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Journal Abstract Search


809 related items for PubMed ID: 28646304

  • 1. NDRG2 knockdown promotes fibrosis in renal tubular epithelial cells through TGF-β1/Smad3 pathway.
    Jin Z, Gu C, Tian F, Jia Z, Yang J.
    Cell Tissue Res; 2017 Sep; 369(3):603-610. PubMed ID: 28646304
    [Abstract] [Full Text] [Related]

  • 2. Smad2 and Smad3 play antagonistic roles in high glucose-induced renal tubular fibrosis via the regulation of SnoN.
    Wang Y, Zhang X, Mao Y, Liang L, Liu L, Peng W, Liu H, Xiao Y, Zhang Y, Zhang F, Shi M, Liu L, Guo B.
    Exp Mol Pathol; 2020 Apr; 113():104375. PubMed ID: 31917288
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  • 3. Smad3 linker phosphorylation attenuates Smad3 transcriptional activity and TGF-β1/Smad3-induced epithelial-mesenchymal transition in renal epithelial cells.
    Bae E, Kim SJ, Hong S, Liu F, Ooshima A.
    Biochem Biophys Res Commun; 2012 Oct 26; 427(3):593-9. PubMed ID: 23022526
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  • 4. MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2.
    Tang H, Fan D, Lei CT, Ye C, Gao P, Chen S, Meng XF, Su H, Zhang C.
    J Mol Med (Berl); 2016 Nov 26; 94(11):1297-1307. PubMed ID: 27488450
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  • 5. Lysine-specific demethylase 1 induced epithelial-mesenchymal transition and promoted renal fibrosis through Jagged-1/Notch signaling pathway.
    Zhang H, Xing J, Zhao L.
    Hum Exp Toxicol; 2021 Dec 26; 40(12_suppl):S203-S214. PubMed ID: 34396798
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  • 6. Pirfenidone Attenuates Renal Tubulointerstitial Fibrosis through Inhibiting miR-21.
    Bi L, Huang Y, Li J, Yang X, Hou G, Zhai P, Zhang Q, Alhaji AA, Yang Y, Liu B.
    Nephron; 2022 Dec 26; 146(1):110-120. PubMed ID: 34724669
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  • 7. Novel RAS inhibitor 25-O-methylalisol F attenuates epithelial-to-mesenchymal transition and tubulo-interstitial fibrosis by selectively inhibiting TGF-β-mediated Smad3 phosphorylation.
    Chen H, Yang T, Wang MC, Chen DQ, Yang Y, Zhao YY.
    Phytomedicine; 2018 Mar 15; 42():207-218. PubMed ID: 29655688
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  • 8. Tumor suppressor ataxia telangiectasia mutated functions downstream of TGF-β1 in orchestrating profibrotic responses.
    Overstreet JM, Samarakoon R, Cardona-Grau D, Goldschmeding R, Higgins PJ.
    FASEB J; 2015 Apr 15; 29(4):1258-68. PubMed ID: 25480384
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  • 9. Qinggan Huoxue Recipe suppresses epithelial-to-mesenchymal transition in alcoholic liver fibrosis through TGF-β1/Smad signaling pathway.
    Wu T, Chen JM, Xiao TG, Shu XB, Xu HC, Yang LL, Xing LJ, Zheng PY, Ji G.
    World J Gastroenterol; 2016 May 21; 22(19):4695-706. PubMed ID: 27217701
    [Abstract] [Full Text] [Related]

  • 10. miR-21 overexpression enhances TGF-β1-induced epithelial-to-mesenchymal transition by target smad7 and aggravates renal damage in diabetic nephropathy.
    Wang JY, Gao YB, Zhang N, Zou DW, Wang P, Zhu ZY, Li JY, Zhou SN, Wang SC, Wang YY, Yang JK.
    Mol Cell Endocrinol; 2014 Jul 05; 392(1-2):163-72. PubMed ID: 24887517
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  • 11. Nerve growth factor exposure promotes tubular epithelial-mesenchymal transition via TGF-β1 signaling activation.
    Vizza D, Perri A, Toteda G, Lupinacci S, Leone F, Gigliotti P, Lofaro D, La Russa A, Bonofiglio R.
    Growth Factors; 2015 Jul 05; 33(3):169-80. PubMed ID: 26066770
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  • 12. Src Homology 2 Domain-Containing Inositol 5'-Phosphatase Ameliorates High Glucose-Induced Extracellular Matrix Deposition via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway in Renal Tubular Epithelial Cells.
    Li F, Li L, Hao J, Liu S, Duan H.
    J Cell Biochem; 2017 Aug 05; 118(8):2271-2284. PubMed ID: 28075049
    [Abstract] [Full Text] [Related]

  • 13. Cell phenotype-specific down-regulation of Smad3 involves decreased gene activation as well as protein degradation.
    Poncelet AC, Schnaper HW, Tan R, Liu Y, Runyan CE.
    J Biol Chem; 2007 May 25; 282(21):15534-40. PubMed ID: 17400544
    [Abstract] [Full Text] [Related]

  • 14. BMP-7 inhibits renal fibrosis in diabetic nephropathy via miR-21 downregulation.
    Liu L, Wang Y, Yan R, Liang L, Zhou X, Liu H, Zhang X, Mao Y, Peng W, Xiao Y, Zhang F, Liu L, Shi M, Guo B.
    Life Sci; 2019 Dec 01; 238():116957. PubMed ID: 31655195
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  • 15. Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway.
    Qin MY, Huang SQ, Zou XQ, Zhong XB, Yang YF, Zhang YT, Mi ZC, Zhang YS, Huang ZG.
    J Ethnopharmacol; 2021 Nov 15; 280():114414. PubMed ID: 34314804
    [Abstract] [Full Text] [Related]

  • 16. EPA attenuates epithelial-mesenchymal transition and fibrosis through the TGF-β1/Smad3/ILK pathway in renal tubular epithelial HK-2 cells by up-regulating miR-541.
    Wei Z, Cao J, Zhang X, Yin D, Xu D, Lu G.
    Int J Clin Exp Pathol; 2019 Nov 15; 12(7):2516-2525. PubMed ID: 31934078
    [Abstract] [Full Text] [Related]

  • 17. Astragaloside IV attenuates high glucose-induced EMT by inhibiting the TGF-β/Smad pathway in renal proximal tubular epithelial cells.
    Wang YN, Zhao SL, Su YY, Feng JX, Wang S, Liao XM, Wang LN, Li JC, Meng P, Li HY, Zhang YF.
    Biosci Rep; 2020 Jun 26; 40(6):. PubMed ID: 32515466
    [Abstract] [Full Text] [Related]

  • 18. Cdc42-interacting protein-4 promotes TGF-Β1-induced epithelial-mesenchymal transition and extracellular matrix deposition in renal proximal tubular epithelial cells.
    Bai S, Zeng R, Zhou Q, Liao W, Zhang Y, Xu C, Han M, Pei G, Liu L, Liu X, Yao Y, Xu G.
    Int J Biol Sci; 2012 Jun 26; 8(6):859-69. PubMed ID: 22745576
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  • 19. Smad Anchor for Receptor Activation Regulates High Glucose-Induced EMT via Modulation of Smad2 and Smad3 Activities in Renal Tubular Epithelial Cells.
    Tang WB, Ling GH, Sun L, Zhang K, Zhu X, Zhou X, Liu FY.
    Nephron; 2015 Jun 26; 130(3):213-20. PubMed ID: 26159183
    [Abstract] [Full Text] [Related]

  • 20. WNT/β-catenin signal inhibitor IC-2-derived small-molecule compounds suppress TGF-β1-induced fibrogenic response of renal epithelial cells by inhibiting SMAD2/3 signalling.
    Hoi S, Tsuchiya H, Itaba N, Suzuki K, Oka H, Morimoto M, Takata T, Isomoto H, Shiota G.
    Clin Exp Pharmacol Physiol; 2020 Jun 26; 47(6):940-946. PubMed ID: 32012313
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