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150 related items for PubMed ID: 286368

  • 1. Extrahepatic tissue distribution, covalent binding, and toxicity of halothane in control and phenobarbital-pretreated rats.
    Rao GS, Grumley JO.
    Pharmacol Ther Dent; 1978; 3(2-4):101-9. PubMed ID: 286368
    [Abstract] [Full Text] [Related]

  • 2. A study of the mechanism of halothane-induced liver necrosis. Role of covalent binding of halothane metabolites to liver proteins in the rat.
    Rao GS.
    J Med Chem; 1977 Feb; 20(2):262-5. PubMed ID: 836497
    [Abstract] [Full Text] [Related]

  • 3. Comparison of covalent binding from halothane metabolism in hepatic microsomes from phenobarbital-induced and hyperthyroid rats.
    Smith AC, Roberts SM, James RC, Berman LM, Harbison RD.
    Xenobiotica; 1988 Aug; 18(8):991-1001. PubMed ID: 3188577
    [Abstract] [Full Text] [Related]

  • 4. An animal model of halothane hepatotoxicity: roles of enzyme induction and hypoxia.
    McLain GE, Sipes IG, Brown BR.
    Anesthesiology; 1979 Oct; 51(4):321-6. PubMed ID: 484893
    [Abstract] [Full Text] [Related]

  • 5. Studies of the toxicity of I-653, halothane, and isoflurane in enzyme-induced, hypoxic rats.
    Eger EI, Johnson BH, Strum DP, Ferrell LD.
    Anesth Analg; 1987 Dec; 66(12):1227-9. PubMed ID: 3688493
    [Abstract] [Full Text] [Related]

  • 6. Evidence for hepatic formation, export and covalent binding of reactive naphthalene metabolites in extrahepatic tissues in vivo.
    Buckpitt AR, Warren DL.
    J Pharmacol Exp Ther; 1983 Apr; 225(1):8-16. PubMed ID: 6834280
    [Abstract] [Full Text] [Related]

  • 7. Nitrous oxide does not hinder the repair of halothane-induced hepatic injury in the rat.
    Fassoulaki A, Eger EI, Johnson BH, Ferrell LD, Smuckler EA, Cahalan MK, Eger RR, Harper MH.
    Anesth Analg; 1985 May; 64(5):465-7. PubMed ID: 3994007
    [Abstract] [Full Text] [Related]

  • 8. Bioactivation and covalent binding of halothane to liver macromolecules.
    Sipes IG, Podolsky TL, Brown BR.
    Environ Health Perspect; 1977 Dec; 21():171-8. PubMed ID: 612442
    [Abstract] [Full Text] [Related]

  • 9. Late dimethyl sulfoxide administration provides a protective action against chemically induced injury in both the liver and the kidney.
    Lind RC, Gandolfi AJ.
    Toxicol Appl Pharmacol; 1997 Jan; 142(1):201-7. PubMed ID: 9007050
    [Abstract] [Full Text] [Related]

  • 10. Hypoxia and halothane metabolism in vivo: release of inorganic fluoride and halothane metabolite binding to cellular constituents.
    Widger LA, Gandolfi AJ, Van Dyke RA.
    Anesthesiology; 1976 Mar; 44(3):197-201. PubMed ID: 1267885
    [Abstract] [Full Text] [Related]

  • 11. Effects of anticonvulsant agents on halothane-induced liver injury in human subjects and experimental animals.
    Nomura F, Hatano H, Ohnishi K, Akikusa B, Okuda K.
    Hepatology; 1986 Mar; 6(5):952-6. PubMed ID: 3093358
    [Abstract] [Full Text] [Related]

  • 12. Genetic differences in reductive metabolism and hepatotoxicity of halothane in three rat strains.
    Gourlay GK, Adams JF, Cousins MJ, Hall P.
    Anesthesiology; 1981 Aug; 55(2):96-103. PubMed ID: 7258721
    [Abstract] [Full Text] [Related]

  • 13. The absence of effect of phenobarbital on halothane toxicity.
    Barth ML, Cornish HH.
    Res Commun Chem Pathol Pharmacol; 1973 Jan; 5(1):149-62. PubMed ID: 4686098
    [No Abstract] [Full Text] [Related]

  • 14. Comparative toxicity of halothane, isoflurane, hypoxia, and phenobarbital induction in monolayer cultures of rat hepatocytes.
    Schieble TM, Costa AK, Heffel DF, Trudell JR.
    Anesthesiology; 1988 Apr; 68(4):485-94. PubMed ID: 3354886
    [Abstract] [Full Text] [Related]

  • 15. The kidney as a novel target tissue for protein adduct formation associated with metabolism of halothane and the candidate chlorofluorocarbon replacement 2,2-dichloro-1,1,1-trifluoroethane.
    Huwyler J, Aeschlimann D, Christen U, Gut J.
    Eur J Biochem; 1992 Jul 01; 207(1):229-38. PubMed ID: 1628651
    [Abstract] [Full Text] [Related]

  • 16. Time course of 72-kilodalton heat shock protein induction and appearance of trifluoroacetyl adducts in livers of halothane-exposed rats.
    Lin WQ, van Dyke RA, Marsh HM, Trudell JR.
    Mol Pharmacol; 1994 Oct 01; 46(4):639-43. PubMed ID: 7526150
    [Abstract] [Full Text] [Related]

  • 17. 2-Methylfuran toxicity in rats--role of metabolic activation in vivo.
    Ravindranath V, McMenamin MG, Dees JH, Boyd MR.
    Toxicol Appl Pharmacol; 1986 Aug 01; 85(1):78-91. PubMed ID: 3726888
    [Abstract] [Full Text] [Related]

  • 18. Hepatic injury induced by anesthetic agents in rats.
    Shingu K, Eger EI, Johnson BH, Van Dyke RA, Lurz FW, Harper MH, Cheng A.
    Anesth Analg; 1983 Feb 01; 62(2):140-5. PubMed ID: 6829914
    [Abstract] [Full Text] [Related]

  • 19. Hepatic necrosis caused by halothane and hypoxia in phenobarbital-treated rats.
    Ross WT, Daggy BP, Cardell RR.
    Anesthesiology; 1979 Oct 01; 51(4):327-33. PubMed ID: 484894
    [No Abstract] [Full Text] [Related]

  • 20. I-653 resists degradation in rats.
    Koblin DD, Eger EI, Johnson BH, Konopka K, Waskell L.
    Anesth Analg; 1988 Jun 01; 67(6):534-8. PubMed ID: 3377207
    [Abstract] [Full Text] [Related]

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