01; 10():1085840. PubMed ID: 37304957
    [Abstract] [Full Text] [Related]

  • 8. Intracellular calcium current disorder and disease phenotype in OBSCN mutant iPSC-based cardiomyocytes in arrhythmogenic right ventricular cardiomyopathy.
    Chen P, Xiao Y, Wang Y, Zheng Z, Chen L, Yang X, Li J, Wu W, Zhang S.
    Theranostics; 2020 Jul 01; 10(24):11215-11229. PubMed ID: 33042279
    [Abstract] [Full Text] [Related]

  • 9. Dilated cardiomyopathy mutations in thin-filament regulatory proteins reduce contractility, suppress systolic Ca2+, and activate NFAT and Akt signaling.
    Robinson P, Sparrow AJ, Patel S, Malinowska M, Reilly SN, Zhang YH, Casadei B, Watkins H, Redwood C.
    Am J Physiol Heart Circ Physiol; 2020 Aug 01; 319(2):H306-H319. PubMed ID: 32618513
    [Abstract] [Full Text] [Related]

  • 10. Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias.
    Haghighi K, Pritchard TJ, Liu GS, Singh VP, Bidwell P, Lam CK, Vafiadaki E, Das P, Ma J, Kunduri S, Sanoudou D, Florea S, Vanderbilt E, Wang HS, Rubinstein J, Hajjar RJ, Kranias EG.
    J Mol Cell Cardiol; 2015 Dec 01; 89(Pt B):349-59. PubMed ID: 26455482
    [Abstract] [Full Text] [Related]

  • 11. Impaired calcium homeostasis is associated with sudden cardiac death and arrhythmias in a genetic equivalent mouse model of the human HRC-Ser96Ala variant.
    Tzimas C, Johnson DM, Santiago DJ, Vafiadaki E, Arvanitis DA, Davos CH, Varela A, Athanasiadis NC, Dimitriou C, Katsimpoulas M, Sonntag S, Kryzhanovska M, Shmerling D, Lehnart SE, Sipido KR, Kranias EG, Sanoudou D.
    Cardiovasc Res; 2017 Sep 01; 113(11):1403-1417. PubMed ID: 28859293
    [Abstract] [Full Text] [Related]

  • 12. Sarcoplasmic reticulum calcium overloading in junctin deficiency enhances cardiac contractility but increases ventricular automaticity.
    Yuan Q, Fan GC, Dong M, Altschafl B, Diwan A, Ren X, Hahn HH, Zhao W, Waggoner JR, Jones LR, Jones WK, Bers DM, Dorn GW, Wang HS, Valdivia HH, Chu G, Kranias EG.
    Circulation; 2007 Jan 23; 115(3):300-9. PubMed ID: 17224479
    [Abstract] [Full Text] [Related]

  • 13. αB-Crystallin R120G variant causes cardiac arrhythmias and alterations in the expression of Ca(2+) -handling proteins and endoplasmic reticulum stress in mice.
    Jiao Q, Sanbe A, Zhang X, Liu JP, Minamisawa S.
    Clin Exp Pharmacol Physiol; 2014 Aug 23; 41(8):589-99. PubMed ID: 24825000
    [Abstract] [Full Text] [Related]

  • 14. Elevated Ca2+ transients and increased myofibrillar power generation cause cardiac hypercontractility in a model of Noonan syndrome with multiple lentigines.
    Clay SA, Domeier TL, Hanft LM, McDonald KS, Krenz M.
    Am J Physiol Heart Circ Physiol; 2015 May 01; 308(9):H1086-95. PubMed ID: 25724491
    [Abstract] [Full Text] [Related]

  • 15. Hypertrophic cardiomyopathy mutations increase myofilament Ca2+ buffering, alter intracellular Ca2+ handling, and stimulate Ca2+-dependent signaling.
    Robinson P, Liu X, Sparrow A, Patel S, Zhang YH, Casadei B, Watkins H, Redwood C.
    J Biol Chem; 2018 Jul 06; 293(27):10487-10499. PubMed ID: 29760186
    [Abstract] [Full Text] [Related]

  • 16. Sarcoplasmic reticulum adenosine triphosphatase overexpression in the L-type Ca2+ channel mouse results in cardiomyopathy and Ca2+ -induced arrhythmogenesis.
    Rubio M, Bodi I, Fuller-Bicer GA, Hahn HS, Periasamy M, Schwartz A.
    J Cardiovasc Pharmacol Ther; 2005 Dec 06; 10(4):235-49. PubMed ID: 16382260
    [Abstract] [Full Text] [Related]

  • 17. Structural analysis of obscurin gene in hypertrophic cardiomyopathy.
    Arimura T, Matsumoto Y, Okazaki O, Hayashi T, Takahashi M, Inagaki N, Hinohara K, Ashizawa N, Yano K, Kimura A.
    Biochem Biophys Res Commun; 2007 Oct 19; 362(2):281-7. PubMed ID: 17716621
    [Abstract] [Full Text] [Related]

  • 18. Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity.
    Rajan S, Ahmed RP, Jagatheesan G, Petrashevskaya N, Boivin GP, Urboniene D, Arteaga GM, Wolska BM, Solaro RJ, Liggett SB, Wieczorek DF.
    Circ Res; 2007 Jul 20; 101(2):205-14. PubMed ID: 17556658
    [Abstract] [Full Text] [Related]

  • 19. Impaired Intracellular Ca2+ Dynamics, M-Band and Sarcomere Fragility in Skeletal Muscles of Obscurin KO Mice.
    Pierantozzi E, Szentesi P, Paolini C, Dienes B, Fodor J, Oláh T, Colombini B, Rassier DE, Rubino EM, Lange S, Rossi D, Csernoch L, Bagni MA, Reggiani C, Sorrentino V.
    Int J Mol Sci; 2022 Jan 24; 23(3):. PubMed ID: 35163243
    [Abstract] [Full Text] [Related]

  • 20. In Vivo Analysis of Troponin C Knock-In (A8V) Mice: Evidence that TNNC1 Is a Hypertrophic Cardiomyopathy Susceptibility Gene.
    Martins AS, Parvatiyar MS, Feng HZ, Bos JM, Gonzalez-Martinez D, Vukmirovic M, Turna RS, Sanchez-Gonzalez MA, Badger CD, Zorio DAR, Singh RK, Wang Y, Jin JP, Ackerman MJ, Pinto JR.
    Circ Cardiovasc Genet; 2015 Oct 24; 8(5):653-664. PubMed ID: 26304555
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 11.