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Journal Abstract Search

438 related items for PubMed ID: 28658992

  • 1. Biophysics: for HTS hit validation, chemical lead optimization, and beyond.
    Genick CC, Wright SK.
    Expert Opin Drug Discov; 2017 Sep; 12(9):897-907. PubMed ID: 28658992
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  • 3. Affinity-based screening techniques: their impact and benefit to increase the number of high quality leads.
    Bergsdorf C, Ottl J.
    Expert Opin Drug Discov; 2010 Nov; 5(11):1095-107. PubMed ID: 22827747
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  • 4. Non-stoichiometric inhibition in integrated lead finding - a literature review.
    Klumpp M.
    Expert Opin Drug Discov; 2016 Nov; 11(2):149-62. PubMed ID: 26653534
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  • 6. A Guide to Run Affinity Screens Using Differential Scanning Fluorimetry and Surface Plasmon Resonance Assays.
    Bergsdorf C, Wright SK.
    Methods Enzymol; 2018 Nov; 610():135-165. PubMed ID: 30390797
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  • 11. Early phase drug discovery: cheminformatics and computational techniques in identifying lead series.
    Duffy BC, Zhu L, Decornez H, Kitchen DB.
    Bioorg Med Chem; 2012 Sep 15; 20(18):5324-42. PubMed ID: 22938785
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  • 12. Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles.
    Sanders JM, Beshore DC, Culberson JC, Fells JI, Imbriglio JE, Gunaydin H, Haidle AM, Labroli M, Mattioni BE, Sciammetta N, Shipe WD, Sheridan RP, Suen LM, Verras A, Walji A, Joshi EM, Bueters T.
    J Med Chem; 2017 Aug 24; 60(16):6771-6780. PubMed ID: 28418656
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  • 13. Integration of virtual and high throughput screening in lead discovery settings.
    Polgár T, Keseru GM.
    Comb Chem High Throughput Screen; 2011 Dec 24; 14(10):889-97. PubMed ID: 21843143
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  • 14. Industrial medicinal chemistry insights: neuroscience hit generation at Janssen.
    Tresadern G, Rombouts FJR, Oehlrich D, Macdonald G, Trabanco AA.
    Drug Discov Today; 2017 Oct 24; 22(10):1478-1488. PubMed ID: 28669605
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  • 16. Modern drug discovery technologies: opportunities and challenges in lead discovery.
    Guido RV, Oliva G, Andricopulo AD.
    Comb Chem High Throughput Screen; 2011 Dec 24; 14(10):830-9. PubMed ID: 21843147
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  • 17. [Biophysical Analysis of the Protein-Small Molecule Interactions to Develop Small Molecule Drug Discovery].
    Nagatoishi S, Caaveiro JMM, Tsumoto K.
    Yakugaku Zasshi; 2018 Dec 24; 138(8):1033-1041. PubMed ID: 30068844
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  • 19. Hit Discovery for Public Target Programs in the European Lead Factory: Experiences and Output from Assay Development and Ultra-High-Throughput Screening.
    Honarnejad S, van Boeckel S, van den Hurk H, van Helden S.
    SLAS Discov; 2021 Feb 24; 26(2):192-204. PubMed ID: 32734803
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  • 20. Integrating biophysics with HTS-driven drug discovery projects.
    Folmer RH.
    Drug Discov Today; 2016 Mar 24; 21(3):491-8. PubMed ID: 26826422
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