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437 related items for PubMed ID: 28631500

  • 1. Pancreatic-β-cell survival and proliferation are promoted by protein kinase G type Iα and downstream regulation of AKT/FOXO1.
    Wong JC, Vo V, Gorjala P, Fiscus RR.
    Diab Vasc Dis Res; 2017 Sep; 14(5):434-449. PubMed ID: 28631500
    [Abstract] [Full Text] [Related]

  • 2. Essential roles of the nitric oxide (no)/cGMP/protein kinase G type-Iα (PKG-Iα) signaling pathway and the atrial natriuretic peptide (ANP)/cGMP/PKG-Iα autocrine loop in promoting proliferation and cell survival of OP9 bone marrow stromal cells.
    Wong JC, Fiscus RR.
    J Cell Biochem; 2011 Mar; 112(3):829-39. PubMed ID: 21328456
    [Abstract] [Full Text] [Related]

  • 3. Cyclic GMP/protein kinase G type-Iα (PKG-Iα) signaling pathway promotes CREB phosphorylation and maintains higher c-IAP1, livin, survivin, and Mcl-1 expression and the inhibition of PKG-Iα kinase activity synergizes with cisplatin in non-small cell lung cancer cells.
    Wong JC, Bathina M, Fiscus RR.
    J Cell Biochem; 2012 Nov; 113(11):3587-98. PubMed ID: 22740515
    [Abstract] [Full Text] [Related]

  • 4. Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction.
    Meng Z, Lv J, Luo Y, Lin Y, Zhu Y, Nie J, Yang T, Sun Y, Han X.
    Endocrinology; 2009 Dec; 150(12):5284-93. PubMed ID: 19837872
    [Abstract] [Full Text] [Related]

  • 5. Nitric oxide regulates AKT phosphorylation and nuclear translocation in cultured retinal cells.
    Mejía-García TA, Portugal CC, Encarnação TG, Prado MA, Paes-de-Carvalho R.
    Cell Signal; 2013 Dec; 25(12):2424-39. PubMed ID: 23958999
    [Abstract] [Full Text] [Related]

  • 6. Atrial natriuretic peptide promotes pancreatic islet beta-cell growth and Akt/Foxo1a/cyclin D2 signaling.
    You H, Laychock SG.
    Endocrinology; 2009 Dec; 150(12):5455-65. PubMed ID: 19837876
    [Abstract] [Full Text] [Related]

  • 7. Protein kinase G type Ialpha activity in human ovarian cancer cells significantly contributes to enhanced Src activation and DNA synthesis/cell proliferation.
    Leung EL, Wong JC, Johlfs MG, Tsang BK, Fiscus RR.
    Mol Cancer Res; 2010 Apr; 8(4):578-91. PubMed ID: 20371672
    [Abstract] [Full Text] [Related]

  • 8. Protective action of liraglutide in beta cells under lipotoxic stress via PI3K/Akt/FoxO1 pathway.
    Shao S, Nie M, Chen C, Chen X, Zhang M, Yuan G, Yu X, Yang Y.
    J Cell Biochem; 2014 Jun; 115(6):1166-75. PubMed ID: 24415347
    [Abstract] [Full Text] [Related]

  • 9. Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3',5'-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-Kinase/Akt signaling.
    Granata R, Settanni F, Biancone L, Trovato L, Nano R, Bertuzzi F, Destefanis S, Annunziata M, Martinetti M, Catapano F, Ghè C, Isgaard J, Papotti M, Ghigo E, Muccioli G.
    Endocrinology; 2007 Feb; 148(2):512-29. PubMed ID: 17068144
    [Abstract] [Full Text] [Related]

  • 10. eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells.
    Díaz-Troya S, Najib S, Sánchez-Margalet V.
    Regul Pept; 2005 Feb 15; 125(1-3):41-6. PubMed ID: 15582712
    [Abstract] [Full Text] [Related]

  • 11. nitric oxide triggers the phosphatidylinositol 3-kinase/Akt survival pathway in insulin-producing RINm5F cells by arousing Src to activate insulin receptor substrate-1.
    Tejedo JR, Cahuana GM, Ramírez R, Esbert M, Jiménez J, Sobrino F, Bedoya FJ.
    Endocrinology; 2004 May 15; 145(5):2319-27. PubMed ID: 14764634
    [Abstract] [Full Text] [Related]

  • 12. Apolipoprotein A-I increases insulin secretion and production from pancreatic β-cells via a G-protein-cAMP-PKA-FoxO1-dependent mechanism.
    Cochran BJ, Bisoendial RJ, Hou L, Glaros EN, Rossy J, Thomas SR, Barter PJ, Rye KA.
    Arterioscler Thromb Vasc Biol; 2014 Oct 15; 34(10):2261-7. PubMed ID: 25147338
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of Foxo1 mediates protective effects of ghrelin against lipotoxicity in MIN6 pancreatic beta-cells.
    Wang W, Liu Y, Chen Y, Cao C, Xiang Y, Zhang D, Han L, Zhao H, Liu G.
    Peptides; 2010 Feb 15; 31(2):307-14. PubMed ID: 19944124
    [Abstract] [Full Text] [Related]

  • 14. Protein kinase G activity prevents pathological-level nitric oxide-induced apoptosis and promotes DNA synthesis/cell proliferation in vascular smooth muscle cells.
    Wong JC, Fiscus RR.
    Cardiovasc Pathol; 2010 Feb 15; 19(6):e221-31. PubMed ID: 20060325
    [Abstract] [Full Text] [Related]

  • 15. Liraglutide, a human glucagon-like peptide-1 analogue, stimulates AKT-dependent survival signalling and inhibits pancreatic β-cell apoptosis.
    Kapodistria K, Tsilibary EP, Kotsopoulou E, Moustardas P, Kitsiou P.
    J Cell Mol Med; 2018 Jun 15; 22(6):2970-2980. PubMed ID: 29524296
    [Abstract] [Full Text] [Related]

  • 16. Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression.
    Kim SJ, Winter K, Nian C, Tsuneoka M, Koda Y, McIntosh CH.
    J Biol Chem; 2005 Jun 10; 280(23):22297-307. PubMed ID: 15817464
    [Abstract] [Full Text] [Related]

  • 17. Nitric oxide mediates the survival action of IGF-1 and insulin in pancreatic beta cells.
    Cahuana GM, Tejedo JR, Hmadcha A, Ramírez R, Cuesta AL, Soria B, Martin F, Bedoya FJ.
    Cell Signal; 2008 Feb 10; 20(2):301-10. PubMed ID: 18023142
    [Abstract] [Full Text] [Related]

  • 18. Preadipocyte factor 1 induces pancreatic ductal cell differentiation into insulin-producing cells.
    Rhee M, Lee SH, Kim JW, Ham DS, Park HS, Yang HK, Shin JY, Cho JH, Kim YB, Youn BS, Sul HS, Yoon KH.
    Sci Rep; 2016 Apr 05; 6():23960. PubMed ID: 27044861
    [Abstract] [Full Text] [Related]

  • 19. High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cells.
    Venieratos PD, Drossopoulou GI, Kapodistria KD, Tsilibary EC, Kitsiou PV.
    Cell Signal; 2010 May 05; 22(5):791-800. PubMed ID: 20067833
    [Abstract] [Full Text] [Related]

  • 20. L-Arginine supplementation improves insulin sensitivity and beta cell function in the offspring of diabetic rats through AKT and PDX-1 activation.
    Carvalho DS, Diniz MM, Haidar AA, Cavanal MF, da Silva Alves E, Carpinelli AR, Gil FZ, Hirata AE.
    Eur J Pharmacol; 2016 Nov 15; 791():780-787. PubMed ID: 27717730
    [Abstract] [Full Text] [Related]

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