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211 related items for PubMed ID: 28653505
1. Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a. Fujimoto J, Nunomura-Nakamura S, Liu Y, Lang W, McDowell T, Jakubek Y, Ezzeddine D, Kapere Ochieng J, Petersen J, Davies G, Fukuoka J, Wistuba II, Ehli E, Fowler J, Scheet P, Kadara H. Int J Cancer; 2017 Oct 15; 141(8):1589-1599. PubMed ID: 28653505 [Abstract] [Full Text] [Related]
2. Comparative functional genomics analysis of NNK tobacco-carcinogen induced lung adenocarcinoma development in Gprc5a-knockout mice. Fujimoto J, Kadara H, Men T, van Pelt C, Lotan D, Lotan R. PLoS One; 2010 Jul 29; 5(7):e11847. PubMed ID: 20686609 [Abstract] [Full Text] [Related]
3. Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From Gprc5a-Deficient Murine Lung Adenocarcinoma With Somatic Kras Mutations. Daouk R, Hassane M, Bahmad HF, Sinjab A, Fujimoto J, Abou-Kheir W, Kadara H. Front Oncol; 2019 Jul 29; 9():207. PubMed ID: 31001473 [Abstract] [Full Text] [Related]
4. The mutational landscapes of genetic and chemical models of Kras-driven lung cancer. Westcott PM, Halliwill KD, To MD, Rashid M, Rust AG, Keane TM, Delrosario R, Jen KY, Gurley KE, Kemp CJ, Fredlund E, Quigley DA, Adams DJ, Balmain A. Nature; 2015 Jan 22; 517(7535):489-92. PubMed ID: 25363767 [Abstract] [Full Text] [Related]
6. Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up. Kadara H, Choi M, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S, Gibbons DL, Heymach J, Kaftan E, Townsend JP, Lynch TJ, Schlessinger J, Lee J, Lifton RP, Wistuba II, Herbst RS. Ann Oncol; 2017 Jan 01; 28(1):75-82. PubMed ID: 27687306 [Abstract] [Full Text] [Related]
7. Enhancement of lung tumorigenesis in a Gprc5a Knockout mouse by chronic extrinsic airway inflammation. Barta P, Van Pelt C, Men T, Dickey BF, Lotan R, Moghaddam SJ. Mol Cancer; 2012 Jan 12; 11():4. PubMed ID: 22239913 [Abstract] [Full Text] [Related]
8. Identification of the retinoic acid-inducible Gprc5a as a new lung tumor suppressor gene. Tao Q, Fujimoto J, Men T, Ye X, Deng J, Lacroix L, Clifford JL, Mao L, Van Pelt CS, Lee JJ, Lotan D, Lotan R. J Natl Cancer Inst; 2007 Nov 21; 99(22):1668-82. PubMed ID: 18000218 [Abstract] [Full Text] [Related]
9. An atlas of epithelial cell states and plasticity in lung adenocarcinoma. Han G, Sinjab A, Rahal Z, Lynch AM, Treekitkarnmongkol W, Liu Y, Serrano AG, Feng J, Liang K, Khan K, Lu W, Hernandez SD, Liu Y, Cao X, Dai E, Pei G, Hu J, Abaya C, Gomez-Bolanos LI, Peng F, Chen M, Parra ER, Cascone T, Sepesi B, Moghaddam SJ, Scheet P, Negrao MV, Heymach JV, Li M, Dubinett SM, Stevenson CS, Spira AE, Fujimoto J, Solis LM, Wistuba II, Chen J, Wang L, Kadara H. Nature; 2024 Mar 21; 627(8004):656-663. PubMed ID: 38418883 [Abstract] [Full Text] [Related]
10. Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis. Deng J, Fujimoto J, Ye XF, Men TY, Van Pelt CS, Chen YL, Lin XF, Kadara H, Tao Q, Lotan D, Lotan R. Cancer Prev Res (Phila); 2010 Apr 21; 3(4):424-37. PubMed ID: 20354164 [Abstract] [Full Text] [Related]
11. Nf1 loss promotes Kras-driven lung adenocarcinoma and results in Psat1-mediated glutamate dependence. Wang X, Min S, Liu H, Wu N, Liu X, Wang T, Li W, Shen Y, Wang H, Qian Z, Xu H, Zhao C, Chen Y. EMBO Mol Med; 2019 Jun 21; 11(6):. PubMed ID: 31036704 [Abstract] [Full Text] [Related]
12. Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes. Finnicum CT, Rahal Z, Hassane M, Treekitkarnmongkol W, Sinjab A, Morris R, Liu Y, Tang EL, Viet S, Petersen JL, Lorenzi PL, Tan L, Petrosino J, Hoffman KL, Fujimoto J, Moghaddam SJ, Kadara H. Int J Mol Sci; 2022 Sep 18; 23(18):. PubMed ID: 36142843 [Abstract] [Full Text] [Related]
14. Activation of MEK1/2-ERK1/2 signaling during NNK-induced lung carcinogenesis in female A/J mice. Yamakawa K, Yokohira M, Nakano Y, Kishi S, Kanie S, Imaida K. Cancer Med; 2016 May 18; 5(5):903-13. PubMed ID: 26864819 [Abstract] [Full Text] [Related]
17. G-protein coupled receptor family C, group 5, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients with chronic obstructive pulmonary disease and non-small-cell lung cancer. Fujimoto J, Kadara H, Garcia MM, Kabbout M, Behrens C, Liu DD, Lee JJ, Solis LM, Kim ES, Kalhor N, Moran C, Sharafkhaneh A, Lotan R, Wistuba II. J Thorac Oncol; 2012 Dec 18; 7(12):1747-1754. PubMed ID: 23154545 [Abstract] [Full Text] [Related]
18. Non-canonical genomic driver mutations of urethane carcinogenesis. Li S, Counter CM. PLoS One; 2022 Dec 18; 17(4):e0267147. PubMed ID: 35482806 [Abstract] [Full Text] [Related]
19. Definitive evidence for Club cells as progenitors for mutant Kras/Trp53-deficient lung cancer. Rosigkeit S, Kruchem M, Thies D, Kreft A, Eichler E, Boegel S, Jansky S, Siegl D, Kaps L, Pickert G, Haehnel P, Kindler T, Hartwig UF, Guerra C, Barbacid M, Schuppan D, Bockamp E. Int J Cancer; 2021 Nov 01; 149(9):1670-1682. PubMed ID: 34331774 [Abstract] [Full Text] [Related]
20. Genome-Wide Gene Expression Changes in the Normal-Appearing Airway during the Evolution of Smoking-Associated Lung Adenocarcinoma. Kantrowitz J, Sinjab A, Xu L, McDowell TL, Sivakumar S, Lang W, Nunomura-Nakamura S, Fukuoka J, Nemer G, Darwiche N, Chami H, Tfayli A, Wistuba II, Scheet P, Fujimoto J, Spira AE, Kadara H. Cancer Prev Res (Phila); 2018 Apr 01; 11(4):237-248. PubMed ID: 29382653 [Abstract] [Full Text] [Related] Page: [Next] [New Search]